| Literature DB >> 34281985 |
Jenny Lou Barican1, Donna Yung1, Christine Schwartz1, Yufei Zheng1, Katholiki Georgiades2, Charlotte Waddell3.
Abstract
QUESTION: Mental disorders typically start in childhood and persist, causing high individual and collective burdens. To inform policymaking to address children's mental health in high-income countries we aimed to identify updated data on disorder prevalence.Entities:
Keywords: child & adolescent psychiatry
Mesh:
Year: 2021 PMID: 34281985 PMCID: PMC8788041 DOI: 10.1136/ebmental-2021-300277
Source DB: PubMed Journal: Evid Based Ment Health ISSN: 1362-0347
Figure 1Search process. DSM, Diagnostic and Statistical Manual of Mental Disorders; ICD, International Classification of Diseases.
Childhood mental disorder prevalence study characteristics
| Study | Study location | Data collection year(s) | Sampling frame | Sample size* | Ages (years) | Diagnostic standard | Diagnostic measure† | Informant(s) | Timeframe‡ |
| Canino 2004s2 | Puerto Rico (USA) | 1999–2000 | Households | 1897 | 4–17 | DSM-IV | DISC-IV | Child or parent | 12 |
| Chen 2020s3 | Taiwan | 2015–2017 | Schools | 4816 | 7–14 | DSM-5 | K-SADS-E | Child | 6 |
| Costello 2003s4 | North Carolina (USA) | 1993–2000 | Schools | 1420 | 9–16 | DSM-IV | CAPA | Child or parent | 3 |
| Elberling 2015s5 | Copenhagen (Denmark) | 2000 | Population registry | 1585 | 5–7 | ICD-10 | DAWBA | Parent + teacher | 1–12 |
| Farbstein 2010s6 | Israel | 2004–2005 | Population registry | 957 | 14–17 | DSM-IV | DAWBA | Child + parent | 1–12 |
| Ford 2003s7 | England, Scotland, Wales (Great Britain) | 1999 | Households | 10 438 | 5–15 | DSM-IV | DAWBA | Child + parent + teacher | 1–12 |
| Georgiades 2019s8 | Ontario (Canada) | 2014–2015 | Households | 6537 | 4–17 | DSM-IV-TR | MINI-KID | Child/parent | 6 |
| Heiervang 2007s9 | Bergen (Norway) | 2002–2003 | Schools | 6297 | 8–10 | DSM-IV | DAWBA | Parent + teacher | 1–12 |
| Kessler 2012s1, s10 | USA | 2001–2004 | Households + schools | 6483 | 13–17 | DSM-IV | CIDI | Child or parent | 12 |
| Lawrence 2016s11 | Australia | 2013–2014 | Households | 6310 | 4–17 | DSM-IV | DISC-IV | Parent§ | 12 |
| Lesinkiene 2018s12 | Lithuania | 2004–2007 | Schools | 3309 | 7–16 | ICD-10 | DAWBA | Parent + child + teacher | 1–12 |
| Merikangas 2010s13 | USA | 2001–2004 | Population registry | 3042 | 8–15 | DSM-IV | DISC-IV | Child or parent | 12 |
| Park 2015s14 | Seoul (South Korea) | 2005–2006 | Schools | 1645 | 6–12 | DSM-IV | DISC-IV | Parent | 12 |
| Vicente 2012s15 | Cautin, Conception, Iquique, Santiago (Chile) | 2007–2009 | Households | 1558 | 4–18 | DSM-IV | DISC-IV | Child/parent | 12 |
+ Diagnoses determined using clinical judgement combining information from multiple informants. / Diagnoses determined relying on a single informant based either on disorders and/or age ranges; figure 2 gives details on data used in meta-analysis. (Online supplemental appendix D lists references s1 to s15). 'or' Diagnoses determined applying ‘OR’ rule whereby disorders were counted if diagnostic thresholds met by any informant (either child or parent).
*51.2% of participants were girls.
†Fully structured measures included CAPA, CIDI, DISC-IV and MINI-KID; semi-structured measures included DAWBA and K-SADS-E.
‡Duration over which symptoms/impairment were assessed; when a range of timeframes were provided, 12 month prevalence was chosen.
§While 11- to 17-year-olds were informants for one disorder, only parent reported estimates were used in meta-analyses due to insufficient data for calculating overall rate for 11- to 17-year-olds.
CAPA, Child and Adolescent Psychiatric Assessment; CIDI, Composite International Diagnostic Interview; DAWBA, Development and Well-Being Assessment; DISC-IV, Diagnostic Interview Schedule for Children; DSM, Diagnostic and Statistical Manual of Mental Disorders; ICD, International Statistical Classification of Diseases and Related Health Problems; K-SADS-E, Kiddie Schedule for Affective Disorders and Schizophrenia-Epidemiological; MINI-KID, Mini-International Neuropsychiatric Interview for Children and Adolescents.
Figure 2Forest plot for overall prevalence of any childhood mental disorder. Georgiades 2019s8 reported 18.2% of 4- to 11-year-olds (parent report) and 21.8% of 12- to 17-year-olds (child report) with any mental disorders. Vicente 2012s15 reported 27.8% of 4- to 11-year-olds (parent report) and 16.5% of 12- to 18-year-olds (child report) with any mental disorders. We report the weighted averages for these two studies in our meta-analysis.
Pooled prevalence of childhood mental disorders
| Disorder | Age* (years) | Number of studies | Sample size | Prevalence (%) (95% CI) |
| Any anxiety disorder† | 4–18 | 12 | 53 663 | 5.2 (3.2 to 8.2) |
| Specific phobia | 4–18 | 7 | 37 170 | 3.4 (1.9 to 5.9) |
| Separation anxiety disorder | 4–18 | 10 | 46 935 | 1.6 (1.0 to 2.6) |
| Social anxiety disorder | 4–18 | 10 | 46 935 | 1.2 (0.6 to 2.3) |
| Generalised anxiety disorder | 4–18 | 11 | 49 977 | 0.9 (0.4 to 1.7) |
| Panic disorder | 4–18 | 9 | 38 881 | 0.1 (0.1 to 0.3) |
| Agoraphobia | 4–18 | 5 | 26 691 | 0.1 (0.04 to 0.4) |
| Attention-deficit/hyperactivity disorder | 4–18 | 14 | 61 545 | 3.7 (2.3 to 5.7) |
| Oppositional defiant disorder | 4–18 | 10 | 47 299 | 3.3 (2.4 to 4.6) |
| Any substance use disorder‡ | 12–18 | 4 | 15 788 | 2.3 (2.1 to 2.6) |
| Alcohol use disorder | 12–18 | 3 | 9114 | 1.2 (1.0 to 1.4) |
| Cannabis use disorder | 12–18 | 2 | 2631 | 0.6 (0.4 to 1.0) |
| Any depressive disorder§ | 4–18 | 7 | 31 737 | 1.8 (0.8 to 3.8) |
| Major depressive disorder | 4–18 | 11 | 45 696 | 1.3 (0.6 to 2.9) |
| Dysthymia | 4–18 | 4 | 8142 | 0.2 (0.1 to 0.7) |
| Conduct disorder | 4–18 | 13 | 59 960 | 1.3 (0.8 to 2.3) |
| Autism spectrum disorder | 4–18 | 4 | 21 629 | 0.4 (0.2 to 0.8) |
| Obsessive-compulsive disorder | 4–18 | 7 | 33 769 | 0.3 (0.1 to 0.6) |
| Bipolar disorder | 12–18 | 2 | 8128 | 0.3 (0.1 to 1.1) |
| Eating disorders | 12–18 | 5 | 21 194 | 0.2 (0.1 to 0.5) |
| Post-traumatic stress disorder | 4–18 | 8 | 35 839 | 0.1 (0.04 to 0.4) |
| Schizophrenia | 12–18 | 2 | 5500 | 0.1 (0.1 to 0.3) |
| Any disorder¶ | 4–18 | 14 | 61 545 | 12.7 (10.1 to 15.9) |
*Earliest age in the ranges provided reflects when disorders typically emerge.2
†For any anxiety disorder, 6 studies included post-traumatic stress and/or obsessive-compulsive disorders.
‡For any substance use disorder, 2 studies included alcohol, cannabis, nicotine and other substances; 1 included alcohol and drugs; and one did not specify.
§For any depressive disorder, 4 studies included major depressive disorder (MDD) and dysthymia; 1 included MDD and depression not specifie; 1 included MDD, dysthymia and bipolar; and 1 did not specify.
¶Overall estimate for children with any disorder is less than the sum of estimates for the specific disorders because 26.5% of children had two or more disorders concurrently.
Figure 3Forest plot for prevalence of service use. Service use data for Costello 2003,s4 Farbstein 2010,s6 Kessler 2012s10 and Lawrence 2016s11 were obtained from the separate articles by Burns 1995, Mansbach-Kleinfeld 2010, Costello 2014 and Johnson 2016,39–42 respectively. Costello 2003s4 and Merikangas et al 2010s13 reported that 40.3% and 50.6%, respectively, of children with mental disorders received any services for their mental health problems; we report slight variations in our meta-analysis due to rounding. Georgiades 2019s8 reported that 61.5% of 4- to 11-year-olds (parent report) and 43.7% of 12- to 17-year-olds (child report) with mental disorders received any services for their mental health problems; we report the weighted average in our meta-analysis.