Literature DB >> 34264460

Evaluation of Staphylococcus aureus Antibiotic Tolerance Using Kill Curve Assays.

Jessica N Brandwein1, Kelly C Rice2.   

Abstract

This chapter describes the use of antibiotic kill curves to examine the tolerance of Staphylococcus aureus to any antibiotic of interest. This is done by treating cultures with a super-minimum inhibitory concentration (MIC) of antibiotic and measuring viability over time by colony-forming units (CFUs). Kill curves provide a unique insight into S. aureus antibiotic tolerance and death patterns that may not be clear from other experiments, such as traditional MIC or Kirby-Bauer assays.
© 2021. Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Antibiotic tolerance; CFU; Cell death; MIC; Persistence

Year:  2021        PMID： 34264460     DOI： 10.1007/978-1-0716-1550-8_7

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  24 in total

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Journal:  Essays Biochem       Date:  2017-03-03       Impact factor: 8.000

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Journal:  J Gen Microbiol       Date:  1986-05

Review 9.  Surviving as a Community: Antibiotic Tolerance and Persistence in Bacterial Biofilms.

Authors:  Jing Yan; Bonnie L Bassler
Journal:  Cell Host Microbe       Date:  2019-07-10       Impact factor: 21.023

Review 10.  Bacterial Metabolism and Antibiotic Efficacy.

Authors:  Jonathan M Stokes; Allison J Lopatkin; Michael A Lobritz; James J Collins
Journal:  Cell Metab       Date:  2019-07-03       Impact factor: 27.287
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