| Literature DB >> 34239998 |
José I de Granda-Orive1, José F Pascual-Lledó2, Santos Asensio-Sánchez2, Segismundo Solano-Reina3, Marcos García-Rueda4, Manuel Á Martínez-Muñiz5, Lourdes Lázaro-Asegurado6, Daniel Buljubasich7, Susana Luhning8, Roge-Lio Pendino7, Isabel Cienfuegos-Agustín1, Carlos A Jiménez-Ruiz9.
Abstract
INTRODUCTION: The aim of this study was to explore the utility of measuring motivation to quit smoking as a predictor of abstinence maintenance among smokers who wanted to quit and who were included in a multicenter study conducted in daily clinical practice.Entities:
Keywords: maintenance abstinence; motivation scales; regression analysis; smoking; smoking cessation; tobacco dependence
Year: 2021 PMID: 34239998 PMCID: PMC8240875 DOI: 10.18332/tpc/136506
Source DB: PubMed Journal: Tob Prev Cessat ISSN: 2459-3087
Figure 1Flowchart detailing subjects’ selection
Degree of significance of the different tests of motivation to quit smoking, controlling for the variables age, sex, and type of treatment, for the following variables[a]
| 0.786 | 0.661 | 0.197 | 0.112 | |
| 0.967 | 0.171 | 0.053 | 0.048 | |
| Health/prevention | 0.973 | 0.422 | 0.114 | 0.068 |
| Health/decrease in symptoms | 0.939 | 0.388 | 0.020 | 0.670 |
| Stop being dependent | 0.973 | 0.370 | 0.115 | 0.060 |
| Saving money | 0.973 | 0.398 | 0.136 | 0.079 |
| Quality of life | 0.973 | 0.419 | 0.182 | 0.063 |
| Do not harm my children/partner | 0.973 | 0.394 | 0.123 | 0.843 |
| Be a good example | 0.853 | 0.414 | 0.113 | 0.090 |
| Number of reasons for quit smoking | 0.820 | 0.431 | 0.123 | 0.096 |
| Father smokes/smoked | 0.951 | 0.476 | 0.340 | 0.035 |
| Mother smokes/smoked | 0.887 | 0.491 | 0.170 | 0.064 |
| Older brother smokes/smoked | 0.755 | 0.213 | 0.071 | 0.788 |
| Other brothers smoke | 0.894 | 0.360 | 0.062 | 0.020 |
| Friends smoke | 0.906 | 0.408 | 0.175 | 0.056 |
| Co-workers smoke | 0.976 | 0.640 | 0.243 | 0.193 |
| COPD | 0.986 | 0.362 | 0.040 | 0.401 |
| Asthma | 0.888 | 0.432 | 0.119 | 0.066 |
| Diabetes mellitus | 0.970 | 0.378 | 0.110 | 0.090 |
| Arterial hypertension | 0.888 | 0.568 | 0.127 | 0.080 |
| Ischemic heart disease | 0.888 | 0.745 | 0.116 | 0.129 |
| Lung cancer | 0.978 | 0.442 | 0.113 | 0.084 |
| Bladder cancer, cerebral stroke[ | - | - | - | - |
| Depression | 0.943 | 0.460 | 0.119 | 0.056 |
| Anxiety | 0.888 | 0.297 | 0.093 | 0.039 |
| Fagerström test | 0.730 | 0.484 | 0.136 | 0.071 |
| Heaviness of Smoking Index test | 0.730 | 0.471 | 0.117 | 0.064 |
| Pharmacological/psychological treatment type[ | 0.861 | 0.420 | 0.953 | 0.309 |
| Treatment alone vs combined[ | 0.917 | 0.270 | 0.191 | 0.358 |
| Varenicline alone or combined vs other treatments vs without treatment | 0.917 | 0.470 | 0.121 | 0.064 |
| Patches | 0.723 | 0.414 | 0.186 | 0.068 |
| Gums | 0.723 | 0.461 | 0.145 | 0.087 |
| Tablets | 0.723 | 0.473 | 0.169 | 0.790 |
| Oral spray | 0.723 | 0.581 | 0.075 | 0.098 |
| Patches + gums | 0.723 | 0.477 | 0.135 | 0.049 |
| Patches + tablets | 0.723 | 0.409 | 0.237 | 0.504 |
| Patches + oral spray | 0.723 | 0.456 | 0.110 | 0.526 |
| Other combinations[ | - | - | - | - |
| Number of NRT therapies | 0.723 | 0.533 | 0.196 | 0.076 |
| Varenicline alone | 0.723 | 0.554 | 0.206 | 0.077 |
| Bupropion alone | 0.693 | 0.498 | 0.250 | 0.072 |
| NRT alone | 0.805 | 0.623 | 0.194 | 0.396 |
| Age (years) | 0.730 | 0.531 | 0.150 | 0.581 |
| Sex | 0.730 | 0.534 | 0.187 | 0.610 |
| Age and sex | 0.730 | 0.506 | 0.147 | 0.127 |
| Age of initiation (years) | 0.956 | 0.019 | 0.129 | 0.053 |
| Cigarettes/day | 0.917 | 0.471 | 0.117 | 0.065 |
| Number of years smoking | 0.956 | 0.154 | 0.129 | 0.053 |
| Cumulative consumption (pack-years) | 0.956 | 0.451 | 0.125 | 0.056 |
| Number of previous quit attempts | 0.917 | 0.728 | 0.006 | 0.071 |
| Number of previous quit attempts (past/year) | 0.917 | 0.517 | 0.118 | 0.068 |
| Weight | 0.524 | 0.750 | 0.306 | 0.433 |
| Height | 0.709 | 0.721 | 0.220 | 0.010 |
| BMI | 0.709 | 0.760 | 0.275 | 0.073 |
| Carbon monoxide (ppm) | 0.598 | 0.061 | 0.012 | <0.001 |
| VAS | 0.917 | 0.470 | 0.119 | 0.066 |
| HMPMT | 0.917 | 0.721 | 0.155 | 0.585 |
| KWT | 0.917 | 0.875 | 0.192 | 0.093 |
RT: Richmond Test for quitting smoking. VAS: visual analogue scale. HMPMT: Henry Mondor Paris Motivation Test. KWT: Khimji-Watts Test. BMI: body mass index (kg/m2). NRT: nicotine replacement therapy. COPD: chronic obstructive pulmonary disease.
The models include the mentioned variables and all their possible interactions.
These variables were not analyzed as only one subject had this antecedent.
In the treatment models, the variable Type of treatment used so far, namely, Varenicline alone or Combined vs Other treatments vs No treatment that contains the categories No treatment, Other treatments, and Varenicline-containing treatments, is replaced by the specific treatment variable mentioned.
Categorized as: No treatment (Reference category), Only pharmacological treatment, Only psychological treatment, and Pharmacological and psychological treatment.
Categorized as: No treatment (Reference category), Varenicline, Bupropion or NRT alone, and Combined treatment (Varenicline + NRT, Varenicline + Bupropion, or Bupropion + NRT).
Nicotine replacement therapy.
Other combinations of nicotine replacement therapy were not studied due to the small number of effective treatments.
The models with the variables: Age only, Sex only, and Age and Sex, do not include the variable Treatment. Starting with the variable Age of initiation, the models include the variables mentioned in the title of the table.
Logistic regression models for the VAS motivational test, the HMPMT and KWT
| HMPMT | 1.52 | <0.001 | 1.21 | 1.91 |
| Health/decrease in symptom motivation [yes vs no (Ref.)] | 60.07 | 0.009 | 2.75 | 1311.35 |
| Number of previous quit attempts | 3.54 | 0.004 | 1.48 | 8.46 |
| Level of studies [secondary vs basic/university (Ref.)] | 7.40 | 0.000 | 2.77 | 19.80 |
| HMPMT × Health/decrease in symptom motivation | 0.78 | 0.026 | 0.62 | 0.97 |
| HMPMT × Number of previous quit attempts | 0.91 | 0.005 | 0.85 | 0.97 |
| Health/decrease in symptom motivation × Level of studies | 0.16 | 0.002 | 0.05 | 0.51 |
| Visual analogue scale | 2.33 | 0.019 | 1.15 | 4.73 |
| Age of initiation | 1.49 | 0.030 | 1.04 | 2.15 |
| Visual analogue scale × Age of initiation | 0.95 | 0.024 | 0.91 | 0.99 |
| KWT | 0.07 | 0.018 | 0.01 | 0.64 |
| Sex [male vs female (Ref.)] | 142.04 | 0.006 | 4.03 | 5008.56 |
| Father smokes/smoked [yes vs no (Ref.)] | 3.09 | 0.002 | 1.53 | 6.22 |
| Height (cm) | 0.81 | 0.010 | 0.68 | 0.95 |
| Number of NRT therapies (Ref.) | 0.68 | 0.035 | 0.47 | 0.97 |
| KWT × Sex | 0.65 | 0.005 | 0.48 | 0.88 |
| KWT × Height | 1.02 | 0.012 | 1.00 | 1.03 |
| KWT | 1.13 | 0.081 | 0.98 | 1.30 |
| Sex [male vs female (Ref.)] | 7.54 | 0.097 | 0.69 | 82.18 |
| Sex [male vs female (Ref.)] | 1.98 | 0.027 | 1.08 | 3.62 |
| Number of NRT therapies (Ref.) | 0.78 | 0.113 | 0.57 | 1.06 |
| KWT × Sex | 0.83 | 0.075 | 0.68 | 1.02 |
OR: odds ratio.
Figure 2Graphic representation of the distribution of predicted probabilities according to the model in Table 2 for the different combinations of values of dummy subjects of the variables Henri Mondor Paris Motivation Test, Number of previous quit attempts, Level of studies, and Reason to quit smoking (Health/decrease in symptoms)
Figure 3ROC curves corresponding to the logistic regression models of the Visual Analogue Scale and the Henri Mondor Paris Motivation Test