Literature DB >> 34237180

Co-ingestion of prescription drugs and alcohol in US adults aged 50 years or older.

Ty S Schepis1,2, Jason A Ford2,3, Sean Esteban McCabe2,4,5,6,7.   

Abstract

OBJECTIVE: To examine prevalence of past-month prescription drug misuse (PDM) and alcohol co-ingestion and its correlates in adults age 50 or older.
METHODS: Data were from the 2015-2018 US National Survey on Drug Use and Health (n = 35,190). PDM-alcohol co-ingestion was defined as prescription opioid, tranquilizer/sedative, or stimulant misuse while "drinking alcohol or within a couple of hours of drinking." Co-ingestion prevalence was estimated, and logistic and negative binomial regressions examined the sociodemographic, physical health, mental health, substance use, and substance use disorder (SUD) correlates of co-ingestion.
RESULTS: Over 344,000 adults aged 50 years or older (0.3%) engaged in past-month PDM-alcohol co-ingestion, or 27.4% of those with past-month PDM. Past-month co-ingestion was linked to greater past-month alcohol use frequency and elevated adjusted odds ratios (aORs) for all examined substance use outcomes (e.g., non-PDM SUD aOR = 21.8; 49.7% prevalence rate). The aOR for suicidal ideation was 506% higher in those with co-ingestion than those without past-year PDM.
CONCLUSIONS: US adults aged 50 years or older with past-month PDM-alcohol co-ingestion are at high risk for SUD and concerning mental health symptoms. Screening for mental health and substance use treatment is warranted among aging adults with signs of PDM, especially involving co-ingestion.
© 2021 John Wiley & Sons Ltd.

Entities:  

Keywords:  alcohol; older adults; prescription opioid; stimulant; tranquilizer

Mesh:

Substances:

Year:  2021        PMID: 34237180      PMCID: PMC9254454          DOI: 10.1002/hup.2803

Source DB:  PubMed          Journal:  Hum Psychopharmacol        ISSN: 0885-6222            Impact factor:   2.130


  45 in total

1.  Prescription opioid misuse and comorbid substance use: Past 30-day prevalence, correlates and co-occurring behavioral indicators in the 2016 National Survey on Drug Use and Health.

Authors:  Timothy J Grigsby; Jeffrey T Howard
Journal:  Am J Addict       Date:  2019-01-31

2.  Shifting characteristics of nonmedical prescription tranquilizer users in the United States, 2005-2014.

Authors:  Joseph J Palamar; Benjamin H Han; Silvia S Martins
Journal:  Drug Alcohol Depend       Date:  2018-12-08       Impact factor: 4.492

Review 3.  Prescription Opioid Misuse Among Adolescents.

Authors:  Jason A Ford
Journal:  Pediatr Clin North Am       Date:  2019-12       Impact factor: 3.278

4.  Reliability and consistency in self-reports of drug use.

Authors:  P M O'Malley; J G Bachman; L D Johnston
Journal:  Int J Addict       Date:  1983-08

5.  Concurrent versus simultaneous use of alcohol and non-medical use of prescription drugs: is simultaneous use worse for mental, social, and health issues?

Authors:  Stéphanie Baggio; Stéphane Deline; Joseph Studer; Alexandra N'Goran; Meichun Mohler-Kuo; Jean-Bernard Daeppen; Gerhard Gmel
Journal:  J Psychoactive Drugs       Date:  2014 Oct-Dec

6.  The relationship between past 12-month suicidality and reasons for prescription opioid misuse.

Authors:  Lisham Ashrafioun; Sarah Heavey; Taraneh Canarapen; Todd M Bishop; Wilfred R Pigeon
Journal:  J Affect Disord       Date:  2019-02-06       Impact factor: 4.839

Review 7.  The Alcohol Use Disorders Identification Test (AUDIT): a review of recent research.

Authors:  Duane F Reinert; John P Allen
Journal:  Alcohol Clin Exp Res       Date:  2002-02       Impact factor: 3.455

8.  Risk factors for severe respiratory depression from prescription opioid overdose.

Authors:  Lindsay M Fox; Robert S Hoffman; David Vlahov; Alex F Manini
Journal:  Addiction       Date:  2017-09-06       Impact factor: 6.526

9.  Changes in mental health, pain, and drug misuse since the mid-1990s: Is there a link?

Authors:  Dana A Glei; Andrew Stokes; Maxine Weinstein
Journal:  Soc Sci Med       Date:  2020-01-07       Impact factor: 4.634

10.  Prescription Opioid Use, Misuse, and Use Disorders in U.S. Adults: 2015 National Survey on Drug Use and Health.

Authors:  Beth Han; Wilson M Compton; Carlos Blanco; Elizabeth Crane; Jinhee Lee; Christopher M Jones
Journal:  Ann Intern Med       Date:  2017-08-01       Impact factor: 25.391

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