Literature DB >> 30753953

The relationship between past 12-month suicidality and reasons for prescription opioid misuse.

Lisham Ashrafioun1, Sarah Heavey2, Taraneh Canarapen3, Todd M Bishop4, Wilfred R Pigeon4.   

Abstract

BACKGROUND: Understanding reasons for prescription opioid misuse can help elucidate suicide prevention efforts. The goal of the current study is to assess associations of reasons for prescription opioid misuse subtypes and suicide-related variables. We also assessed whether prescription opioid misuse differentiates ideators from those who attempt suicide.
METHODS: Using data from the 2015-2017 National Survey of Drug Use and Health (N = 45,074), prescription opioid misuse subtypes were grouped as follows: (a) Pain only, (b) Other reasons, and (c) Mixed reasons (i.e., pain and at least one other reason). Logistic regressions examined associations of misuse subtypes and past 12-month suicide-related variables (ideation, planning, attempts) relative to non-misusers. Logistic regression analyses were also conducted among the subset reporting ideation to assess whether prescription opioid misuse differentiated ideators with no attempt from ideators with an attempt.
RESULTS: In adjusted models, the Pain only and the Other reasons subtypes were associated with ideation and planning, but not attempts. The Mixed reasons subtype had higher odds of suicide ideation and planning compared to those not misusing prescription opioids and the Pain only misuse subtype. The Mixed reasons subtype had higher odds of a suicide attempt only when compared to those not misusing prescription opioids. Prescription opioid misuse was also associated with suicide attempts among the subset of ideators.
CONCLUSIONS: Findings indicate that people misuse prescription opioids for various reasons, and misuse subtypes are associated with past 12-month suicidality. Addressing pain and other reasons for misuse together through use of evidence-based treatments may help mitigate suicide risk. Published by Elsevier B.V.

Entities:  

Keywords:  Motives; Prescription opioid misuse; Subtypes; Suicide attempts; Suicide ideation

Mesh:

Year:  2019        PMID: 30753953      PMCID: PMC7870327          DOI: 10.1016/j.jad.2019.02.008

Source DB:  PubMed          Journal:  J Affect Disord        ISSN: 0165-0327            Impact factor:   4.839


  31 in total

1.  Severe pain predicts greater likelihood of subsequent suicide.

Authors:  Mark A Ilgen; Kara Zivin; Karen L Austin; Amy S B Bohnert; Ewa K Czyz; Marcia Valenstein; Amy M Kilbourne
Journal:  Suicide Life Threat Behav       Date:  2010-12

2.  Trends in prescription drug abuse and dependence, co-occurrence with other substance use disorders, and treatment utilization: results from two national surveys.

Authors:  Sean Esteban McCabe; James A Cranford; Brady T West
Journal:  Addict Behav       Date:  2008-06-12       Impact factor: 3.913

3.  Medical use, medical misuse, and nonmedical use of prescription opioids: results from a longitudinal study.

Authors:  Sean Esteban McCabe; Brady T West; Carol J Boyd
Journal:  Pain       Date:  2013-01-26       Impact factor: 6.961

4.  Frequency of prescription opioid misuse and suicidal ideation, planning, and attempts.

Authors:  Lisham Ashrafioun; Todd M Bishop; Kenneth R Conner; Wilfred R Pigeon
Journal:  J Psychiatr Res       Date:  2017-03-19       Impact factor: 4.791

Review 5.  Understanding Links among Opioid Use, Overdose, and Suicide.

Authors:  Amy S B Bohnert; Mark A Ilgen
Journal:  N Engl J Med       Date:  2019-01-03       Impact factor: 91.245

Review 6.  The prevalence of mental health and pain symptoms in general population samples reporting nonmedical use of prescription opioids: a systematic review and meta-analysis.

Authors:  Benedikt Fischer; Anna Lusted; Michael Roerecke; Benjamin Taylor; Jürgen Rehm
Journal:  J Pain       Date:  2012-10-03       Impact factor: 5.820

7.  ED visits for drug-related poisoning in the United States, 2007.

Authors:  Yuxi Xiang; Weiyan Zhao; Huiyun Xiang; Gary A Smith
Journal:  Am J Emerg Med       Date:  2011-03-02       Impact factor: 2.469

Review 8.  Suicide and suicidal behaviour.

Authors:  Gustavo Turecki; David A Brent
Journal:  Lancet       Date:  2015-09-15       Impact factor: 79.321

9.  Noncancer pain conditions and risk of suicide.

Authors:  Mark A Ilgen; Felicia Kleinberg; Rosalinda V Ignacio; Amy S B Bohnert; Marcia Valenstein; John F McCarthy; Frederic C Blow; Ira R Katz
Journal:  JAMA Psychiatry       Date:  2013-07       Impact factor: 21.596

10.  Opioid dose and risk of suicide.

Authors:  Mark A Ilgen; Amy S B Bohnert; Dara Ganoczy; Matthew J Bair; John F McCarthy; Frederic C Blow
Journal:  Pain       Date:  2016-05       Impact factor: 7.926

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  6 in total

1.  The association of prescription opioid use with suicide attempts: An analysis of statewide medical claims data.

Authors:  Chongliang Luo; Kun Chen; Riddhi Doshi; Nathaniel Rickles; Yong Chen; Harold Schwartz; Robert H Aseltine
Journal:  PLoS One       Date:  2022-06-30       Impact factor: 3.752

2.  National Trends in Suicide Thoughts and Behavior among US Adults with Opioid Use Disorder from 2015 to 2020.

Authors:  Joanna M Streck; Maria A Parker; Benjamin Bearnot; Kelly Kalagher; Stacey C Sigmon; Renee D Goodwin; Andrea H Weinberger
Journal:  Subst Use Misuse       Date:  2022-03-02       Impact factor: 2.362

Review 3.  Health harms of non-medical prescription opioid use: A systematic review.

Authors:  Dan Werb; Ayden I Scheim; Ayorinde Soipe; Samantha Aeby; Indhu Rammohan; Benedikt Fischer; Scott E Hadland; Brandon D L Marshall
Journal:  Drug Alcohol Rev       Date:  2022-04-18

4.  Co-ingestion of prescription drugs and alcohol in US adults aged 50 years or older.

Authors:  Ty S Schepis; Jason A Ford; Sean Esteban McCabe
Journal:  Hum Psychopharmacol       Date:  2021-07-08       Impact factor: 2.130

Review 5.  Prescription Drug Misuse: Taking a Lifespan Perspective.

Authors:  Ty S Schepis; Dalton L Klare; Jason A Ford; Sean Esteban McCabe
Journal:  Subst Abuse       Date:  2020-03-05

6.  A comprehensive multivariate model of biopsychosocial factors associated with opioid misuse and use disorder in a 2017-2018 United States national survey.

Authors:  Francisco A Montiel Ishino; Philip R McNab; Tamika Gilreath; Bonita Salmeron; Faustine Williams
Journal:  BMC Public Health       Date:  2020-11-18       Impact factor: 3.295

  6 in total

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