Literature DB >> 34232682

The Gut-Arterial Stiffness Axis: Is TMAO a Novel Target to Prevent Age-Related Aortic Stiffening?

Gary L Pierce1,2,3,4, Stephen J Roy1,3, Colin J Gimblet1.   

Abstract

Entities:  

Keywords:  blood pressure; cardiovascular disease; carotid femoral pulse wave velocity; editorials; microbiota; trimethylamine

Mesh：

Substances：

Year:  2021        PMID： 34232682      PMCID： PMC8274311          DOI： 10.1161/HYPERTENSIONAHA.121.17487

Source DB:  PubMed          Journal:  Hypertension        ISSN： 0194-911X            Impact factor:   9.897


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  11 in total

1.  Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.

Authors:  Zeneng Wang; Adam B Roberts; Jennifer A Buffa; Bruce S Levison; Weifei Zhu; Elin Org; Xiaodong Gu; Ying Huang; Maryam Zamanian-Daryoush; Miranda K Culley; Anthony J DiDonato; Xiaoming Fu; Jennie E Hazen; Daniel Krajcik; Joseph A DiDonato; Aldons J Lusis; Stanley L Hazen
Journal:  Cell       Date:  2015-12-17       Impact factor: 41.582

Review 2.  Targeting of microbe-derived metabolites to improve human health: The next frontier for drug discovery.

Authors:  J Mark Brown; Stanley L Hazen
Journal:  J Biol Chem       Date:  2017-04-07       Impact factor: 5.157

3.  Suppression of the gut microbiome ameliorates age-related arterial dysfunction and oxidative stress in mice.

Authors:  Vienna E Brunt; Rachel A Gioscia-Ryan; James J Richey; Melanie C Zigler; Lauren M Cuevas; Antonio Gonzalez; Yoshiki Vázquez-Baeza; Micah L Battson; Andrew T Smithson; Andrew D Gilley; Gail Ackermann; Andrew P Neilson; Tiffany Weir; Kevin P Davy; Rob Knight; Douglas R Seals
Journal:  J Physiol       Date:  2019-02-27       Impact factor: 5.182

4.  Renoprotective antioxidant effect of alagebrium in experimental diabetes.

Authors:  Jehyun Park; Min Kyung Kwon; Joo Young Huh; Won Jun Choi; Lak Shin Jeong; Ryoji Nagai; Wan Young Kim; Jin Kim; Geun Taek Lee; Hi Bahl Lee; Hunjoo Ha
Journal:  Nephrol Dial Transplant       Date:  2011-04-08       Impact factor: 5.992

5.  Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE.

Authors:  M P Wautier; O Chappey; S Corda; D M Stern; A M Schmidt; J L Wautier
Journal:  Am J Physiol Endocrinol Metab       Date:  2001-05       Impact factor: 4.310

Review 6.  Gut Microbiota and Cardiovascular Disease.

Authors:  Marco Witkowski; Taylor L Weeks; Stanley L Hazen
Journal:  Circ Res       Date:  2020-07-30       Impact factor: 17.367

7.  Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry.

Authors:  Zeneng Wang; Bruce S Levison; Jennie E Hazen; Lillian Donahue; Xin-Min Li; Stanley L Hazen
Journal:  Anal Biochem       Date:  2014-04-01       Impact factor: 3.365

8.  Gut Microbiome-Derived Metabolite Trimethylamine N-Oxide Induces Aortic Stiffening and Increases Systolic Blood Pressure With Aging in Mice and Humans.

Authors:  Vienna E Brunt; Abigail G Casso; Rachel A Gioscia-Ryan; Zachary J Sapinsley; Brian P Ziemba; Zachary S Clayton; Amy E Bazzoni; Nicholas S VanDongen; James J Richey; David A Hutton; Melanie C Zigler; Andrew P Neilson; Kevin P Davy; Douglas R Seals
Journal:  Hypertension       Date:  2021-05-10       Impact factor: 9.897

9.  Effects of Lifestyle Intervention on Plasma Trimethylamine N-Oxide in Obese Adults.

Authors:  Melissa L Erickson; Steven K Malin; Zeneng Wang; J Mark Brown; Stanley L Hazen; John P Kirwan
Journal:  Nutrients       Date:  2019-01-16       Impact factor: 5.717

10.  The gut microbiome-derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging.

Authors:  Vienna E Brunt; Thomas J LaRocca; Amy E Bazzoni; Zachary J Sapinsley; Jill Miyamoto-Ditmon; Rachel A Gioscia-Ryan; Andrew P Neilson; Christopher D Link; Douglas R Seals
Journal:  Geroscience       Date:  2020-08-29       Impact factor: 7.581
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  1 in total

Review 1.  Metabolomics of Arterial Stiffness.

Authors:  Kaido Paapstel; Jaak Kals
Journal:  Metabolites       Date:  2022-04-20
  1 in total

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