Literature DB >> 34232361

Single stage reconstruction of segmental skeletal defects by bone graft in a synthetic membrane.

Mostafa Abdelkhalek1, Barakat S El-Alfy2, Ayman M Ali1.   

Abstract

INTRODUCTION: Segmental skeletal defects are very difficult to treat. The current options are lengthy procedures, require more than one surgery and plagued with many complications. The aim of this study is to assess the results of bone graft in surgicel as a synthetic membrane for reconstruction of segmental skeletal defects in one stage surgery.
METHODS: Fourteen patients with segmental skeletal defects were included in the study. The ages ranged from 20 to 54 years with an average of 32 years. The defects were due to high energy trauma in all cases. The size of the defects ranged from 5 to 12 cm with an average of 7 cm. They were located in the distal femur in 11 cases and middle third of the femur in three cases. All cases were treated by the synthetic membrane technique in one stage surgery. Surgicel was used as a synthetic membrane and both the fibular strut autograft and morselized allograft were used to fill the defects in all patients.
RESULTS: All cases healed without additional procedures after the index surgery except in three cases. The time-to-bone union ranged from six to 13 months with an average of eight months. After physiotherapy all patients regained good range of knee movements except two cases. The complications included deep wound infection in two cases, nonunion of the graft in one case and joint stiffness in two cases.
CONCLUSION: Primary bone graft in surgicel as a synthetic membrane is a good technique for management of post-traumatic bone defects. It reduces the time and number of surgeries required for reconstruction of this difficult problem.

Entities:  

Keywords:  Bone defects; Induced membrane technique; Membrane guided growth; Oxidized cellulose; Synthetic membrane technique

Year:  2021        PMID: 34232361     DOI: 10.1007/s00264-021-05078-2

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  27 in total

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Authors:  A C Masquelet; F Fitoussi; T Begue; G P Muller
Journal:  Ann Chir Plast Esthet       Date:  2000-06       Impact factor: 0.660

Review 2.  Management of posttraumatic segmental bone defects.

Authors:  Thomas A DeCoster; Rick J Gehlert; Elizabeth A Mikola; Miguel A Pirela-Cruz
Journal:  J Am Acad Orthop Surg       Date:  2004 Jan-Feb       Impact factor: 3.020

Review 3.  The concept of induced membrane for reconstruction of long bone defects.

Authors:  Alain C Masquelet; Thierry Begue
Journal:  Orthop Clin North Am       Date:  2010-01       Impact factor: 2.472

4.  Treatment of posttraumatic bone defects by the induced membrane technique.

Authors:  C Karger; T Kishi; L Schneider; F Fitoussi; A-C Masquelet
Journal:  Orthop Traumatol Surg Res       Date:  2012-01-12       Impact factor: 2.256

5.  The use of free nonvascularized fibular graft in the induced membrane technique to manage post-traumatic bone defects.

Authors:  Barakat El-Alfy; Mazen Abulsaad; Wail Lotfy Abdelnaby
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-02-14

6.  Masquelet technique for the treatment of bone defects: tips-tricks and future directions.

Authors:  Peter V Giannoudis; Omar Faour; Thomas Goff; Nikolaos Kanakaris; Rozalia Dimitriou
Journal:  Injury       Date:  2011-05-04       Impact factor: 2.586

7.  Induction of a barrier membrane to facilitate reconstruction of massive segmental diaphyseal bone defects: an ovine model.

Authors:  Véronique Viateau; Geneviève Guillemin; Yolande Calando; Delphine Logeart; Karim Oudina; Laurent Sedel; Didier Hannouche; Valérie Bousson; Hervé Petite
Journal:  Vet Surg       Date:  2006-07       Impact factor: 1.495

8.  Induced membranes secrete growth factors including vascular and osteoinductive factors and could stimulate bone regeneration.

Authors:  Ph Pelissier; A C Masquelet; R Bareille; S Mathoulin Pelissier; J Amedee
Journal:  J Orthop Res       Date:  2004-01       Impact factor: 3.494

9.  Surgical membranes as directional delivery devices to generate tissue: testing in an ovine critical sized defect model.

Authors:  Melissa L Knothe Tate; Hana Chang; Shannon R Moore; Ulf R Knothe
Journal:  PLoS One       Date:  2011-12-12       Impact factor: 3.240

10.  The study of the feasibility of segmental bone defect repair with tissue- engineered bone membrane: a qualitative observation.

Authors:  Lin Zhao; Jun-Li Zhao; Lin Wan; Shuan-Ke Wang
Journal:  Strategies Trauma Limb Reconstr       Date:  2008-04-12
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