Literature DB >> 34223935

Factors associated with late-life psychosis in primary care older adults without a diagnosis of dementia.

Helen-Maria Vasiliadis1, Isabelle Pitrou2, Catherine Lamoureux-Lamarche2, Sébastien Grenier3, Patrick Viet-Quoc Nguyen4, Carol Hudon5.   

Abstract

PURPOSE: The epidemiology of late-life psychosis (LLP) remains unclear comparatively to early-onset psychosis. The study aims to estimate the prevalence and incidence of LLP over a 3-year period and examine the correlates of LLP in community-living older adults aged ≥ 65 years recruited in primary care.
METHODS: Study sample included N = 1481 primary care older adults participating in the Étude sur la Santé des Aînés (ESA)-Services study. Diagnoses were obtained from health administrative and self-reported data in the 3 years prior and following baseline interview. The prevalence and incidence of LLP (number of cases) were identified in the 3-year period following interview. Participants with dementia or psychosis related to dementia were excluded. Logistic regressions were used to ascertain the correlates of LLP as function of various individual and health system factors.
RESULTS: The 3-year prevalence and incidence of LLP was 4.7% (95% CI = 3.64-5.81) and 2.8% (95% CI = 1.99-3.68), respectively. Factors associated with both prevalent and incident LLP included functional status, number of physical diseases, hospitalizations, continuity of care and physical activity. Older age and the presence of suicidal ideation were associated with incident LLP, while higher education, a depressive disorder and a history of sexual assault were associated with persistent cases.
CONCLUSIONS: Results highlight the importance of LLP in primary care older adult patients without dementia. Health system factors were consistent determinants of prevalent and incident LLP, suggesting the need for better continuity of care in at-risk primary care older adults.
© 2021. Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Ageing; Chronic diseases; Disability; Late-life psychosis; Mental health

Mesh:

Year:  2021        PMID: 34223935     DOI: 10.1007/s00127-021-02132-7

Source DB:  PubMed          Journal:  Soc Psychiatry Psychiatr Epidemiol        ISSN: 0933-7954            Impact factor:   4.328


  60 in total

1.  An initial study of modifiable and non-modifiable factors for late-life psychosis.

Authors:  Obiora E Onwuameze; Susan K Schultz; Sergio Paradiso
Journal:  Int J Psychiatry Med       Date:  2011       Impact factor: 1.210

2.  Risk factors in early and late onset schizophrenia.

Authors:  Laura Chen; Ajit Selvendra; Anne Stewart; David Castle
Journal:  Compr Psychiatry       Date:  2017-09-20       Impact factor: 3.735

Review 3.  Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis: an international consensus. The International Late-Onset Schizophrenia Group.

Authors:  R Howard; P V Rabins; M V Seeman; D V Jeste
Journal:  Am J Psychiatry       Date:  2000-02       Impact factor: 18.112

4.  Late-onset psychosis and very-late-onset-schizophrenia-like-psychosis: an updated systematic review.

Authors:  Y N Suen; Stephanie M Y Wong; Christy L M Hui; Sherry K W Chan; Edwin H M Lee; Wing C Chang; Eric Y H Chen
Journal:  Int Rev Psychiatry       Date:  2019-10-10

5.  The Economic Burden of Chronic Psychotic Disorders in Ontario.

Authors:  Claire de Oliveira; Joyce Cheng; Juergen Rehm; Paul Kurdyak
Journal:  J Ment Health Policy Econ       Date:  2016-12-01

Review 6.  Late-life psychosis: diagnosis and treatment.

Authors:  Michael M Reinhardt; Carl I Cohen
Journal:  Curr Psychiatry Rep       Date:  2015-02       Impact factor: 5.285

7.  Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study.

Authors:  Yonas E Geda; Rosebud O Roberts; David S Knopman; Ronald C Petersen; Teresa J H Christianson; Vernon S Pankratz; Glenn E Smith; Bradley F Boeve; Robert J Ivnik; Eric G Tangalos; Walter A Rocca
Journal:  Arch Gen Psychiatry       Date:  2008-10

8.  The incidence of very late-onset psychotic disorders: a systematic review and meta-analysis, 1960-2016.

Authors:  Jean Stafford; Robert Howard; James B Kirkbride
Journal:  Psychol Med       Date:  2017-12-04       Impact factor: 7.723

9.  Behavioural and psychological symptoms in the older population without dementia--relationship with socio-demographics, health and cognition.

Authors:  Rianne van der Linde; Blossom C M Stephan; Fiona E Matthews; Carol Brayne; George M Savva
Journal:  BMC Geriatr       Date:  2010-11-30       Impact factor: 3.921

Review 10.  Psychotic disorders in late life: a narrative review.

Authors:  Rajesh R Tampi; Juan Young; Rakin Hoq; Kyle Resnick; Deena J Tampi
Journal:  Ther Adv Psychopharmacol       Date:  2019-10-16
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