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Literature DB >> 34217916

Mining for novel antibiotics.

Justin R Randall¹, Bryan W Davies².

Abstract

Entities: Chemical

Mesh：

Substances：
Anti-Bacterial Agents

Year: 2021 PMID： 34217916 PMCID： PMC8463434 DOI： 10.1016/j.mib.2021.06.001

Source DB: PubMed Journal: Curr Opin Microbiol ISSN： 1369-5274 Impact factor: 7.584

× No keyword cloud information.

41 in total

1. A multifunctional bispecific antibody protects against Pseudomonas aeruginosa.

Authors: Antonio DiGiandomenico; Ashley E Keller; Cuihua Gao; Godfrey J Rainey; Paul Warrener; Mareia M Camara; Jessica Bonnell; Ryan Fleming; Binyam Bezabeh; Nazzareno Dimasi; Bret R Sellman; Jamese Hilliard; Caitlin M Guenther; Vivekananda Datta; Wei Zhao; Changshou Gao; Xiang-Qing Yu; JoAnn A Suzich; C Kendall Stover
Journal: Sci Transl Med Date: 2014-11-12 Impact factor: 17.956

Review 2. Why is big Pharma getting out of antibacterial drug discovery?

Authors: Steven J Projan
Journal: Curr Opin Microbiol Date: 2003-10 Impact factor: 7.934

Review 3. Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?

Authors: Richard H Baltz
Journal: J Ind Microbiol Biotechnol Date: 2006-01-18 Impact factor: 3.346

4. Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial species.

Authors: D Nichols; N Cahoon; E M Trakhtenberg; L Pham; A Mehta; A Belanger; T Kanigan; K Lewis; S S Epstein
Journal: Appl Environ Microbiol Date: 2010-02-19 Impact factor: 4.792

5. A new antibiotic kills pathogens without detectable resistance.

Authors: Losee L Ling; Tanja Schneider; Aaron J Peoples; Amy L Spoering; Ina Engels; Brian P Conlon; Anna Mueller; Till F Schäberle; Dallas E Hughes; Slava Epstein; Michael Jones; Linos Lazarides; Victoria A Steadman; Douglas R Cohen; Cintia R Felix; K Ashley Fetterman; William P Millett; Anthony G Nitti; Ashley M Zullo; Chao Chen; Kim Lewis
Journal: Nature Date: 2015-01-07 Impact factor: 49.962

6. Predictive compound accumulation rules yield a broad-spectrum antibiotic.

Authors: Michelle F Richter; Bryon S Drown; Andrew P Riley; Alfredo Garcia; Tomohiro Shirai; Riley L Svec; Paul J Hergenrother
Journal: Nature Date: 2017-05-10 Impact factor: 49.962

7. A Deep Learning Approach to Antibiotic Discovery.

Authors: Jonathan M Stokes; Kevin Yang; Kyle Swanson; Wengong Jin; Andres Cubillos-Ruiz; Nina M Donghia; Craig R MacNair; Shawn French; Lindsey A Carfrae; Zohar Bloom-Ackermann; Victoria M Tran; Anush Chiappino-Pepe; Ahmed H Badran; Ian W Andrews; Emma J Chory; George M Church; Eric D Brown; Tommi S Jaakkola; Regina Barzilay; James J Collins
Journal: Cell Date: 2020-04-16 Impact factor: 41.582

Mining for novel antibiotics.

1. A multifunctional bispecific antibody protects against Pseudomonas aeruginosa.

Review 2. Why is big Pharma getting out of antibacterial drug discovery?

Review 3. Marcel Faber Roundtable: is our antibiotic pipeline unproductive because of starvation, constipation or lack of inspiration?

4. Use of ichip for high-throughput in situ cultivation of "uncultivable" microbial species.

5. A new antibiotic kills pathogens without detectable resistance.

6. Predictive compound accumulation rules yield a broad-spectrum antibiotic.

7. A Deep Learning Approach to Antibiotic Discovery.

8. Machine-learning techniques applied to antibacterial drug discovery.

9. Design of stapled antimicrobial peptides that are stable, nontoxic and kill antibiotic-resistant bacteria in mice.

10. Toward Autonomous Antibiotic Discovery.

Review 1. MDR Pumps as Crossroads of Resistance: Antibiotics and Bacteriophages.

2. Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic.