Literature DB >> 32302574

A Deep Learning Approach to Antibiotic Discovery.

Jonathan M Stokes, Kevin Yang, Kyle Swanson, Wengong Jin, Andres Cubillos-Ruiz, Nina M Donghia, Craig R MacNair, Shawn French, Lindsey A Carfrae, Zohar Bloom-Ackermann, Victoria M Tran, Anush Chiappino-Pepe, Ahmed H Badran, Ian W Andrews, Emma J Chory, George M Church, Eric D Brown, Tommi S Jaakkola, Regina Barzilay, James J Collins.   

Abstract

Year:  2020        PMID： 32302574     DOI： 10.1016/j.cell.2020.04.001

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


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  21 in total

1.  Unconventional Antibacterials and Adjuvants.

Authors:  Mayland Chang; Kiran V Mahasenan; Juan A Hermoso; Shahriar Mobashery
Journal:  Acc Chem Res       Date:  2021-01-29       Impact factor: 22.384

Review 2.  A guide to machine learning for biologists.

Authors:  Joe G Greener; Shaun M Kandathil; Lewis Moffat; David T Jones
Journal:  Nat Rev Mol Cell Biol       Date:  2021-09-13       Impact factor: 94.444

3.  Native-resolution myocardial principal Eulerian strain mapping using convolutional neural networks and Tagged Magnetic Resonance Imaging.

Authors:  Inas A Yassine; Ahmed M Ghanem; Nader S Metwalli; Ahmed Hamimi; Ronald Ouwerkerk; Jatin R Matta; Michael A Solomon; Jason M Elinoff; Ahmed M Gharib; Khaled Z Abd-Elmoniem
Journal:  Comput Biol Med       Date:  2021-11-18       Impact factor: 4.589

4.  Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis.

Authors:  Ibrahim M Ibrahim; Abdo A Elfiky; Mohamed M Fathy; Sara H Mahmoud; Mahmoud ElHefnawi
Journal:  Sci Rep       Date:  2022-08-03       Impact factor: 4.996

Review 5.  Exploring Bacterial Attributes That Underpin Symbiont Life in the Monogastric Gut.

Authors:  Gerald W Tannock
Journal:  Appl Environ Microbiol       Date:  2022-08-29       Impact factor: 5.005

Review 6.  Phenotypic drug discovery: recent successes, lessons learned and new directions.

Authors:  Fabien Vincent; Arsenio Nueda; Jonathan Lee; Monica Schenone; Marco Prunotto; Mark Mercola
Journal:  Nat Rev Drug Discov       Date:  2022-05-30       Impact factor: 112.288

Review 7.  Mining genomes to illuminate the specialized chemistry of life.

Authors:  Marnix H Medema; Tristan de Rond; Bradley S Moore
Journal:  Nat Rev Genet       Date:  2021-06-03       Impact factor: 53.242

8.  A trimethoprim derivative impedes antibiotic resistance evolution.

Authors:  Madhu Sudan Manna; Yusuf Talha Tamer; Ilona Gaszek; Nicole Poulides; Ayesha Ahmed; Xiaoyu Wang; Furkan C R Toprak; DaNae R Woodard; Andrew Y Koh; Noelle S Williams; Dominika Borek; Ali Rana Atilgan; John D Hulleman; Canan Atilgan; Uttam Tambar; Erdal Toprak
Journal:  Nat Commun       Date:  2021-05-19       Impact factor: 14.919

Review 9.  Mining for novel antibiotics.

Authors:  Justin R Randall; Bryan W Davies
Journal:  Curr Opin Microbiol       Date:  2021-07-02       Impact factor: 7.584

10.  A Machine Learning Bioinformatics Method to Predict Biological Activity from Biosynthetic Gene Clusters.

Authors:  Allison S Walker; Jon Clardy
Journal:  J Chem Inf Model       Date:  2021-05-27       Impact factor: 4.956
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