Literature DB >> 34210544

Protein Amyloid Cofactors: Charged Side-Chain Arrays Meet Their Match?

Emily Lewkowicz1, Shobini Jayaraman1, Olga Gursky2.   

Abstract

Recent advances in high-resolution structural studies of protein amyloids have revealed parallel in-register cross-β-sheets with periodic arrays of closely spaced identical residues. What do these structures tell us about the mechanisms of action of common amyloid-promoting factors, such as heparan sulfate (HS), nucleic acids, polyphosphates, anionic phospholipids, and acidic pH?
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  amyloid nucleation; cross-β-sheet; electrostatic interactions; flexible docking; heparan sulfate; periodic polyanions

Mesh：

Substances：

Year:  2021        PMID： 34210544      PMCID： PMC8415129          DOI： 10.1016/j.tibs.2021.05.003

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  15 in total

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Authors:  Kazuchika Nishitsuji; Kenji Uchimura
Journal:  Glycoconj J       Date:  2017-04-11       Impact factor: 2.916

2.  Cofactors are essential constituents of stable and seeding-active tau fibrils.

Authors:  Yann Fichou; Yanxian Lin; Jennifer N Rauch; Michael Vigers; Zhikai Zeng; Madhur Srivastava; Timothy J Keller; Jack H Freed; Kenneth S Kosik; Songi Han
Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-11       Impact factor: 11.205

Review 3.  The activities of amyloids from a structural perspective.

Authors:  Roland Riek; David S Eisenberg
Journal:  Nature       Date:  2016-11-10       Impact factor: 49.962

4.  The three-dimensional structure of human β-endorphin amyloid fibrils.

Authors:  Carolin Seuring; Joeri Verasdonck; Julia Gath; Dhimam Ghosh; Nadezhda Nespovitaya; Marielle Aulikki Wälti; Samir K Maji; Riccardo Cadalbert; Peter Güntert; Beat H Meier; Roland Riek
Journal:  Nat Struct Mol Biol       Date:  2020-10-12       Impact factor: 15.369

5.  Structure-based drug design identifies polythiophenes as antiprion compounds.

Authors:  Uli S Herrmann; Anne K Schütz; Hamid Shirani; Danzhi Huang; Dino Saban; Mario Nuvolone; Bei Li; Boris Ballmer; Andreas K O Åslund; Jeffrey J Mason; Elisabeth Rushing; Herbert Budka; Sofie Nyström; Per Hammarström; Anja Böckmann; Amedeo Caflisch; Beat H Meier; K Peter R Nilsson; Simone Hornemann; Adriano Aguzzi
Journal:  Sci Transl Med       Date:  2015-08-05       Impact factor: 17.956

Review 6.  The Amyloid Phenomenon and Its Significance in Biology and Medicine.

Authors:  Christopher M Dobson; Tuomas P J Knowles; Michele Vendruscolo
Journal:  Cold Spring Harb Perspect Biol       Date:  2020-02-03       Impact factor: 10.005

Review 7.  Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis.

Authors:  Phuong H Nguyen; Ayyalusamy Ramamoorthy; Bikash R Sahoo; Jie Zheng; Peter Faller; John E Straub; Laura Dominguez; Joan-Emma Shea; Nikolay V Dokholyan; Alfonso De Simone; Buyong Ma; Ruth Nussinov; Saeed Najafi; Son Tung Ngo; Antoine Loquet; Mara Chiricotto; Pritam Ganguly; James McCarty; Mai Suan Li; Carol Hall; Yiming Wang; Yifat Miller; Simone Melchionna; Birgit Habenstein; Stepan Timr; Jiaxing Chen; Brianna Hnath; Birgit Strodel; Rakez Kayed; Sylvain Lesné; Guanghong Wei; Fabio Sterpone; Andrew J Doig; Philippe Derreumaux
Journal:  Chem Rev       Date:  2021-02-05       Impact factor: 60.622

8.  Intrinsic electronic conductivity of individual atomically resolved amyloid crystals reveals micrometer-long hole hopping via tyrosines.

Authors:  Catharine Shipps; H Ray Kelly; Peter J Dahl; Sophia M Yi; Dennis Vu; David Boyer; Calina Glynn; Michael R Sawaya; David Eisenberg; Victor S Batista; Nikhil S Malvankar
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-12       Impact factor: 11.205

9.  Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils.

Authors:  Katie L Stewart; Eleri Hughes; Edwin A Yates; David A Middleton; Sheena E Radford
Journal:  J Mol Biol       Date:  2017-07-10       Impact factor: 6.151

10.  Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee.

Authors:  Merrill D Benson; Joel N Buxbaum; David S Eisenberg; Giampaolo Merlini; Maria J M Saraiva; Yoshiki Sekijima; Jean D Sipe; Per Westermark
Journal:  Amyloid       Date:  2020-10-26       Impact factor: 7.141
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  2 in total

1.  A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation.

Authors:  Daniele Peterle; Elena S Klimtchuk; Thomas E Wales; Florian Georgescauld; Lawreen H Connors; John R Engen; Olga Gursky
Journal:  J Mol Biol       Date:  2021-10-19       Impact factor: 5.469

Review 2.  Dynamic protein structures in normal function and pathologic misfolding in systemic amyloidosis.

Authors:  Emily Lewkowicz; Olga Gursky
Journal:  Biophys Chem       Date:  2021-10-14       Impact factor: 3.628
  2 in total

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