Literature DB >> 3420417

Imaging of phosphorescence: a novel method for measuring oxygen distribution in perfused tissue.

W L Rumsey1, J M Vanderkooi, D F Wilson.   

Abstract

The imaging of phosphorescence provides a method for monitoring oxygen distribution within the vascular system of intact tissues. Isolated rat lives were perfused through the portal vein with media containing palladium coproporphyrin, which phosphoresced and was used to image the liver at various perfusion rates. Because oxygen is a powerful quenching agent for phosphors, the transition from well-perfused liver to anoxia (no flow of oxygen) resulted in large increases of phosphorescence. During stepwise restoration of oxygen flow, the phosphorescence images showed marked heterogeneous patterns of tissue reoxygenation, which indicated that there were regional inequalities in oxygen delivery.

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Year:  1988        PMID： 3420417     DOI： 10.1126/science.3420417

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  135 in total

1.  Long-term optical imaging and spectroscopy reveal mechanisms underlying the intrinsic signal and stability of cortical maps in V1 of behaving monkeys.

Authors:  E Shtoyerman; A Arieli; H Slovin; I Vanzetta; A Grinvald
Journal:  J Neurosci       Date:  2000-11-01       Impact factor: 6.167

2.  Generation of phosphorescent triplet states via photoinduced electron transfer: energy and electron transfer dynamics in Pt porphyrin-Rhodamine B dyads.

Authors:  Tomoyasu Mani; Dariusz M Niedzwiedzki; Sergei A Vinogradov
Journal:  J Phys Chem A       Date:  2012-03-30       Impact factor: 2.781

3.  Fluorescence lifetime imaging.

Authors:  J R Lakowicz; H Szmacinski; K Nowaczyk; K W Berndt; M Johnson
Journal:  Anal Biochem       Date:  1992-05-01       Impact factor: 3.365

Review 4.  Frontiers in optical imaging of cerebral blood flow and metabolism.

Authors:  Anna Devor; Sava Sakadžić; Vivek J Srinivasan; Mohammad A Yaseen; Krystal Nizar; Payam A Saisan; Peifang Tian; Anders M Dale; Sergei A Vinogradov; Maria Angela Franceschini; David A Boas
Journal:  J Cereb Blood Flow Metab       Date:  2012-01-18       Impact factor: 6.200

Review 5.  Dynamics of muscle microcirculatory and blood-myocyte O(2) flux during contractions.

Authors:  D C Poole; S W Copp; D M Hirai; T I Musch
Journal:  Acta Physiol (Oxf)       Date:  2011-03-01       Impact factor: 6.311

6.  Effect of hemorrhagic hypotension on cortical oxygen pressure and striatal extracellular dopamine in cat brain.

Authors:  D Song; J Marczis; M Olano; A G Kovach; D Wilson; A Pastuszko
Journal:  Neurochem Res       Date:  1997-09       Impact factor: 3.996

Review 7.  In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance.

Authors:  Boris Epel; Howard J Halpern
Journal:  Methods Enzymol       Date:  2015-09-26       Impact factor: 1.600

Review 8.  Measuring and regulating oxygen levels in microphysiological systems: design, material, and sensor considerations.

Authors:  Kristina R Rivera; Murat A Yokus; Patrick D Erb; Vladimir A Pozdin; Michael Daniele
Journal:  Analyst       Date:  2019-05-13       Impact factor: 4.616

9.  Phosphorescent oxygen sensor with dendritic protection and two-photon absorbing antenna.

Authors:  Raymond P Briñas; Thomas Troxler; Robin M Hochstrasser; Sergei A Vinogradov
Journal:  J Am Chem Soc       Date:  2005-08-24       Impact factor: 15.419

10.  Oxymetry deep in tissues with low-frequency electron paramagnetic resonance.

Authors:  H J Halpern; C Yu; M Peric; E Barth; D J Grdina; B A Teicher
Journal:  Proc Natl Acad Sci U S A       Date:  1994-12-20       Impact factor: 11.205
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