Literature DB >> 34201480

Epileptic Seizure Detection on an Ultra-Low-Power Embedded RISC-V Processor Using a Convolutional Neural Network.

Andreas Bahr1, Matthias Schneider1, Maria Avitha Francis1, Hendrik M Lehmann2, Igor Barg3, Anna-Sophia Buschhoff4, Peer Wulff4, Thomas Strunskus3, Franz Faupel3.   

Abstract

The treatment of refractory epilepsy via closed-loop implantable devices that act on seizures either by drug release or electrostimulation is a highly attractive option. For such implantable medical devices, efficient and low energy consumption, small size, and efficient processing architectures are essential. To meet these requirements, epileptic seizure detection by analysis and classification of brain signals with a convolutional neural network (CNN) is an attractive approach. This work presents a CNN for epileptic seizure detection capable of running on an ultra-low-power microprocessor. The CNN is implemented and optimized in MATLAB. In addition, the CNN is also implemented on a GAP8 microprocessor with RISC-V architecture. The training, optimization, and evaluation of the proposed CNN are based on the CHB-MIT dataset. The CNN reaches a median sensitivity of 90% and a very high specificity over 99% corresponding to a median false positive rate of 6.8 s per hour. After implementation of the CNN on the microcontroller, a sensitivity of 85% is reached. The classification of 1 s of EEG data takes t=35 ms and consumes an average power of P≈140 μW. The proposed detector outperforms related approaches in terms of power consumption by a factor of 6. The universal applicability of the proposed CNN based detector is verified with recording of epileptic rats. This results enable the design of future medical devices for epilepsy treatment.

Entities:  

Keywords:  EEG; RISC-V; convolutional neural network; epileptic seizure detection; ultra-low-power

Mesh:

Year:  2021        PMID: 34201480      PMCID: PMC8301882          DOI: 10.3390/bios11070203

Source DB:  PubMed          Journal:  Biosensors (Basel)        ISSN: 2079-6374


  17 in total

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Authors:  Stewart J Thomas; Reid R Harrison; Anthony Leonardo; Matthew S Reynolds
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2.  Seizure Prediction in Scalp EEG Using 3D Convolutional Neural Networks With an Image-Based Approach.

Authors:  Ahmet Remzi Ozcan; Sarp Erturk
Journal:  IEEE Trans Neural Syst Rehabil Eng       Date:  2019-09-25       Impact factor: 3.802

3.  Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs: A 30-Year Longitudinal Cohort Study.

Authors:  Zhibin Chen; Martin J Brodie; Danny Liew; Patrick Kwan
Journal:  JAMA Neurol       Date:  2018-03-01       Impact factor: 18.302

Review 4.  Seizure detection using scalp-EEG.

Authors:  Christoph Baumgartner; Johannes P Koren
Journal:  Epilepsia       Date:  2018-06       Impact factor: 5.864

5.  Automated seizure detection using a self-organizing neural network.

Authors:  A J Gabor; R R Leach; F U Dowla
Journal:  Electroencephalogr Clin Neurophysiol       Date:  1996-09

6.  Crowdsourcing seizure detection: algorithm development and validation on human implanted device recordings.

Authors:  Steven N Baldassano; Benjamin H Brinkmann; Hoameng Ung; Tyler Blevins; Erin C Conrad; Kent Leyde; Mark J Cook; Ankit N Khambhati; Joost B Wagenaar; Gregory A Worrell; Brian Litt
Journal:  Brain       Date:  2017-06-01       Impact factor: 13.501

Review 7.  The consequences of uncontrolled epilepsy.

Authors:  Michael R Sperling
Journal:  CNS Spectr       Date:  2004-02       Impact factor: 3.790

8.  An exoskeleton controlled by an epidural wireless brain-machine interface in a tetraplegic patient: a proof-of-concept demonstration.

Authors:  Alim Louis Benabid; Thomas Costecalde; Andrey Eliseyev; Guillaume Charvet; Alexandre Verney; Serpil Karakas; Michael Foerster; Aurélien Lambert; Boris Morinière; Neil Abroug; Marie-Caroline Schaeffer; Alexandre Moly; Fabien Sauter-Starace; David Ratel; Cecile Moro; Napoleon Torres-Martinez; Lilia Langar; Manuela Oddoux; Mircea Polosan; Stephane Pezzani; Vincent Auboiroux; Tetiana Aksenova; Corinne Mestais; Stephan Chabardes
Journal:  Lancet Neurol       Date:  2019-10-03       Impact factor: 44.182

9.  The impact of epilepsy on quality of life: a qualitative analysis.

Authors:  Malachy Bishop; Chase A Allen
Journal:  Epilepsy Behav       Date:  2003-06       Impact factor: 2.937

10.  Bispectrum and Recurrent Neural Networks: Improved Classification of Interictal and Preictal States.

Authors:  Laura Gagliano; Elie Bou Assi; Dang K Nguyen; Mohamad Sawan
Journal:  Sci Rep       Date:  2019-10-30       Impact factor: 4.379

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  1 in total

1.  Intelligent Biosignal Processing in Wearable and Implantable Sensors.

Authors:  Hariton-Nicolae Costin; Saeid Sanei
Journal:  Biosensors (Basel)       Date:  2022-06-09
  1 in total

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