Literature DB >> 34191222

A clinical case series of COVID-19-associated acute limb ischemia: real-world situation.

Steven Philip Surya1, Rony Marethianto Santoso2.   

Abstract

BACKGROUND: COVID-19 was a trending topic all year long in 2020. Currently, it is not only a problem for a pulmonologist since it could cause complications to many other organs, including the cardiovascular system. Recent acute COVID-19 infection state has been associated with hypercoagulation and causing microthrombi called immunothrombus. Acute limb ischemia is one of the rare complications but organ-threatening. Unfortunately, unlike coronary artery disease, there is no recent guideline for cardiologists to diagnose and manage acute limb ischemia in pandemic situations CASE
PRESENTATION: This case series presented two patients with acute limb injury (ALI)-complicating COVID-19, with chief complaints of pain at their lower extremity. The first patient was an 80-year-old woman who was just dismissed from the hospital due to COVID-19. The distal part of her toe was cyanosed, and her motoric and sensory functions were partially reduced. She was treated with oral drug therapy due to unwillingness to be hospitalized. Interestingly, she had recovered by using oral drug therapy. The second case was a 54-years-old female with several comorbidities such as obesity, type 2 diabetes mellitus, hypertension, dyslipidemia, and chronic obstructive pulmonary disease. She had cyanosed foot and weak arterial pulsation. Unfortunately, she passed away due to acute respiratory distress syndrome.
CONCLUSION: Several internal and external factors cause ALI treatment to be more challenging in the pandemic COVID-19 situation. The diagnosis and management of ALI in COVID-19 patients may not fully comply with the current guideline and are likely to be affected by local hospital regulations. Clinical follow-up might be an essential feature in treating ALI in COVID-19 patients.

Entities:  

Keywords:  Acute limb ischemia; COVID-19; COVID-19-associated coagulopathy; Case report; Immunothrombus

Year:  2021        PMID: 34191222     DOI: 10.1186/s43044-021-00187-0

Source DB:  PubMed          Journal:  Egypt Heart J        ISSN: 1110-2608


  12 in total

1.  Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.

Authors:  Torsten G Loof; Matthias Mörgelin; Linda Johansson; Sonja Oehmcke; Anders I Olin; Gerhard Dickneite; Anna Norrby-Teglund; Ulrich Theopold; Heiko Herwald
Journal:  Blood       Date:  2011-05-25       Impact factor: 22.113

2.  Editor's Choice - European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Acute Limb Ischaemia.

Authors:  Martin Björck; Jonothan J Earnshaw; Stefan Acosta; Frederico Bastos Gonçalves; Frederic Cochennec; E S Debus; Robert Hinchliffe; Vincent Jongkind; Mark J W Koelemay; Gabor Menyhei; Alexei V Svetlikov; Yamume Tshomba; Jos C Van Den Berg; Gert J de Borst; Nabil Chakfé; Stavros K Kakkos; Igor Koncar; Jes S Lindholt; Riikka Tulamo; Melina Vega de Ceniga; Frank Vermassen; Jonathan R Boyle; Kevin Mani; Nobuyoshi Azuma; Edward T C Choke; Tina U Cohnert; Robert A Fitridge; Thomas L Forbes; Mohamad S Hamady; Alberto Munoz; Stefan Müller-Hülsbeck; Kumud Rai
Journal:  Eur J Vasc Endovasc Surg       Date:  2019-12-31       Impact factor: 7.069

Review 3.  2016 AHA/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

Authors:  Marie D Gerhard-Herman; Heather L Gornik; Coletta Barrett; Neal R Barshes; Matthew A Corriere; Douglas E Drachman; Lee A Fleisher; Francis Gerry R Fowkes; Naomi M Hamburg; Scott Kinlay; Robert Lookstein; Sanjay Misra; Leila Mureebe; Jeffrey W Olin; Rajan A G Patel; Judith G Regensteiner; Andres Schanzer; Mehdi H Shishehbor; Kerry J Stewart; Diane Treat-Jacobson; M Eileen Walsh
Journal:  Circulation       Date:  2016-11-13       Impact factor: 29.690

4.  Acute Pulmonary Embolism Associated with COVID-19 Pneumonia Detected with Pulmonary CT Angiography.

Authors:  Franck Grillet; Julien Behr; Paul Calame; Sébastien Aubry; Eric Delabrousse
Journal:  Radiology       Date:  2020-04-23       Impact factor: 11.105

5.  The COVID-19 Pandemic: Public Health and Epidemiology.

Authors:  Colin Binns; Wah Yun Low; Lee Mi Kyung
Journal:  Asia Pac J Public Health       Date:  2020-05-19       Impact factor: 1.399

6.  Acute limb ischemia in patients with COVID-19 pneumonia.

Authors:  Raffaello Bellosta; Luca Luzzani; Giuseppe Natalini; Matteo Alberto Pegorer; Luca Attisani; Luisa Giuseppina Cossu; Camillo Ferrandina; Alessandro Fossati; Elena Conti; Ruth L Bush; Gabriele Piffaretti
Journal:  J Vasc Surg       Date:  2020-04-29       Impact factor: 4.268

Review 7.  COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.

Authors:  Masataka Nishiga; Dao Wen Wang; Yaling Han; David B Lewis; Joseph C Wu
Journal:  Nat Rev Cardiol       Date:  2020-07-20       Impact factor: 32.419

8.  Lower-extremity Arterial Thrombosis Associated with COVID-19 Is Characterized by Greater Thrombus Burden and Increased Rate of Amputation and Death.

Authors:  Inessa A Goldman; Kenny Ye; Meir H Scheinfeld
Journal:  Radiology       Date:  2020-07-16       Impact factor: 11.105

9.  Incidence of thrombotic complications in critically ill ICU patients with COVID-19.

Authors:  F A Klok; M J H A Kruip; N J M van der Meer; M S Arbous; D A M P J Gommers; K M Kant; F H J Kaptein; J van Paassen; M A M Stals; M V Huisman; H Endeman
Journal:  Thromb Res       Date:  2020-04-10       Impact factor: 3.944

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