C Atkin1, V Kamwa1, V Reddy-Kolanu2, D Parekh3, F Evison4, P Nightingale5, S Gallier6, S Ball7, E Sapey8. 1. Acute Medicine, Birmingham Acute Care Research Group, Institute of Inflammation and Ageing. 2. Acute Medicine, University Hospitals Birmingham NHS Foundation Trust. 3. A. Intensive Care Medicine, University Hospitals Birmingham NHS Foundation Trust. 4. Research Analytics, Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust. 5. NIHR Clinical Research Facility Statistician, University Hospitals Birmingham NHS Foundation Trust. 6. PIONEER Technical Director, Lead for Research Analytics Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust. 7. A. Chief Medical Officer, University Hospitals Birmingham NHS Foundation Trust. 8. A. Director of PIONEER: Health Data Research UK (HDRUK) Health Data Research Hub for Acute Care B. Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham.
Abstract
BACKGROUND: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus. METHODS: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days. RESULTS: Wave 2 patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions. CONCLUSION: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.
BACKGROUND: This study assesses COVID-19 hospitalised patient demography and outcomes during wave 1 and wave 2, prior to new variants of the virus. METHODS: All patients with a positive SARS-CoV-2 swab between 10th March 2020 and 5th July 2020 (wave 1) and 1st September 2020 and 16th November 2020 (wave 2) admitted to University Hospitals Birmingham NHS Foundation Trust were included (n=4856), followed for 28 days. RESULTS:Wave 2patients were younger, more ethnically diverse, had less co-morbidities and disease presentation was milder on presentation. After matching for these factors, mortality was reduced, but without differences in intensive care admissions. CONCLUSION: Prior to new SARS-CoV-2 variants, outcomes for hospitalised patients with COVID-19 were improving but with similar intensive care needs.
Authors: David Fluck; Suzanne Rankin; Andrea Lewis; Jonathan Robin; Jacqui Rees; Jo Finch; Yvonne Jones; Gareth Jones; Kevin Kelly; Paul Murray; Michael Wood; Christopher Henry Fry; Thang Sieu Han Journal: Intern Emerg Med Date: 2021-10-12 Impact factor: 5.472