Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization.

× No keyword cloud information.

8 in total

1. A rapid assay for epoxide hydratase activity with benzo (a)pyrene 4,5-(K-region)-oxide as substrate.

Authors: H U Schmassmann; H R Glatt; F Oesch
Journal: Anal Biochem Date: 1976-07 Impact factor: 3.365

2. Dual role of epoxide hydratase in both activation and inactivation of benzo(a)pyrene.

Authors: P Bentley; F Oesch; H Glatt
Journal: Arch Toxicol Date: 1977-12-30 Impact factor: 5.153

3. An improved bacterial test system for the detection and classification of mutagens and carcinogens.

Authors: B N Ames; F D Lee; W E Durston
Journal: Proc Natl Acad Sci U S A Date: 1973-03 Impact factor: 11.205

4. A facile synthesis of arene oxides at the K regions of polycylic hydrocarbons.

Authors: P Dansette; D M Jerina
Journal: J Am Chem Soc Date: 1974-02-20 Impact factor: 15.419

Review 5. The role of glutathione and glutathione S-transferases in mercapturic acid biosynthesis.

Authors: E Boyland; L F Chasseaud
Journal: Adv Enzymol Relat Areas Mol Biol Date: 1969

6. Purification and specificity of a human microsomal epoxide hydratase.

Authors: F Oesch
Journal: Biochem J Date: 1974-04 Impact factor: 3.857

7. Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection.

Authors: B N Ames; W E Durston; E Yamasaki; F D Lee
Journal: Proc Natl Acad Sci U S A Date: 1973-08 Impact factor: 11.205

8. Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. A general assay and kinetic properties.

Authors: P Bentley; H Schmassmann; P Sims; F Oesch
Journal: Eur J Biochem Date: 1976-10-01

8 in total

10 in total

1. Species differences in activating and inactivating enzymes related to the control of mutagenic metabolites.

Authors: F Oesch; D Raphael; H Schwind; H R Glatt
Journal: Arch Toxicol Date: 1977-12-30 Impact factor: 5.153

2. Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia.

Authors: Matthew L Edin; Behin Gholipour Hamedani; Artiom Gruzdev; Joan P Graves; Fred B Lih; Samuel J Arbes; Rohanit Singh; Anette C Orjuela Leon; J Alyce Bradbury; Laura M DeGraff; Samantha L Hoopes; Michael Arand; Darryl C Zeldin
Journal: J Biol Chem Date: 2018-01-03 Impact factor: 5.157

3. Bioactivation of dapsone to a cytotoxic metabolite: in vitro use of a novel two compartment system which contains human tissues.

Authors: R J Riley; P Roberts; M D Coleman; N R Kitteringham; B K Park
Journal: Br J Clin Pharmacol Date: 1990-09 Impact factor: 4.335

4. Cytosolic epoxide hydrolase in fetal and adult human liver.

Authors: G M Pacifici; C Colizzi; L Giuliani; A Rane
Journal: Arch Toxicol Date: 1983-12 Impact factor: 5.153

5. Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.

Authors: A Viviani; A von Däniken; C Schlatter; W K Lutz
Journal: J Cancer Res Clin Oncol Date: 1980 Impact factor: 4.553

6. Purification and characterization of a new cytosolic glutathione S-transferase (glutathione S-transferase X) from rat liver.

Authors: T Friedberg; U Milbert; P Bentley; T M Guenther; F Oesch
Journal: Biochem J Date: 1983-12-01 Impact factor: 3.857

Inactivation of electrophilic metabolites by glutathione S-transferases and limitation of the system due to subcellular localization.