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Literature DB >> 34179285

Microbial Mutagenicity Assay: Ames Test.

Urvashi Vijay¹, Sonal Gupta², Priyanka Mathur¹, Prashanth Suravajhala², Pradeep Bhatnagar¹.

Abstract

The Microbial mutagenicity Ames test is a bacterial bioassay accomplished in vitro to evaluate the mutagenicity of various environmental carcinogens and toxins. While Ames test is used to identify the revert mutations which are present in strains, it can also be used to detect the mutagenicity of environmental samples such as drugs, dyes, reagents, cosmetics, waste water, pesticides and other substances which are easily solubilized in a liquid suspension. We present the protocol for conducting Ames test in the laboratory.

Entities: Chemical

Keywords: Carcinogenicity; Gene mutation; Mutagenicity; Revertants; Salmonella strains

Year: 2018 PMID： 34179285 PMCID： PMC8203972 DOI： 10.21769/BioProtoc.2763

Source DB: PubMed Journal: Bio Protoc ISSN： 2331-8325

24 in total

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Journal: Mutat Res Date: 2000-01-03 Impact factor: 2.433

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Authors: J McCann; E Choi; E Yamasaki; B N Ames
Journal: Proc Natl Acad Sci U S A Date: 1975-12 Impact factor: 11.205

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Authors: B N Ames; F D Lee; W E Durston
Journal: Proc Natl Acad Sci U S A Date: 1973-03 Impact factor: 11.205

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Journal: Cancer Res Date: 1972-10 Impact factor: 12.701

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Authors: D E Levin; E Yamasaki; B N Ames
Journal: Mutat Res Date: 1982-06 Impact factor: 2.433

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Authors: L Bernstein; J Kaldor; J McCann; M C Pike
Journal: Mutat Res Date: 1982-08 Impact factor: 2.433

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Authors: D Maron; J Katzenellenbogen; B N Ames
Journal: Mutat Res Date: 1981-04 Impact factor: 2.433

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Authors: G C Walker; P P Dobson
Journal: Mol Gen Genet Date: 1979-04-17

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Authors: W G Shanabruch; G C Walker
Journal: Mol Gen Genet Date: 1980

10. The development of anaerobic methods for bacterial mutation assays: aerobic and anaerobic fluctuation tests of human faecal extracts and reference mutagens.

Authors: S Venitt; D Bosworth
Journal: Carcinogenesis Date: 1983 Impact factor: 4.944

4 in total

4. Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP-2 inhibitors targeting breast cancer.

Authors: Nadeen M El-Ghobashy; Selwan M El-Sayed; Ihsan A Shehata; Mahmoud B El-Ashmawy
Journal: Sci Rep Date: 2022-09-28 Impact factor: 4.996