Literature DB >> 3416994

Hypothalamo-hypophyseal-gonadal function in the rat following administration of the novel and selective D-1 agonist CY 208-243.

R A Siegel1, M Markó.   

Abstract

The effects of the novel and selective dopamine D-1 agonist CY 208-243 on the rat hypothalamo-hypophyseal-gonadal (HHG) axis were studied. CY 208-243 did not modify the concentration of luteinizing hormone (LH) in serum from female or male rats, and had no effect upon opiate antagonist-induced stimulation of LH secretion in male rats. CY 208-243 did not inhibit ovulation in cycling female rats. Thus, D-1 receptor activation by systemic drug administration does not alter HHG function in rats.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3416994     DOI： 10.1007/BF01959157

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Effects of naloxone, morphine and methionine enkephalin on serum prolactin, luteinizing hormone, follicle stimulating hormone, thyroid stimulating hormone and growth hormone.

Authors:  J F Bruni; D Van Vugt; S Marshall; J Meites
Journal:  Life Sci       Date:  1977-08-01       Impact factor: 5.037

2.  Inhibition of spontaneous and induced ovulation in rats by non-steroidal agents.

Authors:  M Markó; E Flückiger
Journal:  Experientia       Date:  1974-10-15

3.  Evidence for the existence of a dopamine receptor of the D-1 type in the rat median eminence.

Authors:  K Fuxe; L F Agnati; F Benfenati; K Andersson; M Camurri; M Zoli
Journal:  Neurosci Lett       Date:  1983-12-30       Impact factor: 3.046

4.  Opioid peptides modulate luteinizing hormone secretion during sexual maturation.

Authors:  M S Blank; A E Panerai; H G Friesen
Journal:  Science       Date:  1979-03-16       Impact factor: 47.728

5.  Dopaminergic neurones in the zona incerta exert a stimulatory control on gonadotrophin release via D1 dopamine receptors.

Authors:  M D James; F J MacKenzie; P A Tuohy-Jones; C A Wilson
Journal:  Neuroendocrinology       Date:  1987-05       Impact factor: 4.914

6.  Role of serotonin in the regulation of ovulation. Evidence from pharmacological studies.

Authors:  M Markó; E Flückiger
Journal:  Neuroendocrinology       Date:  1980-04       Impact factor: 4.914

7.  Relation of gonadal hormones to differential LH response to naloxone in prepubertal male and female rats.

Authors:  P W Sylvester; D K Sarkar; K P Briski; J Meites
Journal:  Neuroendocrinology       Date:  1985-02       Impact factor: 4.914

8.  Regulation of luteinizing hormone secretion in prepubertal male and female rats.

Authors:  R Schulz; A Wilhelm; K M Pirke; A Herz
Journal:  Life Sci       Date:  1982 Nov 15-22       Impact factor: 5.037

9.  Dopamine-stimulated adenylate cyclase in hypothalamus: influence of estrous cycle in female and castration in male rats.

Authors:  G A Barr; H S Ahn; M H Makman
Journal:  Brain Res       Date:  1983-10-31       Impact factor: 3.252

10.  Inhibitory effect of a new opioid agonist on reproductive endocrine activity in rats of both sexes.

Authors:  M Markó; D Römer
Journal:  Life Sci       Date:  1983-07-18       Impact factor: 5.037
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.