Literature DB >> 34169646

A conditional female lethal system for genetic suppression of the global fruit crop pest Drosophila suzukii.

Fang Li1, Akihiko Yamamoto1, Esther J Belikoff1, Amy Berger1, Emily H Griffith2, Maxwell J Scott1.   

Abstract

BACKGROUND: Drosophila suzukii (Matsumura, 1931, Diptera: Drosophilidae) is a global pest of soft-skinned fruits such as blueberries, cherries and raspberries. Also known as spotted-wing drosophila, D. suzukii is native to Asia but is now widely distributed in the Americas and Europe and presents a serious challenge for growers. Genetic control strategies offer an environmentally-friendly approach for control of D. suzukii.
RESULTS: In this study we have developed transgenic strains of D. suzukii that carry dominant conditional female lethal transgenes. When raised in the absence of tetracycline, female D. suzukii die. We show that repeated releases of an excess of transgenic males can suppress D. suzukii populations in laboratory cage trials.
CONCLUSION: Our data suggests that the transgenic strain could provide an effective approach for control of this invasive pest of soft-skinned fruits. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

Entities:  

Keywords:  Drosophila suzukii; alternate splicing; fsRIDL; spotted wing Drosophila; sterile insect technique; tet-OFF

Year:  2021        PMID: 34169646     DOI: 10.1002/ps.6530

Source DB:  PubMed          Journal:  Pest Manag Sci        ISSN: 1526-498X            Impact factor:   4.845


  2 in total

1.  Evaluation of Additional Drosophila suzukii Male-Only Strains Generated Through Remobilization of an FL19 Transgene.

Authors:  Akihiko Yamamoto; Amarish K Yadav; Maxwell J Scott
Journal:  Front Bioeng Biotechnol       Date:  2022-03-15

2.  Partial masculinization of Aedes aegypti females by conditional expression of Nix.

Authors:  Bianca B Kojin; Emma Jakes; James K Biedler; Zhijian Tu; Zach N Adelman
Journal:  PLoS Negl Trop Dis       Date:  2022-07-01
  2 in total

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