Literature DB >> 34168118

Cellular and metabolic mechanisms of nutrient actions in immune function.

Philip Newsholme1.   

Abstract

Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.

Entities:  

Year:  2021        PMID: 34168118     DOI: 10.1038/s41387-021-00162-3

Source DB:  PubMed          Journal:  Nutr Diabetes        ISSN: 2044-4052            Impact factor:   5.097


  16 in total

Review 1.  Monocyte and macrophage heterogeneity.

Authors:  Siamon Gordon; Philip R Taylor
Journal:  Nat Rev Immunol       Date:  2005-12       Impact factor: 53.106

Review 2.  Macrophage activation and polarization.

Authors:  Fernando Oneissi Martinez; Antonio Sica; Alberto Mantovani; Massimo Locati
Journal:  Front Biosci       Date:  2008-01-01

Review 3.  Mitochondria are the powerhouses of immunity.

Authors:  Evanna L Mills; Beth Kelly; Luke A J O'Neill
Journal:  Nat Immunol       Date:  2017-04-18       Impact factor: 25.606

Review 4.  Regulative potential of glutamine--relation to glutathione metabolism.

Authors:  Erich Roth; Rudolf Oehler; Nicole Manhart; Ruth Exner; Barbara Wessner; Eva Strasser; Andreas Spittler
Journal:  Nutrition       Date:  2002-03       Impact factor: 4.008

Review 5.  Molecular mechanisms of glutamine action.

Authors:  R Curi; C J Lagranha; S Q Doi; D F Sellitti; J Procopio; T C Pithon-Curi; M Corless; P Newsholme
Journal:  J Cell Physiol       Date:  2005-08       Impact factor: 6.384

Review 6.  Alternative activation of macrophages: mechanism and functions.

Authors:  Siamon Gordon; Fernando O Martinez
Journal:  Immunity       Date:  2010-05-28       Impact factor: 31.745

7.  Glutamine supplementation further enhances exercise-induced plasma IL-6.

Authors:  N Hiscock; E W Petersen; K Krzywkowski; J Boza; J Halkjaer-Kristensen; B K Pedersen
Journal:  J Appl Physiol (1985)       Date:  2003-02-28

Review 8.  Glutamine-dependent changes in gene expression and protein activity.

Authors:  R Curi; C J Lagranha; S Q Doi; D F Sellitti; J Procopio; T C Pithon-Curi
Journal:  Cell Biochem Funct       Date:  2005 Mar-Apr       Impact factor: 3.685

9.  THE METABOLISM OF TUMORS IN THE BODY.

Authors:  O Warburg; F Wind; E Negelein
Journal:  J Gen Physiol       Date:  1927-03-07       Impact factor: 4.086

Review 10.  Nutritional Modulation of Immune Function: Analysis of Evidence, Mechanisms, and Clinical Relevance.

Authors:  Dayong Wu; Erin D Lewis; Munyong Pae; Simin Nikbin Meydani
Journal:  Front Immunol       Date:  2019-01-15       Impact factor: 7.561

View more
  2 in total

Review 1.  Sirtuins are crucial regulators of T cell metabolism and functions.

Authors:  Imene Hamaidi; Sungjune Kim
Journal:  Exp Mol Med       Date:  2022-03-16       Impact factor: 12.153

2.  The Effect of Different Nutritional Nursing Support on the Nutritional Status and Disease Recovery of Elderly Patients with Gastrointestinal Tumors during the Perioperative Period.

Authors:  Lingzhi Chen; Sixin Zheng; Qi Xie; Liping Huang; Guang Yin
Journal:  Comput Math Methods Med       Date:  2022-06-29       Impact factor: 2.809

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.