Diyar Saeed1,2, Evgenij Potapov3,4, Antonio Loforte5, Michiel Morshuis6, David Schibilsky7, Daniel Zimpfer8, Julia Riebandt8, Federico Pappalardo9, Matteo Attisani10, Mauro Rinaldi10, Davide Pacini5, Assad Haneya11, Faiz Ramjankhan12, Dirk W Donker12, Ulrich P Jorde13, Wolfgang Otto1, Julia Stein3, Dmytro Tsyganenko3, Ameen Al-Naamani1, Radi Wieloch2, Rafael Ayala7, Jochen Cremer11, Michael Borger1, Artur Lichtenberg2, Jan Gummert6. 1. Department of Cardiac surgery, Leipzig Heart Center, Leipzig, Germany. 2. Department for Cardiac Surgery, Duesseldorf University Hospital, Duesseldorf, Germany. 3. Department of Cardiac Surgery, German Heart Center Berlin, Berlin, Germany. 4. DZHK (German Center for Cardiovascular Research), Partner Site Berlin, Berlin, Germany. 5. Division of Cardiac Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy. 6. Department of Cardiovascular and Thoracic Surgery, Heart and diabetes Center NRW, Bad Oeynhausen, Germany. 7. Department of Cardiac and Vascular Surgery, Freiburg University, Freiburg, Germany. 8. Department of Cardiac Surgery, Medical University Vienna, Vienna, Austria. 9. Advanced Heart Failure and Mechanical Circulatory Support Program, San Raffaele Hospital, Vita Salute University, Milan, Italy. 10. Department of Cardiac Surgery, University of Turin, Turin, Italy. 11. Department of Cardiac Surgery, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany. 12. Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, The Netherland. 13. Department of Medicine, Montefiore Medical Center, Bronx, NY, USA.
Abstract
BACKGROUND: The literature on outcomes of patients requiring durable mechanical circulatory support (MCS) after extra-corporeal life support (ECLS) is limited. The aim of this study was to investigate the impact of preoperative ECLS cannulation on postoperative outcome after durable MCS implantation. METHODS: The durable MCS after ECLS registry is a multicenter retrospective study that gathered data on consecutive patients who underwent durable MCS implantation after ECLS between January 2010 and August 2018 in eleven high volume European centers. Patients who underwent the implantation of total artificial heart, pulsatile pumps, or first-generation pumps after ECLS were excluded from the analysis. The remaining patients were divided into two groups; central ECLS group (cECLS) and peripheral ECLS group (pECLS). A 1:1 propensity score analysis was performed to identify two matched groups. The outcome of these two groups was compared. RESULTS: A total of 531 durable MCS after ECLS were implanted during this period. The ECLS cannulation site was peripheral in 87% (n=462) and central in 13% (n=69) of the patients. After excluding pulsatile pumps and total artificial heart patients, a total of 494 patients remained (pECLS =434 patients, cECLS =60 patients). A 1:1 propensity score analysis resulted in 2 matched groups (each 55 patients) with median age of 54 years (48-60 years) in cECLS group and 54 years (43-60 years) in pECLS group. HeartWare HVAD (Medtronic, Minneapolis, MN) was implanted in the majority of the patients (cECLS =71% vs. pECLS =76%, P=0.67). All postoperative morbidities were comparable between the groups. The thirty-day, one year and long-term survival was comparable between the groups (P=0.73). CONCLUSIONS: The cannulation strategy of ECLS appears to have no impact on the post-operative outcome after durable MCS implantation. 2021 Annals of Cardiothoracic Surgery. All rights reserved.
BACKGROUND: The literature on outcomes of patients requiring durable mechanical circulatory support (MCS) after extra-corporeal life support (ECLS) is limited. The aim of this study was to investigate the impact of preoperative ECLS cannulation on postoperative outcome after durable MCS implantation. METHODS: The durable MCS after ECLS registry is a multicenter retrospective study that gathered data on consecutive patients who underwent durable MCS implantation after ECLS between January 2010 and August 2018 in eleven high volume European centers. Patients who underwent the implantation of total artificial heart, pulsatile pumps, or first-generation pumps after ECLS were excluded from the analysis. The remaining patients were divided into two groups; central ECLS group (cECLS) and peripheral ECLS group (pECLS). A 1:1 propensity score analysis was performed to identify two matched groups. The outcome of these two groups was compared. RESULTS: A total of 531 durable MCS after ECLS were implanted during this period. The ECLS cannulation site was peripheral in 87% (n=462) and central in 13% (n=69) of the patients. After excluding pulsatile pumps and total artificial heart patients, a total of 494 patients remained (pECLS =434 patients, cECLS =60 patients). A 1:1 propensity score analysis resulted in 2 matched groups (each 55 patients) with median age of 54 years (48-60 years) in cECLS group and 54 years (43-60 years) in pECLS group. HeartWare HVAD (Medtronic, Minneapolis, MN) was implanted in the majority of the patients (cECLS =71% vs. pECLS =76%, P=0.67). All postoperative morbidities were comparable between the groups. The thirty-day, one year and long-term survival was comparable between the groups (P=0.73). CONCLUSIONS: The cannulation strategy of ECLS appears to have no impact on the post-operative outcome after durable MCS implantation. 2021 Annals of Cardiothoracic Surgery. All rights reserved.
Entities:
Keywords:
Mechanical circulatory support (MCS); cannulation strategy; extra-corporeal life support (ECLS); outcome; ventricular assist device
Authors: Eduardo Barge-Caballero; Luis Almenar-Bonet; Francisco Gonzalez-Vilchez; José L Lambert-Rodríguez; José González-Costello; Javier Segovia-Cubero; María A Castel-Lavilla; Juan Delgado-Jiménez; Iris P Garrido-Bravo; Diego Rangel-Sousa; Manuel Martínez-Sellés; Luis De la Fuente-Galan; Gregorio Rábago-Juan-Aracil; Marisa Sanz-Julve; Daniela Hervás-Sotomayor; Sonia Mirabet-Pérez; Javier Muñiz; Maria G Crespo-Leiro Journal: Eur J Heart Fail Date: 2017-09-26 Impact factor: 15.534
Authors: David N Ranney; Ehsan Benrashid; James M Meza; Jeffrey E Keenan; Desiree K Bonadonna; Raquel Bartz; Carmelo A Milano; Matthew G Hartwig; John C Haney; Jacob N Schroder; Mani A Daneshmand Journal: Semin Thorac Cardiovasc Surg Date: 2017-02-20
Authors: Joel B Durinka; Linda J Bogar; Hitoshi Hirose; Chris Brehm; Michael M Koerner; Walter E Pae; Aly El-Banayosy; Edward R Stephenson; Nicholas C Cavarocchi Journal: ASAIO J Date: 2014 Mar-Apr Impact factor: 2.872
Authors: Giovanni Mariscalco; Antonio Salsano; Antonio Fiore; Magnus Dalén; Vito G Ruggieri; Diyar Saeed; Kristján Jónsson; Giuseppe Gatti; Svante Zipfel; Angelo M Dell'Aquila; Andrea Perrotti; Antonio Loforte; Ugolino Livi; Marek Pol; Cristiano Spadaccio; Matteo Pettinari; Sigurdur Ragnarsson; Khalid Alkhamees; Zein El-Dean; Karl Bounader; Fausto Biancari Journal: J Thorac Cardiovasc Surg Date: 2019-10-31 Impact factor: 5.209