| Literature DB >> 3415688 |
Y Kohama1, S Matsumoto, H Oka, T Teramoto, M Okabe, T Mimura.
Abstract
A novel inhibitor of angiotensin-converting enzyme (ACE) has been discovered and isolated in a pure form from acid extract of tuna muscle by successive column chromatographies and HPLC. The final preparation showed IC50 values of 1 microM and 2 microM for ACEs from bovine and rabbit lungs, respectively. The amino acid sequence of the inhibitor has been established as Pro-Thr-His-Ile-Lys-Trp-Gly-Asp by the Edman procedure and carboxypeptidase digestion.Entities:
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Year: 1988 PMID： 3415688 DOI： 10.1016/s0006-291x(88)81089-1
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575