Literature DB >> 3415435

Preliminary evidence on metabolic rehabilitation of cancer patients.

V M Dilman1, L M Berstein, T P Yevtushenko, Y V Tsyrlina, M N Ostroumova, I G Kovalenko, N N Simonov.   

Abstract

Pathways of metabolic rehabilitation of cancer patients are discussed. The effectiveness of a long-term carbohydrate, fat and cholesterol restricted diet and hypolipidemic and antidiabetic medication for breast, gastric and colorectal cancers was demonstrated for the first time. The results of gastro-intestinal cancer treatment were especially encouraging. Metabolic rehabilitation chiefly resulted in a lower frequency of metastatic spread. Also, its effect was seen in a rarer primary multiple tumor development. The results make a case for further development of investigations in normalizing fat-carbohydrate metabolism as adjuvant therapy for cancer in postoperative period.

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Mesh:

Year:  1988        PMID: 3415435

Source DB:  PubMed          Journal:  Arch Geschwulstforsch        ISSN: 0003-911X


  13 in total

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Journal:  Cancer J       Date:  2015 Mar-Apr       Impact factor: 3.360

Review 2.  The key role of growth hormone-insulin-IGF-1 signaling in aging and cancer.

Authors:  Vladimir N Anisimov; Andrzej Bartke
Journal:  Crit Rev Oncol Hematol       Date:  2013-02-21       Impact factor: 6.312

Review 3.  Metformin in cancer prevention and therapy.

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Journal:  Ann Transl Med       Date:  2014-06

Review 4.  Do metformin a real anticarcinogen? A critical reappraisal of experimental data.

Authors:  Vladimir N Anisimov
Journal:  Ann Transl Med       Date:  2014-06

5.  Genetic polymorphisms potentially associated with response to metformin in postmenopausal diabetics suffering and not suffering with cancer.

Authors:  Lev M Berstein; Aglaya G Iyevleva; Dmitry Vasilyev; Tatyana E Poroshina; Evgeny N Imyanitov
Journal:  Cell Cycle       Date:  2013-10-21       Impact factor: 4.534

Review 6.  Metformin: do we finally have an anti-aging drug?

Authors:  Vladimir N Anisimov
Journal:  Cell Cycle       Date:  2013-10-24       Impact factor: 4.534

Review 7.  Metformin for aging and cancer prevention.

Authors:  Vladimir N Anisimov
Journal:  Aging (Albany NY)       Date:  2010-11       Impact factor: 5.682

8.  If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice.

Authors:  Vladimir N Anisimov; Lev M Berstein; Irina G Popovich; Mark A Zabezhinski; Peter A Egormin; Tatiana S Piskunova; Anna V Semenchenko; Margarita L Tyndyk; Maria N Yurova; Irina G Kovalenko; Tatiana E Poroshina
Journal:  Aging (Albany NY)       Date:  2011-02       Impact factor: 5.682

Review 9.  Understanding the benefit of metformin use in cancer treatment.

Authors:  Ryan J O Dowling; Pamela J Goodwin; Vuk Stambolic
Journal:  BMC Med       Date:  2011-04-06       Impact factor: 8.775

Review 10.  Metformin in obesity, cancer and aging: addressing controversies.

Authors:  Lev M Berstein
Journal:  Aging (Albany NY)       Date:  2012-05       Impact factor: 5.682

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