Literature DB >> 34152531

Pre-Exposure Prophylaxis (PrEP) Dissemination: Adapting Diffusion Theory to Examine PrEP Adoption.

Ashley Schuyler1, Zainab Alidina2, M Margaret Dolcini2, Gary Harper3, J Dennis Fortenberry4, Ryan Singh5, Omar Jamil3, Lance Pollack6, Joseph Catania2.   

Abstract

PrEP adoption among African-American men-who-have-sex-with-men (AAMSM) remains low. We applied Diffusion-of-Innovations (DOI) theory to understand PrEP adoption processes among young HIV-negative/status unknown AAMSM (AAYMSM; N = 181; 17-24 years). Quantitative and qualitative analyses were used to examine predictors of PrEP diffusion stages. Most AAYMSM were in the persuasion stage (PrEP-aware, hadn't adopted; 72.4%). Our results suggest that model antecedents are DOI stage-specific. PrEP awareness (knowledge stage) was associated with lower levels of social stigma (p < .03) and greater health literacy (p < .05), while sexual risk (p < .03) and education (p < .03) predicted PrEP adoption (12.2%). PrEP efficacy and side effects were primary innovation characteristics influencing adoption receptivity in the persuasion stage. Interventions to improve PrEP diffusion should be tailored to stage-specific antecedents depending on how a community is stratified across the DOI stages.
© 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  African American; Diffusion; HIV/AIDS; MSM; Social stigma

Mesh:

Substances:

Year:  2021        PMID: 34152531     DOI: 10.1007/s10461-021-03345-2

Source DB:  PubMed          Journal:  AIDS Behav        ISSN: 1090-7165


  51 in total

Review 1.  Evolution of diffusion and dissemination theory.

Authors:  James W Dearing
Journal:  J Public Health Manag Pract       Date:  2008 Mar-Apr

2.  Reframing the dissemination challenge: a marketing and distribution perspective.

Authors:  Matthew W Kreuter; Jay M Bernhardt
Journal:  Am J Public Health       Date:  2009-10-15       Impact factor: 9.308

3.  Challenges in Translating PrEP Interest Into Uptake in an Observational Study of Young Black MSM.

Authors:  Charlotte-Paige Rolle; Eli S Rosenberg; Aaron J Siegler; Travis H Sanchez; Nicole Luisi; Kevin Weiss; Scott Cutro; Carlos Del Rio; Patrick S Sullivan; Colleen F Kelley
Journal:  J Acquir Immune Defic Syndr       Date:  2017-11-01       Impact factor: 3.731

4.  Estimates of adults with indications for HIV pre-exposure prophylaxis by jurisdiction, transmission risk group, and race/ethnicity, United States, 2015.

Authors:  Dawn K Smith; Michelle Van Handel; Jeremy Grey
Journal:  Ann Epidemiol       Date:  2018-05-18       Impact factor: 3.797

5.  Facebook network structure and awareness of preexposure prophylaxis among young men who have sex with men.

Authors:  Aditya S Khanna; Phil Schumm; John A Schneider
Journal:  Ann Epidemiol       Date:  2016-11-29       Impact factor: 3.797

6.  Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: an observational cohort study.

Authors:  Jean-Michel Molina; Isabelle Charreau; Bruno Spire; Laurent Cotte; Julie Chas; Catherine Capitant; Cecile Tremblay; Daniela Rojas-Castro; Eric Cua; Armelle Pasquet; Camille Bernaud; Claire Pintado; Constance Delaugerre; Luis Sagaon-Teyssier; Soizic Le Mestre; Christian Chidiac; Gilles Pialoux; Diane Ponscarme; Julien Fonsart; David Thompson; Mark A Wainberg; Veronique Doré; Laurence Meyer
Journal:  Lancet HIV       Date:  2017-07-23       Impact factor: 12.767

7.  Ongoing Disparities in Prediagnosis Preexposure Prophylaxis Use Among Persons Recently Diagnosed With HIV in New York City, 2015-2017.

Authors:  Kavita Misra; Jamie S Huang; Chi-Chi N Udeagu
Journal:  Am J Public Health       Date:  2019-07-18       Impact factor: 9.308

8.  Racial/ethnic and HIV risk category disparities in preexposure prophylaxis discontinuation among patients in publicly funded primary care clinics.

Authors:  Hyman M Scott; Matthew Spinelli; Eric Vittinghoff; Alicia Morehead-Gee; Anne Hirozawa; Catherine James; Hali Hammer; Albert Liu; Monica Gandhi; Susan Buchbinder
Journal:  AIDS       Date:  2019-11-15       Impact factor: 4.177

9.  Minimal Awareness and Stalled Uptake of Pre-Exposure Prophylaxis (PrEP) Among at Risk, HIV-Negative, Black Men Who Have Sex with Men.

Authors:  Lisa A Eaton; Daniel D Driffin; Jose Bauermeister; Harlan Smith; Christopher Conway-Washington
Journal:  AIDS Patient Care STDS       Date:  2015-06-17       Impact factor: 5.078

10.  Preexposure Prophylaxis Awareness and Use in a Population-Based Sample of Young Black Men Who Have Sex With Men.

Authors:  Aditya S Khanna; Stuart Michaels; Britt Skaathun; Ethan Morgan; Keith Green; Lindsay Young; John A Schneider
Journal:  JAMA Intern Med       Date:  2016-01       Impact factor: 21.873

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