Literature DB >> 3415233

Isolation and characterization of trichothecin from corn cultures of Fusarium graminearum MRC 1125.

S Combrinck1, W C Gelderblom, H S Spies, B V Burger, P G Thiel, W F Marasas.   

Abstract

Trichothecin was isolated and purified from corn cultures of a toxic strain of Fusarium graminearum. This strain, designated MRC 1125, was obtained from corn in southern Africa. The brine shrimp toxicity assay was used throughout the isolation procedure to monitor the toxicity of the fractions. The compound was characterized by detailed 1H (500-MHz) and 13C (125-MHz) nuclear magnetic resonance spectroscopy and mass spectrometry. This is the first report of the production of trichothecin by a Fusarium species.

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Year:  1988        PMID： 3415233      PMCID： PMC202731          DOI： 10.1128/aem.54.7.1700-1702.1988

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  6 in total

1.  The isolation and chemical properties of trichothecin, an antifungal substance from Trichothecium roseum Link.

Authors:  G G Freeman; R I Morrison
Journal:  Biochem J       Date:  1949       Impact factor: 3.857

2.  Occurrence of trichothecin in wheat.

Authors:  K Ishii; J Kobayashi; Y Ueno; M Ichinoe
Journal:  Appl Environ Microbiol       Date:  1986-08       Impact factor: 4.792

3.  Natural occurrence of Fusarium toxins in feedstuff.

Authors:  C J Mirocha; S V Pathre; B Schauerhamer; C M Christensen
Journal:  Appl Environ Microbiol       Date:  1976-10       Impact factor: 4.792

4.  Biological and chemical detection of trichothecene mycotoxins of Fusarium species.

Authors:  Y Ueno; N Sato; K Ishii; K Sakai; H Tsunoda
Journal:  Appl Microbiol       Date:  1973-04

5.  Improved methodology for the simultaneous detection of the trichothecene mycotoxins deoxynivalenol and nivalenol in cereals.

Authors:  T Tanaka; A Hasegawa; Y Matsuki; K Ishii; Y Ueno
Journal:  Food Addit Contam       Date:  1985 Apr-Jun

6.  Comparative yields of T-2 toxin and related trichothecenes from five toxicologically important strains of Fusarium sporotrichioides.

Authors:  W F Marasas; B Yagen; E Sydenham; S Combrinck; P G Thiel
Journal:  Appl Environ Microbiol       Date:  1987-04       Impact factor: 4.792
  6 in total
  3 in total

1.  Reexamination ofFusarium graminearum NRRL-13820and NRRL-13852 reported as type A trichothecene producers.

Authors:  A Logrieco; R F Vesonder; A Bottalico
Journal:  Mycotoxin Res       Date:  1993-03       Impact factor: 3.833

2.  Isolation, identification and toxicological characterization of TSS 1, a new mycotoxin of the rosenane class.

Authors:  M Schäfer; J Hengstler; S Löffler; P Flesch
Journal:  Mycotoxin Res       Date:  1990-03       Impact factor: 3.833

Review 3.  Biological detoxification of the mycotoxin deoxynivalenol and its use in genetically engineered crops and feed additives.

Authors:  Petr Karlovsky
Journal:  Appl Microbiol Biotechnol       Date:  2011-06-21       Impact factor: 4.813
  3 in total

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