Literature DB >> 3414915

Absorption of buccal morphine. A comparison with slow-release morphine sulphate.

A P Fisher1, C Fung, M Hanna.   

Abstract

The absorption of buccal morphine was compared with that of slow-release morphine sulphate in human volunteers. Morphine concentration was assayed by high pressure liquid chromatography in serum samples obtained at intervals up to 8 hours after administration of morphine 20 mg. Similar mean maximum concentrations were obtained by either route, but the mean time to maximum concentration was longer after buccal than after enteral administration.

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Year:  1988        PMID: 3414915     DOI: 10.1111/j.1365-2044.1988.tb06684.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  2 in total

1.  An investigation of premedication with morphine given by the buccal or intramuscular route.

Authors:  K H Simpson; I C Tring; F R Ellis
Journal:  Br J Clin Pharmacol       Date:  1989-03       Impact factor: 4.335

2.  Use of buccal morphine in the management of pain in children with life-limiting conditions: Results of a laboratory study.

Authors:  Renée McCulloch; Mohammed Sattar; Ellen M Henderson; Majella E Lane; Myra Bluebond-Langner
Journal:  Palliat Med       Date:  2017-06-20       Impact factor: 4.762

  2 in total

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