Irene Lafuente-Ibáñez de Mendoza1, Amaia Cayero-Garay1, Guillermo Quindós-Andrés2, José Manuel Aguirre-Urizar3. 1. Department of Stomatology II, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940, Leioa, Vizcaya, Spain. 2. Department of Immunology, Microbiology and Parasitology, University of the Basque Country (UPV/EHU), Leioa, Vizcaya, Spain. 3. Department of Stomatology II, University of the Basque Country (UPV/EHU), Barrio Sarriena s/n, 48940, Leioa, Vizcaya, Spain. Josemanuel.aguirre@ehu.eus.
Abstract
BACKGROUND: Candida is a heterogeneous fungal genus. Subgingival sulcus is a refuge for Candida, which has already been related to the pathogenic inflammation of periodontitis. This work aims to review the presence of Candida in the sulcular fluid surrounding dental implants and discuss its potential role in peri-implantitis. RESULTS: A bibliographical research was performed in PubMed, Scopus and Web of Science databases, with the keywords candida, peri-implantitis, periimplantitis, "dental implant" and implant. Newcastle-Ottawa Scale was used to assess the methodological quality of the included studies. At the end, nine observational studies were included, which analysed 400 dental implants with PI and 337 without peri-implantitis. Presence of Candida was assessed by traditional microbiological culture in blood agar or/and CHROMagar, though identification was also detected by quantitative real-time PCR, random amplified polymorphic DNA or ATB ID 32C. Dentate individuals and implants with peri-implantitis (range, 3-76.7%) had a bigger presence of Candida. C. albicans was the most isolated species, followed by Candida parapsilosis, Candida tropicalis, and Candida dubliniensis. CONCLUSION: Candida is part of the microbiological profile of the peri-implant sulcular fluid. More studies are needed to compare the link between Candida and other microorganisms and to discover the true role of these fungi in peri-implantitis.
BACKGROUND:Candida is a heterogeneous fungal genus. Subgingival sulcus is a refuge for Candida, which has already been related to the pathogenic inflammation of periodontitis. This work aims to review the presence of Candida in the sulcular fluid surrounding dental implants and discuss its potential role in peri-implantitis. RESULTS: A bibliographical research was performed in PubMed, Scopus and Web of Science databases, with the keywords candida, peri-implantitis, periimplantitis, "dental implant" and implant. Newcastle-Ottawa Scale was used to assess the methodological quality of the included studies. At the end, nine observational studies were included, which analysed 400 dental implants with PI and 337 without peri-implantitis. Presence of Candida was assessed by traditional microbiological culture in blood agar or/and CHROMagar, though identification was also detected by quantitative real-time PCR, random amplified polymorphic DNA or ATB ID 32C. Dentate individuals and implants with peri-implantitis (range, 3-76.7%) had a bigger presence of Candida. C. albicans was the most isolated species, followed by Candida parapsilosis, Candida tropicalis, and Candida dubliniensis. CONCLUSION:Candida is part of the microbiological profile of the peri-implant sulcular fluid. More studies are needed to compare the link between Candida and other microorganisms and to discover the true role of these fungi in peri-implantitis.
Authors: Ioannis K Karoussis; Giovanni E Salvi; Lisa J A Heitz-Mayfield; Urs Brägger; Christoph H F Hämmerle; Niklaus P Lang Journal: Clin Oral Implants Res Date: 2003-06 Impact factor: 5.977
Authors: Matteo Albertini; Lorena López-Cerero; Manuel G O'Sullivan; Carlos F Chereguini; Sofia Ballesta; Vicente Ríos; Mariano Herrero-Climent; Pedro Bullón Journal: Clin Oral Implants Res Date: 2014-04-10 Impact factor: 5.977
Authors: João G S Souza; Raphael C Costa; Aline A Sampaio; Victória L Abdo; Bruna E Nagay; Nidia Castro; Belén Retamal-Valdes; Jamil A Shibli; Magda Feres; Valentim A R Barão; Martinna Bertolini Journal: iScience Date: 2022-03-01