Literature DB >> 34122767

Role of Platelet Rich Plasma in Chronic Plantar Fasciitis: A Prospective Study.

R B Kalia1, Vivek Singh1, Nilotpal Chowdhury2, Ashish Jain3, Sanny Kumar Singh1, Lakshmana Das1.   

Abstract

INTRODUCTION: Autologous platelet rich plasma (PRP) local injection has been recently proposed as a treatment of plantar fasciitis. The autologous PRP does not have much side effects compared to steroid injections. So far PRP injections have shown promising results in various studies. This study assessed the efficacy of a single local injection of PRP in chronic unilateral plantar fasciitis through a prospective case series.
METHODOLOGY: A hospital-based prospective case series of 30 unilateral plantar fasciitis patients with symptom duration of 6 months or more were included in the study. All patients included in the study were assessed clinically and by visual analogue score for heel pain, AHS component of AOFAS and FADI scores before injection and at 6 and 12 week follow-up. USG measurement of plantar fascia thickness was done at pre-injection and at 12 weeks follow-up. All patients were observed for 12 weeks.
RESULTS: The mean age was 39 years (range 20-55 years). The pre-injection VAS score for heel pain was 6.5 ± 1.1 which improved to 2.7 ± 0.5 and 1.8 ± 0.8 at 6 and 12 week respectively and difference was significant (p < 0.001). The baseline FADI and AHS component of AOFAS scores were 53.1 ± 9.0 and 72.2 ± 5.7 which improved to 65.5 ± 5.3 and 76.1 ± 4.5 at 6 weeks and, 77.9 ± 4.4 and 85.7 ± 4.6 at 12 weeks respectively which was significant (p < 0.001). The baseline mean plantar fascia thickness was 4.9 ± 0.3 mm which was significantly (p < 0.001) reduced to 3.9 ± 0.3 mm at 12 weeks post PRP injection. All pairwise comparisons by the post-hoc Wilcoxon signed rank test with p-value adjustment were also significant.
CONCLUSION: The short-term results of single dose PRP injections shows clinical and statistically significant improvements in VAS for heel pain, functional outcome scores and plantar fascia thickness measured by USG. This study concludes that local PRP injection is a viable management option for chronic plantar fasciitis. © Indian Orthopaedics Association 2020.

Entities:  

Keywords:  Plantar fascia thickness; Plantar fasciitis; Platelet rich plasma; USG; Ultrasound

Year:  2020        PMID: 34122767      PMCID: PMC8149543          DOI: 10.1007/s43465-020-00261-w

Source DB:  PubMed          Journal:  Indian J Orthop        ISSN: 0019-5413            Impact factor:   1.251


  37 in total

1.  PAINFUL HEEL: REPORT OF 323 PATIENTS WITH 364 PAINFUL HEELS.

Authors:  P W LAPIDUS; F P GUIDOTTI
Journal:  Clin Orthop Relat Res       Date:  1965 Mar-Apr       Impact factor: 4.176

2.  Complications of plantar fascia rupture associated with corticosteroid injection.

Authors:  J I Acevedo; J L Beskin
Journal:  Foot Ankle Int       Date:  1998-02       Impact factor: 2.827

3.  Ultrasound guided injection of dexamethasone versus placebo for treatment of plantar fasciitis: protocol for a randomised controlled trial.

Authors:  Andrew M McMillan; Karl B Landorf; Mark F Gilheany; Adam R Bird; Adam D Morrow; Hylton B Menz
Journal:  J Foot Ankle Res       Date:  2010-07-16       Impact factor: 2.303

4.  Risk factors for Plantar fasciitis: a matched case-control study.

Authors:  Daniel L Riddle; Matthew Pulisic; Peter Pidcoe; Robert E Johnson
Journal:  J Bone Joint Surg Am       Date:  2003-05       Impact factor: 5.284

5.  Investigation of the freely available easy-to-use software 'EZR' for medical statistics.

Authors:  Y Kanda
Journal:  Bone Marrow Transplant       Date:  2012-12-03       Impact factor: 5.483

Review 6.  The roles of growth factors in tendon and ligament healing.

Authors:  Timothy Molloy; Yao Wang; George Murrell
Journal:  Sports Med       Date:  2003       Impact factor: 11.136

7.  Intralesional autologous blood injection compared to corticosteroid injection for treatment of chronic plantar fasciitis. A prospective, randomized, controlled trial.

Authors:  Tze Gin Lee; Tunku Sara Ahmad
Journal:  Foot Ankle Int       Date:  2007-09       Impact factor: 2.827

Review 8.  Plantar fasciopathy: revisiting the risk factors.

Authors:  P Beeson
Journal:  Foot Ankle Surg       Date:  2014-03-22       Impact factor: 2.705

9.  Foreign-body reaction and the course of osteolysis after polyglycolide implants for fracture fixation: experimental study in sheep.

Authors:  A Weiler; H J Helling; U Kirch; T K Zirbes; K E Rehm
Journal:  J Bone Joint Surg Br       Date:  1996-05

10.  Comparing the Role of Different Treatment Modalities for Plantar Fasciitis: A Double Blind Randomized Controlled Trial.

Authors:  Ravi Gupta; Anubhav Malhotra; Gladson David Masih; Tanu Khanna; Harsimranjit Kaur; Parmanand Gupta; Shweta Kashyap
Journal:  Indian J Orthop       Date:  2020-01-20       Impact factor: 1.251

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