Andrea Giustina1. 1. Institute of Endocrine and Metabolic Sciences, San Raffaele, Vita-Salute University and IRCCS Hospital, Milano, Italy. giustina.andrea@hsr.it.
Abstract
BACKGROUND: In 2017, the International Pituitary Pathology Club proposed to rename pituitary adenoma as pituitary neuroendocrine tumors (PitNETs) but since no consensus on this new terminology was obtained the Pituitary Society decided to host on this topic an international multidisciplinary virtual workshop, Pituitary Neoplasm Nomenclature (PANOMEN), to which several Societies participated with the designation of their representatives in the expert panel. Main conclusion of the meeting was that there was not yet a case for adopting the PitNET nomenclature and main recommendation was that the term adenoma is retained. AIM: Aim of this Editorial is to comment the outcome of the recently published document of the meeting. CONCLUSIONS: Ideally, only the combination of pathological, neuroradiological, and clinical data can define the degree of agressiveness/invasion of a pituitary adenoma and effectively guide treament. This may be classically obtained only with a close multisciplinary collaboration into a PTCOE. It is proposed that improved definition of "invasive" and "aggressive" neoplasms may represent the most clinically effective development in the clinico-neuroradiological-pathological denomination and classification of pituitary adenomas.
BACKGROUND: In 2017, the International Pituitary Pathology Club proposed to rename pituitary adenoma as pituitary neuroendocrine tumors (PitNETs) but since no consensus on this new terminology was obtained the Pituitary Society decided to host on this topic an international multidisciplinary virtual workshop, Pituitary Neoplasm Nomenclature (PANOMEN), to which several Societies participated with the designation of their representatives in the expert panel. Main conclusion of the meeting was that there was not yet a case for adopting the PitNET nomenclature and main recommendation was that the term adenoma is retained. AIM: Aim of this Editorial is to comment the outcome of the recently published document of the meeting. CONCLUSIONS: Ideally, only the combination of pathological, neuroradiological, and clinical data can define the degree of agressiveness/invasion of a pituitary adenoma and effectively guide treament. This may be classically obtained only with a close multisciplinary collaboration into a PTCOE. It is proposed that improved definition of "invasive" and "aggressive" neoplasms may represent the most clinically effective development in the clinico-neuroradiological-pathological denomination and classification of pituitary adenomas.
Authors: Pietro Mortini; Gianluca Nocera; Francesca Roncelli; Marco Losa; Anna Maria Formenti; Andrea Giustina Journal: Rev Endocr Metab Disord Date: 2020-12 Impact factor: 6.514
Authors: Andrea Giustina; Ariel Barkan; Albert Beckers; Nienke Biermasz; Beverly M K Biller; Cesar Boguszewski; Marek Bolanowski; Vivien Bonert; Marcello D Bronstein; Felipe F Casanueva; David Clemmons; Annamaria Colao; Diego Ferone; Maria Fleseriu; Stefano Frara; Monica R Gadelha; Ezio Ghigo; Mark Gurnell; Anthony P Heaney; Ken Ho; Adriana Ioachimescu; Laurence Katznelson; Fahrettin Kelestimur; John Kopchick; Michal Krsek; Steven Lamberts; Marco Losa; Anton Luger; Pietro Maffei; Monica Marazuela; Gherardo Mazziotti; Moises Mercado; Pietro Mortini; Sebastian Neggers; Alberto M Pereira; Stephan Petersenn; Manel Puig-Domingo; Roberto Salvatori; Ilan Shimon; Christian Strasburger; Stylianos Tsagarakis; A J van der Lely; John Wass; Maria Chiara Zatelli; Shlomo Melmed Journal: J Clin Endocrinol Metab Date: 2020-04-01 Impact factor: 5.958
Authors: A Giustina; M D Bronstein; F F Casanueva; P Chanson; E Ghigo; K K Y Ho; A Klibanski; S Lamberts; P Trainer; S Melmed Journal: Pituitary Date: 2011-06 Impact factor: 4.107
Authors: Stefano Frara; Gemma Rodriguez-Carnero; Ana M Formenti; Miguel A Martinez-Olmos; Andrea Giustina; Felipe F Casanueva Journal: Endocrinol Metab Clin North Am Date: 2020-07-15 Impact factor: 4.741
Authors: Andrea Giustina; Garni Barkhoudarian; Albert Beckers; Anat Ben-Shlomo; Nienke Biermasz; Beverly Biller; Cesar Boguszewski; Marek Bolanowski; Jens Bollerslev; Vivien Bonert; Marcello D Bronstein; Michael Buchfelder; Felipe Casanueva; Philippe Chanson; David Clemmons; Maria Fleseriu; Anna Maria Formenti; Pamela Freda; Monica Gadelha; Eliza Geer; Mark Gurnell; Anthony P Heaney; Ken K Y Ho; Adriana G Ioachimescu; Steven Lamberts; Edward Laws; Marco Losa; Pietro Maffei; Adam Mamelak; Moises Mercado; Mark Molitch; Pietro Mortini; Alberto M Pereira; Stephan Petersenn; Kalmon Post; Manuel Puig-Domingo; Roberto Salvatori; Susan L Samson; Ilan Shimon; Christian Strasburger; Brooke Swearingen; Peter Trainer; Mary L Vance; John Wass; Margaret E Wierman; Kevin C J Yuen; Maria Chiara Zatelli; Shlomo Melmed Journal: Rev Endocr Metab Disord Date: 2020-09-10 Impact factor: 6.514
Authors: Andrea Giustina; Marcello D Bronstein; Philippe Chanson; Stephan Petersenn; Felipe F Casanueva; Caroline Sert; Aude Houchard; Shlomo Melmed Journal: Pituitary Date: 2019-10 Impact factor: 4.107
Authors: Shlomo Melmed; Marcello D Bronstein; Philippe Chanson; Anne Klibanski; Felipe F Casanueva; John A H Wass; Christian J Strasburger; Anton Luger; David R Clemmons; Andrea Giustina Journal: Nat Rev Endocrinol Date: 2018-09 Impact factor: 43.330
Authors: Ken Ho; Maria Fleseriu; Ursula Kaiser; Roberto Salvatori; Thierry Brue; M Beatriz Lopes; Pamela Kunz; Mark Molitch; Sally A Camper; Mônica Gadelha; Luis V Syro; Edward Laws; Martin Reincke; Hiroshi Nishioka; Ashley Grossman; Ariel Barkan; Felipe Casanueva; John Wass; Adam Mamelak; Laurence Katznelson; Aart J van der Lely; Sally Radovick; Martin Bidlingmaier; Margaret Boguszewski; Jens Bollerslev; Andrew R Hoffman; Nelson Oyesiku; Gerald Raverot; Anat Ben-Shlomo; Rob Fowkes; Ilan Shimon; Hidenori Fukuoka; Alberto M Pereira; Yona Greenman; Anthony P Heaney; Mark Gurnell; Gudmundur Johannsson; Robert Y Osamura; Michael Buchfelder; Maria Chiara Zatelli; Marta Korbonits; Philippe Chanson; Nienke Biermasz; David R Clemmons; Niki Karavitaki; Marcello D Bronstein; Peter Trainer; Shlomo Melmed Journal: J Endocr Soc Date: 2021-02-09