Literature DB >> 341085

Genetically determined differences in concentrations of isoaccepting tRNAs in Escherichia coli.

J Thomale, G Nass.   

Abstract

Two examples of genetically determined altered concentrations of isoaccepting tRNAs are presented. The concentrations of isoaccepting tRNAsThr are selectively changed by a mutation causing a fourfold overproduction of the cognate aminoacyl-tRNA-synthetase, the threonyl-tRNA synthetase, whereas the distribution of isoaccepting tRNAs of four control tRNA-species in these E. coli mutants was not affected by that mutation. Secondly evidence is presented for a correlation between mutations in structural genes of aminoacid biosynthetic enzymes and alterations in concentrations of cognate isoaccepting tRNAs in two different E. coli strains, auxotrophic for threonine, isoleucine/valine and leucine, and arginine respectively.

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Year:  1977        PMID： 341085      PMCID： PMC343243          DOI： 10.1093/nar/4.12.4313

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  29 in total

1.  Mutations affecting tRNATrp and its charging and their effect on regulation of transcription termination at the attenuator of the tryptophan operon.

Authors:  C Yanofsky
Journal:  J Mol Biol       Date:  1977-07-15       Impact factor: 5.469

2.  Alteration of structure of level of threonyl-tRNA-synthetase in Borrelidin resistant mutants of E. coli.

Authors:  G Nass; J Thomale
Journal:  FEBS Lett       Date:  1974-02-15       Impact factor: 4.124

3.  S-Adenosylmethionine and tetrahydrofolate-dependent methylation of tRNA in Bacillus subtilis. Incomplete methylations caused by trimethoprim, pactamycin, or chloramphenicol.

Authors:  H H Arnold; W Schmidt; R Raettig; L Sandig; H Domdey; H Kersten
Journal:  Arch Biochem Biophys       Date:  1976-09       Impact factor: 4.013

4.  A general method for the separation of isoaccepting transfer ribonucleic acids: purification of five leucine transfer ribonucleic acids from Escherichia coli.

Authors:  D W Holladay; R L Pearson; A D Kelmers
Journal:  Biochim Biophys Acta       Date:  1971-07-29

5.  Threonyl-transfer ribonucleic acid synthetase and the regulation of the threonine operon in Escherichia coli.

Authors:  E J Johnson; G N Cohen; I Saint-Girons
Journal:  J Bacteriol       Date:  1977-01       Impact factor: 3.490

6.  Detection of messenger RNA from the isoleucine--valine operons of Salmonella typhimurium by heterologous DNA-RNA hybridization: involvement of transfer RNA in transcriptional repression.

Authors:  G Childs; F Sonnenberg; M Freundlich
Journal:  Mol Gen Genet       Date:  1977-03-07

7.  Modification-deficient transfer ribonucleic acids from relaxed control Escherichia coli: structures of the major undermodified phenylalanine and leucine transfer RNAs produced during leucine starvation.

Authors:  G R Kitchingman; M J Fournier
Journal:  Biochemistry       Date:  1977-05-17       Impact factor: 3.162

8.  Derepressed levels of the isoleucine-valine and leucine enzymes in his T 1504, a strain of Salmonella typhimurium with altered leucine transfer ribonucleic acid.

Authors:  A A Rizzino; R S Bresalier; M Freundlich
Journal:  J Bacteriol       Date:  1974-02       Impact factor: 3.490

9.  Pleiotropy of hisT mutants blocked in pseudouridine synthesis in tRNA: leucine and isoleucine-valine operons.

Authors:  R Cortese; R Landsberg; R A Haar; H E Umbarger; B N Ames
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

10.  Threonyl-transfer ribonucleic acid synthetase from Escherichia coli: subunit structure and genetic analysis of the structural gene by means of a mutated enzyme and of a specialized transducing lambda bacteriophage.

Authors:  H Hennecke; A Böck; J Thomale; G Nass
Journal:  J Bacteriol       Date:  1977-09       Impact factor: 3.490
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  2 in total

1.  Genetic analysis of mutations causing borrelidin resistance by overproduction of threonyl-transfer ribonucleic acid synthetase.

Authors:  J Fröhler; A Rechenmacher; J Thomale; G Nass; A Böck
Journal:  J Bacteriol       Date:  1980-09       Impact factor: 3.490

2.  Threonine tRNAs and their genes in Escherichia coli.

Authors:  M M Comer
Journal:  Mol Gen Genet       Date:  1982
  2 in total

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