Literature DB >> 34107541

Evaluation of Clinical Decision Support to Reduce Sedative-Hypnotic Prescribing in Older Adults.

Natasha N Joglekar1, Yatindra Patel2, Michelle S Keller2,3,4.   

Abstract

OBJECTIVE: We sought to characterize the performance of inpatient and outpatient computerized clinical decision support (CDS) alerts aimed at reducing inappropriate benzodiazepine and nonbenzodiazepine sedative medication prescribing in older adults 18 months after implementation.
METHODS: We reviewed the performance of two CDS alerts in the outpatient and inpatient settings in 2019. To examine the alerts' effectiveness, we analyzed metrics including overall alert adherence, provider-level adherence, and reasons for alert trigger and override.
RESULTS: In 2019, we identified a total of 14,534 and 4,834 alerts triggered in the outpatient and inpatient settings, respectively. Providers followed only 1% of outpatient and 3% of inpatient alerts. Most alerts were ignored (68% outpatient and 60% inpatient), while providers selected to override the remaining alerts. In each setting, the top 2% of clinicians were responsible for approximately 25% of all ignored or overridden alerts. However, a small proportion of clinicians (2% outpatient and 4% inpatient) followed the alert at least half of the time and accounted for a disproportionally large fraction of the total followed alerts. Our analysis of the free-text comments revealed that many alerts were to continue outpatient prescriptions or for situational anxiety.
CONCLUSION: Our findings highlight the importance of evaluation of CDS performance after implementation. We found large variation in response to the inpatient and outpatient alerts, both with respect to follow and ignore rates. Reevaluating the alert design by providing decision support by indication may be more helpful and may reduce alert fatigue. Thieme. All rights reserved.

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Year:  2021        PMID: 34107541      PMCID: PMC8189759          DOI: 10.1055/s-0041-1730030

Source DB:  PubMed          Journal:  Appl Clin Inform        ISSN: 1869-0327            Impact factor:   2.762


  30 in total

1.  Types of unintended consequences related to computerized provider order entry.

Authors:  Emily M Campbell; Dean F Sittig; Joan S Ash; Kenneth P Guappone; Richard H Dykstra
Journal:  J Am Med Inform Assoc       Date:  2006-06-23       Impact factor: 4.497

Review 2.  Use of computer decision support interventions to improve medication prescribing in older adults: a systematic review.

Authors:  Lindsey Yourman; John Concato; Joseph V Agostini
Journal:  Am J Geriatr Pharmacother       Date:  2008-06

3.  Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies.

Authors:  J Lazarou; B H Pomeranz; P N Corey
Journal:  JAMA       Date:  1998-04-15       Impact factor: 56.272

4.  Opioid prescribing decreases after learning of a patient's fatal overdose.

Authors:  Jason N Doctor; Andy Nguyen; Roneet Lev; Jonathan Lucas; Tara Knight; Henu Zhao; Michael Menchine
Journal:  Science       Date:  2018-08-10       Impact factor: 47.728

5.  Physician Prescribing Patterns and Risk of Future Long-Term Opioid Use Among Patients With Rheumatoid Arthritis: A Prospective Observational Cohort Study.

Authors:  Yvonne C Lee; Bing Lu; Hongshu Guan; Jeffrey D Greenberg; Joel Kremer; Daniel H Solomon
Journal:  Arthritis Rheumatol       Date:  2020-07       Impact factor: 10.995

6.  Effects of Behavioral Interventions on Inappropriate Antibiotic Prescribing in Primary Care 12 Months After Stopping Interventions.

Authors:  Jeffrey A Linder; Daniella Meeker; Craig R Fox; Mark W Friedberg; Stephen D Persell; Noah J Goldstein; Jason N Doctor
Journal:  JAMA       Date:  2017-10-10       Impact factor: 56.272

7.  Clinician Perceptions of Timing and Presentation of Drug-Drug Interaction Alerts.

Authors:  Kate E Humphrey; Maria Mirica; Shobha Phansalkar; Al Ozonoff; Marvin B Harper
Journal:  Appl Clin Inform       Date:  2020-07-22       Impact factor: 2.342

8.  Relationship between medication errors and adverse drug events.

Authors:  D W Bates; D L Boyle; M B Vander Vliet; J Schneider; L Leape
Journal:  J Gen Intern Med       Date:  1995-04       Impact factor: 5.128

Review 9.  Guidelines for the rational use of benzodiazepines. When and what to use.

Authors:  H Ashton
Journal:  Drugs       Date:  1994-07       Impact factor: 9.546

Review 10.  Challenges of the pharmacological management of benzodiazepine withdrawal, dependence, and discontinuation.

Authors:  Dimy Fluyau; Neelambika Revadigar; Brittany E Manobianco
Journal:  Ther Adv Psychopharmacol       Date:  2018-02-09
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  3 in total

1.  Low Efficacy of Medication Shortage Clinical Decision Support Alerts.

Authors:  Nicole M Benson; Caryn Belisle; David W Bates; Hojjat Salmasian
Journal:  Appl Clin Inform       Date:  2021-12-01       Impact factor: 2.342

Review 2.  Modulators Influencing Medication Alert Acceptance: An Explorative Review.

Authors:  Janina A Bittmann; Walter E Haefeli; Hanna M Seidling
Journal:  Appl Clin Inform       Date:  2022-08-18       Impact factor: 2.762

3.  A Qualitative Description of Clinician Free-Text Rationales Entered within Accountable Justification Interventions.

Authors:  Tiffany Brown; Brittany Zelch; Ji Young Lee; Jason N Doctor; Jeffrey A Linder; Mark D Sullivan; Noah J Goldstein; Theresa A Rowe; Daniella Meeker; Tara Knight; Mark W Friedberg; Stephen D Persell
Journal:  Appl Clin Inform       Date:  2022-09-07       Impact factor: 2.762

  3 in total

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