Charles L Bowden1, Richard Priesmeyer1, Mauricio Tohen1, Vivek Singh1, Joseph R Calabrese1, Terry Ketter1, Andrew Nierenberg1, Michael E Thase1, Gregg Siegel1, Leslie H Siegel1, Jim Mintz1, Rif S El-Mallakh1, Susan L McElroy1, Melissa Martinez1. 1. Bowden, M.D., Emeritus Professor, Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas. Priesmeyer, PhD., Jurica Professor of Management, Department of Management and Marketing, St Mary's University, San Antonio, Texas. Tohen, M.D., Dr.P.H., M.B.A, University Distinguished Professor and Chairman, Department of Psychiatry and Behavioral Sciences, University of New Mexico Health Sciences Center, Albuquerque, New Mexico. Singh, M.D., Deceased. Calabrese, M.D., Director, Mood Disorders Program, UH Cleveland Medical Center Case Western Reserve University School of Medicine, Cleveland, Ohio. Ketter, M.D, Emeritus Professor, Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California. Nierenberg, M.D., Director, Dauten Family Center for Bipolar Treatment Innovation Massachusetts General Hospital, Harvard Medical School. Thase, M.D., Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania. Gregg Siegel, M.S, Biomedical Development Corporation, San Antonio, Texas. Leslie H. Siegel, M.F.A, Biomedical Development Corporation, San Antonio, Texas. Mintz, PhD., Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas. Mallakh, M.D., Mood Disorders Research Program, Depression Center, Department of Psychiatry and Behavioral Sciences, University of Louisville School of Medicine, Louisville, Kentucky. McElroy, M.D., Professor of Psychiatry and Behavioral Neuroscience, University of Cincinnati, Cincinnati, Ohio. Martinez, M.D., Professor and Mary Avis Weir Chair in Psychiatry, Director, Adult Mood Disorders Program, Co-Director, Mind, Brain, and Behavior, Department of Psychiatry and Behavioral Sciences University of Texas Health Science Center San Antonio, San Antonio, Texas.
Abstract
Objective: Self-management of bipolar disorder (BD) is an important component of treatment. Methods: We developed a patient-centered computational software system based on concepts from nonlinear systems (chaos) theory with mobile access to assist in managing BD known as KIOS. KIOS tracks interacting symptoms to determine theprecise state of a BD patient. Once the patient's state is identified and the trajectory of the patient established, specific advice is generated to help manage the course of the disease. KIOS also provides analytics that can be used by clinicians and researchers to track outcomes and the course of illness. A 12-week field test was completed. Results: In 20 BD subjects, use of KIOS was associated with improvements in primary symptom categories of BD. Usability and generated advice were rated as a median of 6 out of a maximum of 7. Conclusions: The KIOS focus on change illuminates problems in the same way that humans experience them, implying that the future state will be consequent to changes made to impact the current state. Randomized clinical trial is indicated.
Objective: Self-management of bipolar disorder (BD) is an important component of treatment. Methods: We developed a patient-centered computational software system based on concepts from nonlinear systems (chaos) theory with mobile access to assist in managing BD known as KIOS. KIOS tracks interacting symptoms to determine theprecise state of a BD patient. Once the patient's state is identified and the trajectory of the patient established, specific advice is generated to help manage the course of the disease. KIOS also provides analytics that can be used by clinicians and researchers to track outcomes and the course of illness. A 12-week field test was completed. Results: In 20 BD subjects, use of KIOS was associated with improvements in primary symptom categories of BD. Usability and generated advice were rated as a median of 6 out of a maximum of 7. Conclusions: The KIOS focus on change illuminates problems in the same way that humans experience them, implying that the future state will be consequent to changes made to impact the current state. Randomized clinical trial is indicated.
Authors: Peter M Thompson; Jodi M Gonzalez; Vivek Singh; John D Schoolfield; Martin M Katz; Charles L Bowden Journal: Psychiatry Res Date: 2009-12-21 Impact factor: 3.222
Authors: Victoria L Ives-Deliperi; Fleur Howells; Dan J Stein; Ernesta M Meintjes; Neil Horn Journal: J Affect Disord Date: 2013-06-20 Impact factor: 4.839
Authors: Fleur M Howells; H G Laurie Rauch; Victoria L Ives-Deliperi; Neil R Horn; Dan J Stein Journal: Metab Brain Dis Date: 2013-12-07 Impact factor: 3.584
Authors: Judith Proudfoot; Gordon Parker; Matthew Hyett; Vijaya Manicavasagar; Meg Smith; Sue Grdovic; Leah Greenfield Journal: Aust N Z J Psychiatry Date: 2007-11 Impact factor: 5.744
Authors: C L Bowden; V Singh; P Thompson; J M Gonzalez; M M Katz; M Dahl; T J Prihoda; X Chang Journal: Acta Psychiatr Scand Date: 2007-09 Impact factor: 6.392
Authors: Jennifer Nicholas; Judith Proudfoot; Gordon Parker; Inika Gillis; Rowan Burckhardt; Vijaya Manicavasagar; Meg Smith Journal: J Med Internet Res Date: 2010-12-19 Impact factor: 5.428