| Literature DB >> 3409168 |
Abstract
Tetranectin, a recently identified and characterized human plasma protein related to the fibrinolytic system, was significantly reduced in patients with various malignancies. Plasma tetranectin, measured by enzyme-linked immunosorbent assay (ELISA), was a significant discriminator regarding metastatic or nonmetastatic cancer. It had a high predictive specificity (0.93) and sensitivity (0.75) and only misclassified 14% of patients. Tetranectin may be related to the pathogenetically important processes leading to cancer spread and metastasis. In this respect, it may prove to be of discriminative importance clinically.Entities:
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Year: 1988 PMID: 3409168 DOI: 10.1002/1097-0142(19880901)62:5<869::aid-cncr2820620503>3.0.co;2-6
Source DB: PubMed Journal: Cancer ISSN: 0008-543X Impact factor: 6.860