Alexandra Laurent1,2, Alicia Fournier1, Florent Lheureux3, Guillaume Louis4, Saad Nseir5, Gwenaelle Jacq6, Cyril Goulenok7, Grégoire Muller8, Julio Badie9, Bélaïd Bouhemad2, Marjolaine Georges10, Paul-Michel Mertes11, Hamid Merdji12,13, Vincent Castelain14,15, Caroline Abdulmalak16, Olivier Lesieur17, Gaëtan Plantefeve18, Jean-Claude Lacherade19, Jean-Philippe Rigaud20,21, Nicholas Sedillot22, Damien Roux23,24, Nicolas Terzi25, Pascal Beuret26, Antoine Monsel27,28,29, Anne-Laure Poujol27,30,31, Khaldoun Kuteifan32, Thierry Vanderlinden33, Anne Renault34, Bérengère Vivet35, Christophe Vinsonneau36, Saber Davide Barbar37, Gilles Capellier38,39, Jean Dellamonica40, Stephan Ehrmann41,42,43, Thomas Rimmelé44, Julien Bohé45, Pierre Bouju46, Sébastien Gibot47, Bruno Lévy48, Johanna Temime49, Cyrille Pichot50, David Schnell51, Diane Friedman52, Pierre Asfar53, Eddy Lebas54, Philippe Mateu55, Kada Klouche56, Juliette Audibert57, Fiona Ecarnot58, Nicolas Meunier-Beillard59,60, Mélanie Loiseau61, Irène François-Pursell61, Christine Binquet62, Jean-Pierre Quenot63,64,65,66. 1. Laboratoire de Psychologie: Dynamiques Relationnelles et Processus Identitaires (PsyDREPI), Université de Bourgogne Franche-Comté, Dijon, France. 2. Department of Anaesthesiology and Critical Care Medicine, Dijon University Medical Centre, Dijon, France. 3. Laboratoire de Psychologie, Université de Bourgogne Franche-Comté, Besançon, France. 4. Service de Réanimation Polyvalente et USC, Hôpital de Mercy, CHR Metz-Thionville, Thionville, France. 5. Critical Care Center, CHU Lille and Lille University, Lille, France. 6. Medical-Surgical Intensive Care Unit, CH de Versailles, Le Chesnay, France. 7. Medical-Surgical Intensive Care Unit, Ramsay Générale de Santé, Hôpital Privé Jacques Cartier, Massy, France. 8. Service de Médecine Intensive-Réanimation, CHR d'Orléans, Orléans, France. 9. Service de Réanimation Polyvalente-USC, Hôpital Nord Franche-Comté, Trevenans, France. 10. Service de Pneumologie, CHU Dijon, Dijon, France. 11. Department of Anesthesia and Intensive Care, Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, Strasbourg, France. 12. Faculté de Médecine, Université de Strasbourg (UNISTRA), Strasbourg, France. 13. Service de Médecine Intensive-Réanimation, Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, Strasbourg, France. 14. Hôpitaux Universitaires de Strasbourg, Médecine Intensive - Réanimation, Hôpital de Hautepierre, Strasbourg, France. 15. Fédération de Médecine Translationnelle de Strasbourg, Faculté de Médecine, Université de Strasbourg, Strasbourg, France. 16. Service de Médecine Intensive-Réanimation, CH de Chalon sur Saône, Chalon sur Saône, France. 17. Intensive Care Unit, Groupement Hospitalier La Rochelle-Ré-Aunis, La Rochelle, France. 18. Service de Réanimation Polyvalente et USC, Argenteuil, France. 19. Service de Médecine Intensive-Réanimation, CH de La Roche-sur-Yon, Chalon sur Saône, France. 20. Service de Médecine Intensive-Réanimation, CH de Dieppe, Dieppe, France. 21. Espace de Réflexion Éthique de Normandie, Université de Caen, Caen, France. 22. Réanimation Polyvalente, CH de Bourg-en-Bresse, Bourg-en-Bresse, France. 23. Service de Médecine Intensive Réanimation, Assistance Publique - Hôpitaux de Paris, Hôpital Louis Mourier, Colombes, France. 24. Université de Paris, INSERM, UMR 1137 Infection, Antimicrobials, Modelling, Evolution, Paris, France. 25. Service de Réanimation Médicale, CHU de Grenoble, Grenoble, France. 26. Service de Réanimation-Soins Continus du CH de Roanne, Roanne, France. 27. Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care, La Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, Sorbonne University, Paris, France. 28. Sorbonne University, INSERM, UMR-S 959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France. 29. Biotherapy (CIC-BTi) and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Hôpital Pitié-Salpêtrière, AP-HP, Paris, France. 30. Équipe VCR, École de Psychologues Praticiens, Université Catholique de Paris, EA, 7403, Paris, France. 31. Laboratoire APEMAC, Université de Lorraine, EA 4360, Université́ de Lorraine, Metz, France. 32. Service de Réanimation Médicale, CH de Mulhouse, France. 33. Service de Médecine Intensive Réanimation, Groupe des Hôpitaux de L'Institut Catholique de Lille (GHICL), France, Université Catholique de Lille, Lille, France. 34. Service de Réanimation Médicale et Urgences Médicales, CHU de Brest, Brest, France. 35. Service de Réanimation Polyvalente, Groupe Hospitalier Intercommunal de La Haute-Saône, Site de Vesoul, Luxeuil-les-Bains, France. 36. Service de Médecine Intensive Réanimation-Unité de Sevrage Ventilatoire et Réhabilitation, CH de Bethune, Bethune, France. 37. Service des Réanimations, Faculté de Médecine de Montpellier-Nîmes, CHU de Nîmes, France and Université de Montpellier, Nîmes, France. 38. Réanimation Médicale, University Hospital Besançon, Besançon, France. 39. EA3920, University of Burgundy-Franche-Comté, Besançon, France. 40. Medical ICU University Hospital of Nice/UR2CA, Tours, France. 41. Service de Médecine Intensive-Réanimation, Tours, France. 42. CIC INSERM 1415, CRICS-TriggerSep Network, Tours, France. 43. INSERM, Centre d'étude des pathologies respiratoires, Université de Tours, U1100, Tours, France. 44. Anesthesiology and Intensive Care Medicine, Edouard Herriot Hospital, Lyon, France. 45. Service D'anesthésie - Réanimation-Médecine Intensive, CH Lyon-Sud, Hospices Civils de Lyon, Pierre Bénite, Tours, France. 46. Service Réanimation Polyvalente, Groupe Hospitalier Bretagne Sud, Lorient, France. 47. Service de Réanimation Médicale, Hôpital Central, Nancy, France. 48. Service de Réanimation Médicale, Centre Hospitalier Universitaire Nancy Brabois, Nancy-France-Institut du Cœur et des Vaisseaux. Groupe Choc, équipe 2, Inserm U1116. Faculté de Médecine, Nancy-Brabois, France. 49. Service de Réanimation Polyvalente, Lens, France. 50. Unité de Surveillance Continue, CH de Dôle, Dôle, France. 51. Service de Réanimation Polyvalente et USC, CH d'Angoulême, Angoulême, France. 52. Service de Médecine Intensive et Réanimation, Hôpital Raymond Poincaré, Garches, France. 53. Département de Médecine Intensive-Réanimation, CHU Angers, Angers, France. 54. Service de Réanimation-USC de Bretagne Atlantique, Vannes, France. 55. Service de Médecine Intensive-Réanimation-Unité de Recherche Clinique Ardennes Nord, CH de Charleville-Mézieres, Charleville-Mézieres, France. 56. Intensive Care Medicine Department, Lapeyronie Hospital, University Hospital of Montpellier-PhyMedExp, University of Montpellier, INSERM, CNRS, Montpellier, France. 57. Service de Réanimation Polyvalente, CH de Chartres, Hôpital Louis Pasteur, Le Coudray, France. 58. Department of Cardiology, University Hospital, Besançon, and EA3920, University of Burgundy-Franche-Comté, Besançon, France. 59. CIC 1432, Clinical Epidemiology, University of Burgundy, Dijon, France. 60. DRCI, USMR, Francois Mitterrand University Hospital, Dijon, France. 61. Service de Médecine Légale CHU Dijon, Cellule D'Urgence Médico-Psychologique de Bourgogne Franche-Comté, Dijon, France. 62. Inserm et CHU Dijon-Bourgogne, CIC1432, Module Epidémiologie Clinique, Dijon, France. 63. Service de Médecine Intensive-Réanimation, CHU Dijon-Bourgogne, France-Equipe Lipness, centre de recherche INSERM UMR1231 et LabEx LipSTIC, Université de Bourgogne-Franche Comté, Dijon, France. jean-pierre.quenot@chu-dijon.fr. 64. INSERM, Module Épidémiologie Clinique, Université de Bourgogne Franche-Comté, CIC 1432, Dijon, France. jean-pierre.quenot@chu-dijon.fr. 65. Espace de Réflexion Éthique Bourgogne Franche-Comté (EREBFC), Besançon, France. jean-pierre.quenot@chu-dijon.fr. 66. Critical Care Department, University Hospital François Mitterrand, 14 rue Paul Gaffarel, 21079, Dijon, France. jean-pierre.quenot@chu-dijon.fr.
Abstract
BACKGROUND: We investigated the impact of the COVID-19 crisis on mental health of professionals working in the intensive care unit (ICU) according to the intensity of the epidemic in France. METHODS: This cross-sectional survey was conducted in 77 French hospitals from April 22 to May 13 2020. All ICU frontline healthcare workers were eligible. The primary endpoint was the mental health, assessed using the 12-item General Health Questionnaire. Sources of stress during the crisis were assessed using the Perceived Stressors in Intensive Care Units (PS-ICU) scale. Epidemic intensity was defined as high or low for each region based on publicly available data from Santé Publique France. Effects were assessed using linear mixed models, moderation and mediation analyses. RESULTS: In total, 2643 health professionals participated; 64.36% in high-intensity zones. Professionals in areas with greater epidemic intensity were at higher risk of mental health issues (p < 0.001), and higher levels of overall perceived stress (p < 0.001), compared to low-intensity zones. Factors associated with higher overall perceived stress were female sex (B = 0.13; 95% confidence interval [CI] = 0.08-0.17), having a relative at risk of COVID-19 (B = 0.14; 95%-CI = 0.09-0.18) and working in high-intensity zones (B = 0.11; 95%-CI = 0.02-0.20). Perceived stress mediated the impact of the crisis context on mental health (B = 0.23, 95%-CI = 0.05, 0.41) and the impact of stress on mental health was moderated by positive thinking, b = - 0.32, 95% CI = - 0.54, - 0.11. CONCLUSION: COVID-19 negatively impacted the mental health of ICU professionals. Professionals working in zones where the epidemic was of high intensity were significantly more affected, with higher levels of perceived stress. This study is supported by a grant from the French Ministry of Health (PHRC-COVID 2020).
BACKGROUND: We investigated the impact of the COVID-19 crisis on mental health of professionals working in the intensive care unit (ICU) according to the intensity of the epidemic in France. METHODS: This cross-sectional survey was conducted in 77 French hospitals from April 22 to May 13 2020. All ICU frontline healthcare workers were eligible. The primary endpoint was the mental health, assessed using the 12-item General Health Questionnaire. Sources of stress during the crisis were assessed using the Perceived Stressors in Intensive Care Units (PS-ICU) scale. Epidemic intensity was defined as high or low for each region based on publicly available data from Santé Publique France. Effects were assessed using linear mixed models, moderation and mediation analyses. RESULTS: In total, 2643 health professionals participated; 64.36% in high-intensity zones. Professionals in areas with greater epidemic intensity were at higher risk of mental health issues (p < 0.001), and higher levels of overall perceived stress (p < 0.001), compared to low-intensity zones. Factors associated with higher overall perceived stress were female sex (B = 0.13; 95% confidence interval [CI] = 0.08-0.17), having a relative at risk of COVID-19 (B = 0.14; 95%-CI = 0.09-0.18) and working in high-intensity zones (B = 0.11; 95%-CI = 0.02-0.20). Perceived stress mediated the impact of the crisis context on mental health (B = 0.23, 95%-CI = 0.05, 0.41) and the impact of stress on mental health was moderated by positive thinking, b = - 0.32, 95% CI = - 0.54, - 0.11. CONCLUSION:COVID-19 negatively impacted the mental health of ICU professionals. Professionals working in zones where the epidemic was of high intensity were significantly more affected, with higher levels of perceived stress. This study is supported by a grant from the French Ministry of Health (PHRC-COVID 2020).
Authors: Robert G Maunder; William J Lancee; Kenneth E Balderson; Jocelyn P Bennett; Bjug Borgundvaag; Susan Evans; Christopher M B Fernandes; David S Goldbloom; Mona Gupta; Jonathan J Hunter; Linda McGillis Hall; Lynn M Nagle; Clare Pain; Sonia S Peczeniuk; Glenna Raymond; Nancy Read; Sean B Rourke; Rosalie J Steinberg; Thomas E Stewart; Susan VanDeVelde-Coke; Georgina G Veldhorst; Donald A Wasylenki Journal: Emerg Infect Dis Date: 2006-12 Impact factor: 6.883
Authors: René Robert; Nancy Kentish-Barnes; Alexandre Boyer; Alexandra Laurent; Elie Azoulay; Jean Reignier Journal: Ann Intensive Care Date: 2020-06-17 Impact factor: 6.925
Authors: Mona R Loutfy; Tamara Wallington; Tim Rutledge; Barbara Mederski; Keith Rose; Sue Kwolek; Donna McRitchie; Azra Ali; Bryan Wolff; Diane White; Edward Glassman; Marianna Ofner; Don E Low; Lisa Berger; Allison McGeer; Tom Wong; David Baron; Glenn Berall Journal: Emerg Infect Dis Date: 2004-05 Impact factor: 6.883
Authors: Hernan Felipe Guillen-Burgos; Janitza Gomez-Ureche; Carlos Renowitzky; Kaleb Acevedo-Vergara; Manuel Perez-Florez; Elizabeth Villalba; Jorge Escaf; Dieb Maloof; Riguey Torrenegra; Patricia Medina; Alberto Dau; Silvia Salva; Abdel Perez; Jesus Tapia; Soraya Salcedo; Ronald Maestre; Salvador Mattar; Miguel Parra-Saavedra; Jose Torres; Cesar Mesino; Nahir Acosta; Laura Mora; Gabriel Vega; Juan Francisco Galvez-Florez Journal: J Affect Disord Rep Date: 2022-08-19