Literature DB >> 34087169

The to and fro of Rho.

Kenneth D Westover1.   

Abstract

The functions of Ras members are largely governed by the structural dynamics of the nucleotide-binding switch regions. In this issue of Structure, Lin et al. (2021) take a close look at the dynamic equilibrium of RhoA, the founding member of the Rho family of Ras GTPases.
Copyright © 2021 Elsevier Ltd. All rights reserved.

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Year:  2021        PMID： 34087169      PMCID： PMC8744210          DOI： 10.1016/j.str.2021.05.009

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  11 in total

1.  K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D.

Authors:  Jillian A Parker; Alicia Y Volmar; Spiro Pavlopoulos; Carla Mattos
Journal:  Structure       Date:  2018-04-26       Impact factor: 5.006

2.  KRASQ61H Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non-Small Cell Lung Cancer.

Authors:  Zhi-Wei Zhou; Chiara Ambrogio; Asim K Bera; Qing Li; Xing-Xiao Li; Lianbo Li; Jieun Son; Sudershan Gondi; Jiaqi Li; Emily Campbell; Hua Jin; Jeffrey J Okoro; Cheng-Xiong Xu; Pasi A Janne; Kenneth D Westover
Journal:  Cancer Res       Date:  2020-06-30       Impact factor: 12.701

Review 3.  Rho family GTPases.

Authors:  Alan Hall
Journal:  Biochem Soc Trans       Date:  2012-12-01       Impact factor: 5.407

4.  Tissue-Specific Oncogenic Activity of KRASA146T.

Authors:  Asim K Bera; Jia Lu; Emily J Poulin; Yi-Jang Lin; Samantha Dale Strasser; Joao A Paulo; Tannie Q Huang; Carolina Morales; Wei Yan; Joshua Cook; Jonathan A Nowak; Douglas K Brubaker; Brian A Joughin; Christian W Johnson; Rebecca A DeStefanis; Phaedra C Ghazi; Sudershan Gondi; Thomas E Wales; Roxana E Iacob; Lana Bogdanova; Jessica J Gierut; Yina Li; John R Engen; Pedro A Perez-Mancera; Benjamin S Braun; Steven P Gygi; Douglas A Lauffenburger; Kenneth D Westover; Kevin M Haigis
Journal:  Cancer Discov       Date:  2019-04-05       Impact factor: 39.397

Review 5.  Variegated RHOA mutations in human cancers.

Authors:  Keisuke Kataoka; Seishi Ogawa
Journal:  Exp Hematol       Date:  2016-09-29       Impact factor: 3.084

6.  KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation.

Authors:  Jia Lu; Asim K Bera; Sudershan Gondi; Kenneth D Westover
Journal:  Biochemistry       Date:  2017-12-28       Impact factor: 3.162

7.  K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.

Authors:  Jonathan M Ostrem; Ulf Peters; Martin L Sos; James A Wells; Kevan M Shokat
Journal:  Nature       Date:  2013-11-20       Impact factor: 49.962

8.  Structure of an inactive conformation of GTP-bound RhoA GTPase.

Authors:  Yuan Lin; Shaoyong Lu; Jian Zhang; Yi Zheng
Journal:  Structure       Date:  2021-01-25       Impact factor: 5.871

9.  Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma.

Authors:  Michael Krauthammer; Yong Kong; Byung Hak Ha; Perry Evans; Antonella Bacchiocchi; James P McCusker; Elaine Cheng; Matthew J Davis; Gerald Goh; Murim Choi; Stephan Ariyan; Deepak Narayan; Ken Dutton-Regester; Ana Capatana; Edna C Holman; Marcus Bosenberg; Mario Sznol; Harriet M Kluger; Douglas E Brash; David F Stern; Miguel A Materin; Roger S Lo; Shrikant Mane; Shuangge Ma; Kenneth K Kidd; Nicholas K Hayward; Richard P Lifton; Joseph Schlessinger; Titus J Boggon; Ruth Halaban
Journal:  Nat Genet       Date:  2012-07-29       Impact factor: 38.330

Review 10.  Epithelial junctions and Rho family GTPases: the zonular signalosome.

Authors:  Sandra Citi; Diego Guerrera; Domenica Spadaro; Jimit Shah
Journal:  Small GTPases       Date:  2014
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