Literature DB >> 23176484

Rho family GTPases.

Alan Hall1.   

Abstract

Rho GTPases comprise a family of molecular switches that control signal transduction pathways in eukaryotic cells. A conformational change induced upon binding GTP promotes an interaction with target (effector) proteins to generate a cellular response. A highly conserved function of Rho GTPases from yeast to humans is to control the actin cytoskeleton, although, in addition, they promote a wide range of other cellular activities. Changes in the actin cytoskeleton drive many dynamic aspects of cell behaviour, including morphogenesis, migration, phagocytosis and cytokinesis, and the dysregulation of Rho GTPases is associated with numerous human diseases and disorders.

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Year:  2012        PMID： 23176484     DOI： 10.1042/BST20120103

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  227 in total

1.  Changes in dermal matrix in the absence of Rac1 in keratinocytes.

Authors:  Alanna Stanley; Esben Pedersen; Cord Brakebusch; Fabio Quondamatteo
Journal:  J Anat       Date:  2016-02-18       Impact factor: 2.610

2.  Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1

Authors:  Julie A Mund; SuJung Park; Abbi E Smith; Yongzheng He; Li Jiang; Eric Hawley; Michelle J Roberson; Dana K Mitchell; Mohannad Abu-Sultanah; Jin Yuan; Waylan K Bessler; George Sandusky; Shi Chen; Chi Zhang; Steven D Rhodes; D Wade Clapp
Journal:  J Biol Chem       Date:  2020-05-29       Impact factor: 5.157

3.  P2Y2 nucleotide receptor activation enhances the aggregation and self-organization of dispersed salivary epithelial cells.

Authors:  Farid G El-Sayed; Jean M Camden; Lucas T Woods; Mahmoud G Khalafalla; Michael J Petris; Laurie Erb; Gary A Weisman
Journal:  Am J Physiol Cell Physiol       Date:  2014-04-23       Impact factor: 4.249

4.  Identification of emergent motion compartments in the amniote embryo.

Authors:  Rajprasad Loganathan; Charles D Little; Pranav Joshi; Michael B Filla; Tracey J Cheuvront; Rusty Lansford; Brenda J Rongish
Journal:  Organogenesis       Date:  2015-01-26       Impact factor: 2.500

5.  Vibrio cholerae T3SS effector VopE modulates mitochondrial dynamics and innate immune signaling by targeting Miro GTPases.

Authors:  Masato Suzuki; Olga Danilchanka; John J Mekalanos
Journal:  Cell Host Microbe       Date:  2014-10-23       Impact factor: 21.023

6.  ARHGEF3 controls HDACi-induced differentiation via RhoA-dependent pathways in acute myeloid leukemias.

Authors:  Loredana D'Amato; Carmela Dell'Aversana; Mariarosaria Conte; Alfonso Ciotta; Lucia Scisciola; Annamaria Carissimo; Angela Nebbioso; Lucia Altucci
Journal:  Epigenetics       Date:  2015-01-27       Impact factor: 4.528

Review 7.  Crossroads of PI3K and Rac pathways.

Authors:  Carlo C Campa; Elisa Ciraolo; Alessandra Ghigo; Giulia Germena; Emilio Hirsch
Journal:  Small GTPases       Date:  2015-05-05

8.  Protein phosphorylation during Plasmodium berghei gametogenesis.

Authors:  Alberto Alonso-Morales; Lorena González-López; Febe Elena Cázares-Raga; Leticia Cortés-Martínez; Jorge Aurelio Torres-Monzón; José Luis Gallegos-Pérez; Mario Henry Rodríguez; Anthony A James; Fidel de la Cruz Hernández-Hernández
Journal:  Exp Parasitol       Date:  2015-05-22       Impact factor: 2.011

9.  Angiopoietin-like 4 binds neuropilins and cooperates with VEGF to induce diabetic macular edema.

Authors:  Akrit Sodhi; Tao Ma; Deepak Menon; Monika Deshpande; Kathleen Jee; Aumreetam Dinabandhu; Jordan Vancel; Daoyuan Lu; Silvia Montaner
Journal:  J Clin Invest       Date:  2019-11-01       Impact factor: 14.808

Review 10.  Rho GTPases: Regulation and roles in cancer cell biology.

Authors:  Raquel B Haga; Anne J Ridley
Journal:  Small GTPases       Date:  2016-09-14
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