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Literature DB >> 3408636

Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.

S Mousdale¹, P A Clyburn, A M Mackie, N D Groves, M Rosen.

Abstract

1. We compared the effects of dopexamine, dopamine and dobutamine on the heart rate, blood pressure and renal blood flow of six healthy volunteers in an open triple crossover trial. 2. The results suggest that at the dose ranges investigated dopamine was the most effective agent for increasing renal blood flow.

Entities: Chemical

Mesh：

Substances：

Year: 1988 PMID： 3408636 PMCID： PMC1386428 DOI： 10.1111/j.1365-2125.1988.tb03345.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

9 in total

Review 1. Vasodilator therapy of cardiac failure (second of two parts).

Authors: J N Cohn; J A Franciosa
Journal: N Engl J Med Date: 1977-08-04 Impact factor: 91.245

2. Effective renal plasma flow: estimation from theoretical volumes of distribution of intravenously injected 131-I orthoiodohippurate.

Authors: W N Tauxe; F T Maher; W F Taylor
Journal: Mayo Clin Proc Date: 1971-08 Impact factor: 7.616

3. Correlation of renal blood flow determined by the single injection of Hippuran-I 131 with direct measurements of flow.

Authors: W H Pritchard; R W Eckstein; W J MacIntyre; E Dabaj
Journal: Am Heart J Date: 1965-12 Impact factor: 4.749

4. Comparison of measurement of effective renal plasma flow by single plasma sample and plasma disappearance slope/volume methods.

Authors: W N Tauxe; E V Dubovsky; T E Kidd
Journal: Eur J Nucl Med Date: 1984

5. Acute haemodynamic and metabolic effects of dopexamine, a new dopaminergic receptor agonist, in patients with chronic heart failure.

Authors: J R Dawson; D S Thompson; M Signy; S M Juul; P Turnbull; B S Jenkins; M M Webb-Peploe
Journal: Br Heart J Date: 1985-09

5 in total

Review 5. Dopexamine hydrochloride. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in acute cardiac insufficiency.

Authors: A Fitton; P Benfield
Journal: Drugs Date: 1990-02 Impact factor: 9.546

5 in total

Comparison of the effects of dopamine, dobutamine, and dopexamine upon renal blood flow: a study in normal healthy volunteers.

Review 1. Vasodilator therapy of cardiac failure (second of two parts).

2. Effective renal plasma flow: estimation from theoretical volumes of distribution of intravenously injected 131-I orthoiodohippurate.

3. Correlation of renal blood flow determined by the single injection of Hippuran-I 131 with direct measurements of flow.

4. Comparison of measurement of effective renal plasma flow by single plasma sample and plasma disappearance slope/volume methods.

5. Acute haemodynamic and metabolic effects of dopexamine, a new dopaminergic receptor agonist, in patients with chronic heart failure.

6. Serial measurement of renal plasma flow.

7. The effects of dopexamine on the cardiovascular system of the dog.

8. The haemodynamic and myocardial effects of dopexamine: a new beta 2-adrenoceptor and dopaminergic agonist.

9. Short-term haemodynamic effects of dopexamine in patients with chronic congestive heart failure.

Review 1. Use of inotropes and vasopressor agents in critically ill patients.

2. Vasodilator responses to dopamine in rat perfused mesentery are age-dependent.

3. Circulatory and diuretic effects of dopexamine infusion in low-birth-weight infants with respiratory failure.

4. Renal effect of dopexamine hydrochloride in patients with chronic renal dysfunction.

Review 5. Dopexamine hydrochloride. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in acute cardiac insufficiency.