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Literature DB >> 3408475

Nucleotide sequence of the human theta 1-globin gene.

J M Gonzalez-Redondo¹, I S Han, Y C Gu, T H Huisman.

Abstract

We have cloned and sequenced the human theta 1-globin gene. The nucleotide sequence and organization of the human theta 1 gene (exons, introns, promoter, and polyadenylation signals) are similar to those reported for the orangutan theta 1-globin gene. If these genes are functional, the sequences of their theta 1-globin chains would differ by only one amino acid residue (at position 137).

Entities: Gene Species

Mesh：

Substances：
Globins

Year: 1988 PMID： 3408475 DOI： 10.1007/bf00561460

Source DB: PubMed Journal: Biochem Genet ISSN： 0006-2928 Impact factor: 1.890

16 in total

1. Two different theta (theta) globin gene deletions observed among black newborn babies.

Authors: Y J Fei; S Fujita; T H Huisman
Journal: Br J Haematol Date: 1988-02 Impact factor: 6.998

2. Function of a new globin gene.

Authors: N Fischel-Ghodsian; D R Higgs; E C Beyer
Journal: Nature Date: 1987 Oct 1-7 Impact factor: 49.962

3. The gene for theta-globin is transcribed in human fetal erythroid tissues.

Authors: S Leung; N J Proudfoot; E Whitelaw
Journal: Nature Date: 1987 Oct 8-14 Impact factor: 49.962

4. Primate evolution of the alpha-globin gene cluster and its Alu-like repeats.

Authors: I Sawada; C W Schmid
Journal: J Mol Biol Date: 1986-12-20 Impact factor: 5.469

5. DNA sequence analysis by primed synthesis.

Authors: A J Smith
Journal: Methods Enzymol Date: 1980 Impact factor: 1.600

6. Isolation and nucleotide sequence of the rabbit globin gene cluster psi zeta-alpha 1-psi alpha. Absence of a pair of alpha-globin genes evolving in concert.

Authors: J F Cheng; L Raid; R C Hardison
Journal: J Biol Chem Date: 1986-01-15 Impact factor: 5.157

Nucleotide sequence of the human theta 1-globin gene.

1. Two different theta (theta) globin gene deletions observed among black newborn babies.

2. Function of a new globin gene.

3. The gene for theta-globin is transcribed in human fetal erythroid tissues.

4. Primate evolution of the alpha-globin gene cluster and its Alu-like repeats.

5. DNA sequence analysis by primed synthesis.

6. Isolation and nucleotide sequence of the rabbit globin gene cluster psi zeta-alpha 1-psi alpha. Absence of a pair of alpha-globin genes evolving in concert.

7. Sequence organization and genomic complexity of primate theta 1 globin gene, a novel alpha-globin-like gene.

8. Evidence that the recently discovered theta 1-globin gene is functional in higher primates.

9. The chromosomal arrangement of human alpha-like globin genes: sequence homology and alpha-globin gene deletions.

10. DNA sequencing with chain-terminating inhibitors.

1. The levels of zeta, gamma, and delta chains in patients with Hb H disease.