Literature DB >> 34080093

Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials.

Geetanjali Saini1, Keerthi Gogineni2, Rick A Kittles3, Ritu Aneja4.   

Abstract

Precision (or personalized) medicine holds great promise in the treatment of breast cancer. The success of personalized medicine is contingent upon inclusivity and representation for minority groups in clinical trials. In this article, we focus on the roadblocks for the African American demographic, including the barriers to access and enrollment in breast oncology trials, the prevailing classification of race and ethnicity, and the need to refine monolithic categorization by employing genetic ancestry mapping tools for a more accurate determination of race or ethnicity.

Entities:  

Keywords:  African Americans; Ancestry informative markers; Oncology trials; Race/ethnicity classification

Mesh：

Year:  2021        PMID： 34080093     DOI： 10.1007/s10549-021-06264-x

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN： 0167-6806            Impact factor:   4.872


  59 in total

1.  Willingness of minorities to participate in biomedical studies: confirmatory findings from a follow-up study using the Tuskegee Legacy Project Questionnaire.

Authors:  Ralph V Katz; B Lee Green; Nancy R Kressin; Cristina Claudio; Min Qi Wang; Stefanie L Russell
Journal:  J Natl Med Assoc       Date:  2007-09       Impact factor: 1.798

Review 2.  Ethnic differences in drug metabolism and toxicity from chemotherapy.

Authors:  Viet Hong Phan; Melissa M Moore; Andrew J McLachlan; Micheline Piquette-Miller; Hongmei Xu; Stephen J Clarke
Journal:  Expert Opin Drug Metab Toxicol       Date:  2009-03       Impact factor: 4.481

Review 3.  Diabetes in African Americans.

Authors:  M C Marshall
Journal:  Postgrad Med J       Date:  2005-12       Impact factor: 2.401

4.  Disparities in diabetes-related multiple chronic conditions and mortality: The influence of race.

Authors:  John M Clements; Brady T West; Zachary Yaker; Breanna Lauinger; Deven McCullers; James Haubert; Mohammad Ali Tahboub; Gregory J Everett
Journal:  Diabetes Res Clin Pract       Date:  2019-12-15       Impact factor: 5.602

Review 5.  Enrollment of Racial Minorities in Clinical Trials: Old Problem Assumes New Urgency in the Age of Immunotherapy.

Authors:  Bassel Nazha; Manoj Mishra; Rebecca Pentz; Taofeek K Owonikoko
Journal:  Am Soc Clin Oncol Educ Book       Date:  2019-05-17

Review 6.  Ethnic distinctions in the pathophysiology of type 2 diabetes: a focus on black African-Caribbean populations.

Authors:  Louise M Goff; Meera Ladwa; Olah Hakim; Oluwatoyosi Bello
Journal:  Proc Nutr Soc       Date:  2019-07-16       Impact factor: 6.297

7.  The More Things Change, the More They Stay the Same: A Study to Evaluate Compliance With Inclusion and Assessment of Women and Minorities in Randomized Controlled Trials.

Authors:  Stacie E Geller; Abigail R Koch; Pamela Roesch; Amarette Filut; Emily Hallgren; Molly Carnes
Journal:  Acad Med       Date:  2018-04       Impact factor: 6.893

Review 8.  Twenty years post-NIH Revitalization Act: enhancing minority participation in clinical trials (EMPaCT): laying the groundwork for improving minority clinical trial accrual: renewing the case for enhancing minority participation in cancer clinical trials.

Authors:  Moon S Chen; Primo N Lara; Julie H T Dang; Debora A Paterniti; Karen Kelly
Journal:  Cancer       Date:  2014-04-01       Impact factor: 6.860

Review 9.  Are racial and ethnic minorities less willing to participate in health research?

Authors:  David Wendler; Raynard Kington; Jennifer Madans; Gretchen Van Wye; Heidi Christ-Schmidt; Laura A Pratt; Otis W Brawley; Cary P Gross; Ezekiel Emanuel
Journal:  PLoS Med       Date:  2005-12-06       Impact factor: 11.069

10.  Quadruple-Negative Breast Cancer: An Uneven Playing Field.

Authors:  Geetanjali Saini; Shristi Bhattarai; Keerthi Gogineni; Ritu Aneja
Journal:  JCO Glob Oncol       Date:  2020-02
View more
  1 in total

Review 1.  The influence of telehealth-based cancer rehabilitation interventions on disability: a systematic review.

Authors:  Rachelle Brick; Lynne Padgett; Jennifer Jones; Kelley Covington Wood; Mackenzi Pergolotti; Timothy F Marshall; Grace Campbell; Rachel Eilers; Sareh Keshavarzi; Ann Marie Flores; Julie K Silver; Aneesha Virani; Alicia A Livinski; Mohammed Faizan Ahmed; Tiffany Kendig; Bismah Khalid; Jeremy Barnett; Anita Borhani; Graysen Bernard; Kathleen Doyle Lyons
Journal:  J Cancer Surviv       Date:  2022-02-26       Impact factor: 4.442
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.