Literature DB >> 34079713

Association between spinal alignment and biochemical composition of lumbar intervertebral discs assessed by quantitative magnetic resonance imaging.

Rafael Menezes-Reis1,2, Carlos E Garrido Salmon3, Gustavo P Bonugli1, Debora Mazoroski1, Leonor G Savarese1, Carlos Fernando P S Herrero1, Helton L A Defino1, Marcello Henrique Nogueira-Barbosa1.   

Abstract

BACKGROUND: To evaluate potential associations between spinopelvic parameters and the biochemical composition of lumbar intervertebral discs using quantitative magnetic resonance imaging in asymptomatic young adults.
METHODS: Our study group comprised 93 asymptomatic volunteers aged 20-40 years (49 women and 44 men). Lumbar spine T2-weighted images and T2 relaxometry were acquired on a 1.5T MRI scanner. Spinopelvic parameters including sacral slope, pelvic tilt, pelvic incidence, lumbar lordosis, thoracic kyphosis, thoracolumbar alignment, sagittal vertical axis, spinosacral angle, C2 pelvic angle, and T1S1 and L1S1 length were measured on panoramic spine radiographs.
RESULTS: Lumbar lordosis decrease correlates with discrete dehydration of nucleus pulposus at all lumbar levels. Also low values of sacral slope, pelvic tilt, pelvic incidence, thoracic kyphosis and spinosacral angle were associated with decrease of T2 relaxation times on annulus fibrosus.
CONCLUSIONS: In conclusion, spinopelvic parameters presented a discrete association with lumbar disc composition and water content. 2021 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Entities:  

Keywords:  Intervertebral disc; lumbosacral region; magnetic resonance imaging; posture; spine

Year:  2021        PMID: 34079713      PMCID: PMC8107339          DOI: 10.21037/qims-20-40

Source DB:  PubMed          Journal:  Quant Imaging Med Surg        ISSN: 2223-4306


  49 in total

1.  Effect of aging and degeneration on disc volume and shape: A quantitative study in asymptomatic volunteers.

Authors:  Christian W A Pfirrmann; Alexander Metzdorf; Achim Elfering; Juerg Hodler; Norbert Boos
Journal:  J Orthop Res       Date:  2006-05       Impact factor: 3.494

2.  The Influence of Lumbar Spinal Subtype on Lumbar Intervertebral Disc Degeneration in Young and Middle-Aged Adults.

Authors:  P A G Torrie; G McKay; R Byrne; S A C Morris; I J Harding
Journal:  Spine Deform       Date:  2015-03-04

3.  Does lumbar disc degeneration on magnetic resonance imaging associate with low back symptom severity in young Finnish adults?

Authors:  Jani Takatalo; Jaro Karppinen; Jaakko Niinimäki; Simo Taimela; Simo Näyhä; Pertti Mutanen; Roberto Blanco Sequeiros; Eero Kyllönen; Osmo Tervonen
Journal:  Spine (Phila Pa 1976)       Date:  2011-12-01       Impact factor: 3.468

4.  Alterations of ADAMTSs and TIMP-3 in human nucleus pulposus cells subjected to compressive load: Implications in the pathogenesis of human intervertebral disc degeneration.

Authors:  Ming Huang; Hai-Qiang Wang; Qiang Zhang; Xiao-Dong Yan; Meng Hao; Zhuo-Jing Luo
Journal:  J Orthop Res       Date:  2011-08-01       Impact factor: 3.494

5.  Classification of the normal variation in the sagittal alignment of the human lumbar spine and pelvis in the standing position.

Authors:  Pierre Roussouly; Sohrab Gollogly; Eric Berthonnaud; Johanes Dimnet
Journal:  Spine (Phila Pa 1976)       Date:  2005-02-01       Impact factor: 3.468

6.  The effects of age, sex, ethnicity, and spinal level on the rate of intervertebral disc degeneration: a review of 1712 intervertebral discs.

Authors:  Krzysztof Siemionow; Howard An; Koichi Masuda; Gunnar Andersson; Gabriella Cs-Szabo
Journal:  Spine (Phila Pa 1976)       Date:  2011-08-01       Impact factor: 3.468

7.  Which lateral radiographic positioning technique provides the most reliable and functional representation of a patient's sagittal balance?

Authors:  Michelle Marks; Chriss Stanford; Peter Newton
Journal:  Spine (Phila Pa 1976)       Date:  2009-04-20       Impact factor: 3.468

8.  Heritability of spinal curvature and its relationship to disc degeneration and bone mineral density in female adult twins.

Authors:  Millicent A Stone; Daniel-Clement Osei-Bordom; Robert D Inman; Cormac Sammon; Lisa E Wolber; Frances M K Williams
Journal:  Eur Spine J       Date:  2014-07-29       Impact factor: 3.134

Review 9.  Quantitative MRI as a diagnostic tool of intervertebral disc matrix composition and integrity.

Authors:  Fackson Mwale; James C Iatridis; John Antoniou
Journal:  Eur Spine J       Date:  2008-11-13       Impact factor: 3.134

10.  Body mass index is associated with lumbar disc degeneration in young Finnish males: subsample of Northern Finland birth cohort study 1986.

Authors:  Jani Takatalo; Jaro Karppinen; Simo Taimela; Jaakko Niinimäki; Jaana Laitinen; Roberto Blanco Sequeiros; Markus Paananen; Jouko Remes; Simo Näyhä; Tuija Tammelin; Raija Korpelainen; Osmo Tervonen
Journal:  BMC Musculoskelet Disord       Date:  2013-03-11       Impact factor: 2.362

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  1 in total

1.  Radiographic study of peak velocity of pelvic incidence in adolescent idiopathic scoliosis.

Authors:  Yuancheng Zhang; Shibin Shu; Qi Gu; Filippo Mandelli; Tianyuan Zhang; Wenting Jing; Yong Qiu; Zezhang Zhu; Hongda Bao
Journal:  Quant Imaging Med Surg       Date:  2022-02
  1 in total

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