Literature DB >> 34077715

A newly identified protein from Akkermansia muciniphila stimulates GLP-1 secretion.

Patrice D Cani1, Claude Knauf2.   

Abstract

Akkermansia muciniphila is a gut commensal known to improve host metabolism. The outer membrane protein Amuc_1100 has been shown to partially replicate these beneficial effects. Here, Yoon et al. (2021) have identified a novel protein (P9) secreted by A. muciniphila that stimulates GLP-1 secretion, thereby adding new insight to the biomolecule era to treat metabolic diseases.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Year:  2021        PMID： 34077715     DOI： 10.1016/j.cmet.2021.05.004

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  7 in total

1.  Akkermansia muciniphila: is it the Holy Grail for ameliorating metabolic diseases?

Authors:  Juan Yan; Lili Sheng; Houkai Li
Journal:  Gut Microbes       Date:  2021 Jan-Dec

Review 2.  Gut microbes and food reward: From the gut to the brain.

Authors:  Alice de Wouters d'Oplinter; Sabrina J P Huwart; Patrice D Cani; Amandine Everard
Journal:  Front Neurosci       Date:  2022-07-25       Impact factor: 5.152

3.  Bacillus coagulans in Combination with Chitooligosaccharides Regulates Gut Microbiota and Ameliorates the DSS-Induced Colitis in Mice.

Authors:  Zhenzhen Liu; Ziyang Jiang; Zhenting Zhang; Tong Liu; Yurong Fan; Tao Liu; Nan Peng
Journal:  Microbiol Spectr       Date:  2022-07-28

Review 4.  Time-limited diets and the gut microbiota in cardiometabolic disease.

Authors:  Karina Ratiner; Hagit Shapiro; Kim Goldenberg; Eran Elinav
Journal:  J Diabetes       Date:  2022-06-13       Impact factor: 4.530

Review 5.  Gut microbiota: A new target for T2DM prevention and treatment.

Authors:  Lulu Liu; Jiheng Zhang; Yi Cheng; Meng Zhu; Zhifeng Xiao; Guangcong Ruan; Yanling Wei
Journal:  Front Endocrinol (Lausanne)       Date:  2022-08-11       Impact factor: 6.055

6.  Pasteurized Akkermansia muciniphila Reduces Fat Accumulation via nhr-49-Mediated Nuclear Hormone Signaling Pathway in Caenorhabditis elegans.

Authors:  Zhongqin Wu; Yu Xiao; Fang Zhou; Jiaxu Chen; Xinming Chen; Aixiang Hou; Yuanliang Wang; Zongjun Li
Journal:  Molecules       Date:  2022-09-20       Impact factor: 4.927

Review 7.  Gut microbiome and health: mechanistic insights.

Authors:  Willem M de Vos; Herbert Tilg; Matthias Van Hul; Patrice D Cani
Journal:  Gut       Date:  2022-02-01       Impact factor: 23.059
  7 in total

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