Literature DB >> 34073792

Analysis of Mercury in Skin Lightening Cream by Microwave Plasma Atomic Emission Spectroscopy (MP-AES).

Hardoko I Qudus1, Purwadi Purwadi2, Iis Holilah3, Sutopo Hadi1.   

Abstract

This research aimed at developing an analysis method, which was optimized and validated to determine the content of mercury in skin lightening cream discovered in the market in Bandar Lampung, Indonesia, through the use of microwave plasma atomic emission spectroscopy (MP-AES). The optimization on the analysis method was conducted on pump rate, viewing position, and reductant concentration in order to obtain the highest mercury emission intensity, while the solution stability was optimized to know the stability of mercury in the solution. The result showed that the method developed had precision with a relative standard deviation of 2.67%, recovery value of 92.78%, and linearity with an r value of 0.993, respectively. The sensitivity of the instrument detection had a limit of analysis method detection and quantification of 0.59 and 1.98 µg/L, respectively. The results of the test of the lightening cream (8 of 16 samples) positively contained mercury in the range of 422.61-44,960.79 ng/g. Therefore the method of analysis developed may be used for routine analysis of chemicals in any cosmetics products.

Entities:  

Keywords:  MP-AES; analytical method validation; mercury; skin lightening cream

Year:  2021        PMID: 34073792     DOI: 10.3390/molecules26113130

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.411


  8 in total

Review 1.  The toxicology of mercury and its chemical compounds.

Authors:  Thomas W Clarkson; Laszlo Magos
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Review 2.  Widespread use of toxic skin lightening compounds: medical and psychosocial aspects.

Authors:  Barry Ladizinski; Nisha Mistry; Roopal V Kundu
Journal:  Dermatol Clin       Date:  2010-10-13       Impact factor: 3.478

3.  Comparison of MP AES and ICP-MS for analysis of principal and selected trace elements in nitric acid digests of sunflower (Helianthus annuus).

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Journal:  Talanta       Date:  2014-12-24       Impact factor: 6.057

4.  Application of microwave plasma atomic emission spectrometry (MP-AES) for environmental monitoring of industrially contaminated sites in Hyderabad city.

Authors: 
Journal:  Environ Monit Assess       Date:  2014-08-03       Impact factor: 2.513

Review 5.  Peripheral neuropathy: pathogenic mechanisms and alternative therapies.

Authors:  Kathleen A Head
Journal:  Altern Med Rev       Date:  2006-12

6.  Chemical toxicity prediction for major classes of industrial chemicals: Is it possible to develop universal models covering cosmetics, drugs, and pesticides?

Authors:  Vinicius M Alves; Eugene N Muratov; Alexey Zakharov; Nail N Muratov; Carolina H Andrade; Alexander Tropsha
Journal:  Food Chem Toxicol       Date:  2017-04-12       Impact factor: 6.023

7.  Evaluation of heavy metals in cosmetic products and their health risk assessment.

Authors:  Hamna Arshad; Moniba Zahid Mehmood; Munir Hussain Shah; Arshad Mehmood Abbasi
Journal:  Saudi Pharm J       Date:  2020-05-29       Impact factor: 4.330

8.  Optimization of instrument conditions for the analysis for mercury, arsenic, antimony and selenium by atomic absorption spectroscopy.

Authors:  Elisabeth Mohammed; Terry Mohammed; Azad Mohammed
Journal:  MethodsX       Date:  2018-07-29
  8 in total

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