Literature DB >> 34067395

Epithelial to Mesenchymal Transition History: From Embryonic Development to Cancers.

Camille Lachat1, Paul Peixoto1,2, Eric Hervouet1,2,3.   

Abstract

Epithelial to mesenchymal transition (EMT) is a process that allows epithelial cells to progressively acquire a reversible mesenchymal phenotype. Here, we recount the main events in the history of EMT. EMT was first studied during embryonic development. Nowadays, it is an important field in cancer research, studied all around the world by more and more scientists, because it was shown that EMT is involved in cancer aggressiveness in many different ways. The main features of EMT's involvement in embryonic development, fibrosis and cancers are briefly reviewed here.

Entities:  

Keywords:  EMT; cancer; development

Year:  2021        PMID： 34067395     DOI： 10.3390/biom11060782

Source DB:  PubMed          Journal:  Biomolecules        ISSN： 2218-273X


  142 in total

Review 1.  Mesenchymal-to-epithelial transition during somitic segmentation: a novel approach to studying the roles of Rho family GTPases in morphogenesis.

Authors:  Yoshiko Takahashi; Yuki Sato; Rinako Suetsugu; Yukiko Nakaya
Journal:  Cells Tissues Organs       Date:  2005       Impact factor: 2.481

2.  TGF beta-mediated RhoA expression is necessary for epithelial-mesenchymal transition in the embryonic chick heart.

Authors:  André Luiz P Tavares; Melania E Mercado-Pimentel; Raymond B Runyan; Gregory T Kitten
Journal:  Dev Dyn       Date:  2006-06       Impact factor: 3.780

3.  Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.

Authors:  Oscar H Ocaña; Rebeca Córcoles; Angels Fabra; Gema Moreno-Bueno; Hervé Acloque; Sonia Vega; Alejandro Barrallo-Gimeno; Amparo Cano; M Angela Nieto
Journal:  Cancer Cell       Date:  2012-11-29       Impact factor: 31.743

4.  Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo.

Authors:  X Sun; E N Meyers; M Lewandoski; G R Martin
Journal:  Genes Dev       Date:  1999-07-15       Impact factor: 11.361

5.  DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells.

Authors:  Andreas Eger; Kirsten Aigner; Stefan Sonderegger; Brigitta Dampier; Susanne Oehler; Martin Schreiber; Geert Berx; Amparo Cano; Hartmut Beug; Roland Foisner
Journal:  Oncogene       Date:  2005-03-31       Impact factor: 9.867

Review 6.  EMT and Cancer: More Than Meets the Eye.

Authors:  Rik Derynck; Robert A Weinberg
Journal:  Dev Cell       Date:  2019-05-06       Impact factor: 12.270

7.  Insulin-like growth factor-I-dependent up-regulation of ZEB1 drives epithelial-to-mesenchymal transition in human prostate cancer cells.

Authors:  Tisheeka R Graham; Haiyen E Zhau; Valerie A Odero-Marah; Adeboye O Osunkoya; K Sean Kimbro; Mourad Tighiouart; Tongrui Liu; Jonathan W Simons; Ruth M O'Regan
Journal:  Cancer Res       Date:  2008-04-01       Impact factor: 12.701

8.  Tumor microenvironment regulates epithelial-mesenchymal transitions in metastasis.

Authors:  Dingcheng Gao; Vivek Mittal
Journal:  Expert Rev Anticancer Ther       Date:  2012-07       Impact factor: 4.512

9.  The epithelial-mesenchymal transition generates cells with properties of stem cells.

Authors:  Sendurai A Mani; Wenjun Guo; Mai-Jing Liao; Elinor Ng Eaton; Ayyakkannu Ayyanan; Alicia Y Zhou; Mary Brooks; Ferenc Reinhard; Cheng Cheng Zhang; Michail Shipitsin; Lauren L Campbell; Kornelia Polyak; Cathrin Brisken; Jing Yang; Robert A Weinberg
Journal:  Cell       Date:  2008-05-16       Impact factor: 41.582

10.  Sip1 mediates an E-cadherin-to-N-cadherin switch during cranial neural crest EMT.

Authors:  Crystal D Rogers; Ankur Saxena; Marianne E Bronner
Journal:  J Cell Biol       Date:  2013-12-02       Impact factor: 10.539
View more
  4 in total

Review 1.  Epithelial-mesenchymal transition: The history, regulatory mechanism, and cancer therapeutic opportunities.

Authors:  Zhao Huang; Zhe Zhang; Chengwei Zhou; Lin Liu; Canhua Huang
Journal:  MedComm (2020)       Date:  2022-05-18

2.  Biochanin A Suppresses Tumor Progression and PD-L1 Expression via Inhibiting ZEB1 Expression in Colorectal Cancer.

Authors:  Junying Xu; Xuejing Yang; Jiadong Pan; Honghong Fan; Jie Mei; Dong Hua
Journal:  J Oncol       Date:  2022-02-22       Impact factor: 4.375

3.  MiR-150-5p Overexpression in Triple-Negative Breast Cancer Contributes to the In Vitro Aggressiveness of This Breast Cancer Subtype.

Authors:  Bruna M Sugita; Yara Rodriguez; Aline S Fonseca; Emanuelle Nunes Souza; Bhaskar Kallakury; Iglenir J Cavalli; Enilze M S F Ribeiro; Ritu Aneja; Luciane R Cavalli
Journal:  Cancers (Basel)       Date:  2022-04-26       Impact factor: 6.639

Review 4.  The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment.

Authors:  Hannah Cessna; Stavroula Baritaki; Apostolos Zaravinos; Benjamin Bonavida
Journal:  Cancers (Basel)       Date:  2022-09-22       Impact factor: 6.575
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.