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Literature DB >> 31063750

EMT and Cancer: More Than Meets the Eye.

Abstract

Epithelial cells acquire mesenchymal characteristics during development, wound healing and inflammation, and in cancer and fibrosis. With increasing appreciation of different roles of epithelial-mesenchymal transition (EMT), we address the question of how to define and recognize EMT processes and discuss their properties in cancer progression.

Entities: Disease Gene Species

Mesh：

Year: 2019 PMID： 31063750 PMCID： PMC7672963 DOI： 10.1016/j.devcel.2019.04.026

Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270

16 in total

1. Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition.

Authors: Yoko Katsuno; Dominique Stephan Meyer; Ziyang Zhang; Kevan M Shokat; Rosemary J Akhurst; Kohei Miyazono; Rik Derynck
Journal: Sci Signal Date: 2019-02-26 Impact factor: 8.192

Review 2. A common framework for EMT and collective cell migration.

Authors: Kyra Campbell; Jordi Casanova
Journal: Development Date: 2016-12-01 Impact factor: 6.868

3. EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration.

Authors: Nicole M Aiello; Ravikanth Maddipati; Robert J Norgard; David Balli; Jinyang Li; Salina Yuan; Taiji Yamazoe; Taylor Black; Amine Sahmoud; Emma E Furth; Dafna Bar-Sagi; Ben Z Stanger
Journal: Dev Cell Date: 2018-06-18 Impact factor: 12.270

4. Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas.

Authors: Anushka Dongre; Mohammad Rashidian; Ferenc Reinhardt; Aaron Bagnato; Zuzana Keckesova; Hidde L Ploegh; Robert A Weinberg
Journal: Cancer Res Date: 2017-04-20 Impact factor: 12.701

5. Slug and Sox9 cooperatively determine the mammary stem cell state.

Authors: Wenjun Guo; Zuzana Keckesova; Joana Liu Donaher; Tsukasa Shibue; Verena Tischler; Ferenc Reinhardt; Shalev Itzkovitz; Aurelia Noske; Ursina Zürrer-Härdi; George Bell; Wai Leong Tam; Sendurai A Mani; Alexander van Oudenaarden; Robert A Weinberg
Journal: Cell Date: 2012-03-02 Impact factor: 41.582

Review 6. Molecular mechanisms of epithelial-mesenchymal transition.

Authors: Samy Lamouille; Jian Xu; Rik Derynck
Journal: Nat Rev Mol Cell Biol Date: 2014-03 Impact factor: 94.444

Review 7. Therapy resistance mediated by cancer stem cells.

Authors: Teresa Bernadette Steinbichler; József Dudás; Sergej Skvortsov; Ute Ganswindt; Herbert Riechelmann; Ira-Ida Skvortsova
Journal: Semin Cancer Biol Date: 2018-11-22 Impact factor: 15.707

Review 8. Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection.

Authors: Shomyseh Sanjabi; Soyoung A Oh; Ming O Li
Journal: Cold Spring Harb Perspect Biol Date: 2017-06-01 Impact factor: 10.005

Review 9. EMT, CSCs, and drug resistance: the mechanistic link and clinical implications.

Authors: Tsukasa Shibue; Robert A Weinberg
Journal: Nat Rev Clin Oncol Date: 2017-04-11 Impact factor: 66.675

Review 10. EMT Transition States during Tumor Progression and Metastasis.

Authors: Ievgenia Pastushenko; Cédric Blanpain
Journal: Trends Cell Biol Date: 2018-12-26 Impact factor: 20.808

88 in total

Review 1. TGFβ biology in cancer progression and immunotherapy.

Authors: Rik Derynck; Shannon J Turley; Rosemary J Akhurst
Journal: Nat Rev Clin Oncol Date: 2020-07-24 Impact factor: 66.675

2. HOXB5 promotes malignant progression in pancreatic cancer via the miR-6732 pathway.

Authors: Zhi-Xi Li; Gang Wu; Wen-Jun Jiang; Jie Li; You-Yu Wang; Xue-Ming Ju; Yan-Tao Yin
Journal: Cell Cycle Date: 2019-12-26 Impact factor: 4.534

3. From Proteomic Mapping to Invasion-Metastasis-Cascade Systemic Biomarkering and Targeted Drugging of Mutant BRAF-Dependent Human Cutaneous Melanomagenesis.

Authors: Aikaterini F Giannopoulou; Athanassios D Velentzas; Athanasios K Anagnostopoulos; Adamantia Agalou; Nikos C Papandreou; Stamatia A Katarachia; Dimitra G Koumoundourou; Eumorphia G Konstantakou; Vasiliki I Pantazopoulou; Anastasios Delis; Maria T Michailidi; Dimitrios Valakos; Dimitris Chatzopoulos; Popi Syntichaki; Vassiliki A Iconomidou; Ourania E Tsitsilonis; Issidora S Papassideri; Gerassimos E Voutsinas; Polydefkis Hatzopoulos; Dimitris Thanos; Dimitris Beis; Ema Anastasiadou; George Th Tsangaris; Dimitrios J Stravopodis
Journal: Cancers (Basel) Date: 2021-04-22 Impact factor: 6.639

Review 4. Regulation of breast cancer metastasis signaling by miRNAs.

Authors: Belinda J Petri; Carolyn M Klinge
Journal: Cancer Metastasis Rev Date: 2020-09 Impact factor: 9.264

Review 5. Tumor Plasticity and Resistance to Immunotherapy.

Authors: Lucas A Horn; Kristen Fousek; Claudia Palena
Journal: Trends Cancer Date: 2020-03-04

6. Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-β1 secretion.

Authors: Megan E Martin; Denise K Reaves; Breanna Jeffcoat; Jeffrey R Enders; Lindsey M Costantini; Susan T Yeyeodu; Diane Botta; Terrance J Kavanagh; Jodie M Fleming
Journal: Nanomedicine Date: 2019-07-24 Impact factor: 5.307

Review 7. Tumour budding in solid cancers.

Authors: Alessandro Lugli; Inti Zlobec; Martin D Berger; Richard Kirsch; Iris D Nagtegaal
Journal: Nat Rev Clin Oncol Date: 2020-09-08 Impact factor: 66.675