Literature DB >> 34067344

Detection of Anomalous Diffusion with Deep Residual Networks.

Miłosz Gajowczyk1, Janusz Szwabiński1.   

Abstract

Identification of the diffusion type of molecules in living cells is crucial to deduct their driving forces and hence to get insight into the characteristics of the cells. In this paper, deep residual networks have been used to classify the trajectories of molecules. We started from the well known ResNet architecture, developed for image classification, and carried out a series of numerical experiments to adapt it to detection of diffusion modes. We managed to find a model that has a better accuracy than the initial network, but contains only a small fraction of its parameters. The reduced size significantly shortened the training time of the model. Moreover, the resulting network has less tendency to overfitting and generalizes better to unseen data.

Entities:  

Keywords:  SPT; anomalous diffusion; deep learning; machine learning classification; residual neural networks

Year:  2021        PMID: 34067344     DOI: 10.3390/e23060649

Source DB:  PubMed          Journal:  Entropy (Basel)        ISSN: 1099-4300            Impact factor:   2.524


  48 in total

1.  Optimal and suboptimal quadratic forms for noncentered Gaussian processes.

Authors:  Denis S Grebenkov
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2013-09-27

2.  Effect of separate sampling on classification accuracy.

Authors:  Mohammad Shahrokh Esfahani; Edward R Dougherty
Journal:  Bioinformatics       Date:  2013-11-20       Impact factor: 6.937

3.  Statistical testing approach for fractional anomalous diffusion classification.

Authors:  Aleksander Weron; Joanna Janczura; Ewa Boryczka; Titiwat Sungkaworn; Davide Calebiro
Journal:  Phys Rev E       Date:  2019-04       Impact factor: 2.529

4.  Classification of particle trajectories in living cells: Machine learning versus statistical testing hypothesis for fractional anomalous diffusion.

Authors:  Joanna Janczura; Patrycja Kowalek; Hanna Loch-Olszewska; Janusz Szwabiński; Aleksander Weron
Journal:  Phys Rev E       Date:  2020-09       Impact factor: 2.529

5.  Classification of diffusion modes in single-particle tracking data: Feature-based versus deep-learning approach.

Authors:  Patrycja Kowalek; Hanna Loch-Olszewska; Janusz Szwabiński
Journal:  Phys Rev E       Date:  2019-09       Impact factor: 2.529

6.  Measurement of anomalous diffusion using recurrent neural networks.

Authors:  Stefano Bo; Falko Schmidt; Ralf Eichhorn; Giovanni Volpe
Journal:  Phys Rev E       Date:  2019-07       Impact factor: 2.529

7.  Understanding individual human mobility patterns.

Authors:  Marta C González; César A Hidalgo; Albert-László Barabási
Journal:  Nature       Date:  2008-06-05       Impact factor: 49.962

Review 8.  Non-Brownian diffusion in lipid membranes: Experiments and simulations.

Authors:  R Metzler; J-H Jeon; A G Cherstvy
Journal:  Biochim Biophys Acta       Date:  2016-01-28

9.  Impact of Feature Choice on Machine Learning Classification of Fractional Anomalous Diffusion.

Authors:  Hanna Loch-Olszewska; Janusz Szwabiński
Journal:  Entropy (Basel)       Date:  2020-12-19       Impact factor: 2.524

10.  A Hidden Markov Model for Detecting Confinement in Single-Particle Tracking Trajectories.

Authors:  Paddy J Slator; Nigel J Burroughs
Journal:  Biophys J       Date:  2018-09-13       Impact factor: 4.033

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.