| Literature DB >> 34048020 |
Christine A Boehm1, Jean A Nemzek2.
Abstract
Numerous regulatory bodies around the world require analgesics for rodents undergoing surgery to induce sepsis. Well-controlled pain will decrease morbidity. Options for analgesics include NSAIDs, local analgesics, and opioids. Supportive care can also decrease stress to post-operative animals. As well, humane endpoints should be agreed upon before the study commences so as to alleviate unnecessary pain and distress.Entities:
Keywords: Analgesia; Cecal ligation and puncture; Cecal slurry; Colon ascendens stent peritonitis and fibrin clot implantation; Humane endpoints; Mouse; Sepsis
Year: 2021 PMID： 34048020 DOI： 10.1007/978-1-0716-1488-4_19
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745