Literature DB >> 34024939

The effect of Dean, Reynolds, and Womersley number on the flow in a spherical cavity on a curved round pipe. Part 1. Fluid mechanics in the cavity as a canonical flow representing intracranial aneurysms.

Fanette Chassagne1, Michael C Barbour1, Venkat K Chivukula2, Nathanael Machicoane3, Louis J Kim4,5, Michael R Levitt1,4,5, Alberto Aliseda1,4.   

Abstract

Flow in side-wall cerebral aneurysms can be ideally modelled as the combination of flow over a spherical cavity and flow in a curved circular pipe, two canonical flows. Flow in a curved pipe is known to depend on the Dean number De, combining the effects of Reynolds number, Re, and of the curvature along the pipe centreline, κ. Pulsatility in the flow introduces a dependency on the Womersley number Wo. Using stereo PIV measurements, this study investigated the effect of these three key non-dimensional parameters, by modifying pipe curvature (De), flow-rate (Re), and pulsatility frequency (Wo), on the flow patterns in a spherical cavity. A single counter-rotating vortex was observed in the cavity for all values of pipe curvature κ and Re, for both steady and pulsatile inflow conditions. Increasing the pipe curvature impacted both the flow patterns in the pipe and the cavity, by shifting the velocity profile towards the cavity opening and increasing the flow rate into the cavity. The circulation in the cavity was found to collapse well with only the Dean number, for both steady and pulsatile inflows. For pulsatile inflow, the counter-rotating vortex was unstable and the location of its centre over time was impacted by the curvature of the pipe, as well as the Re and the Wo in the freestream. The circulation in the cavity was higher for steady inflow than for the equivalent average Reynolds and Dean number pulsatile inflow, with very limited impact of the Womersley in the range studied.

Entities:  

Keywords:  Cavity Flow; Cerebral Aneurysm; Dean Number; Flow in Curved Vessels; Hemodynamics; Reynolds Number; Womersely Number

Year:  2021        PMID: 34024939      PMCID: PMC8136084          DOI: 10.1017/jfm.2020.1114

Source DB:  PubMed          Journal:  J Fluid Mech        ISSN: 0022-1120            Impact factor:   3.627


  19 in total

1.  Method for the calculation of velocity, rate of flow and viscous drag in arteries when the pressure gradient is known.

Authors:  J R WOMERSLEY
Journal:  J Physiol       Date:  1955-03-28       Impact factor: 5.182

2.  Pulsatile flow effects on the hemodynamics of intracranial aneurysms.

Authors:  Trung B Le; Iman Borazjani; Fotis Sotiropoulos
Journal:  J Biomech Eng       Date:  2010-11       Impact factor: 2.097

3.  An analysis of the geometry of saccular intracranial aneurysms.

Authors:  L Parlea; R Fahrig; D W Holdsworth; S P Lownie
Journal:  AJNR Am J Neuroradiol       Date:  1999 Jun-Jul       Impact factor: 3.825

Review 4.  Aneurysm Formation, Growth, and Rupture: The Biology and Physics of Cerebral Aneurysms.

Authors:  Pavlos Texakalidis; Ahmad Sweid; Nikolaos Mouchtouris; Eric C Peterson; Chrissa Sioka; Leonardo Rangel-Castilla; John Reavey-Cantwell; Pascal Jabbour
Journal:  World Neurosurg       Date:  2019-07-16       Impact factor: 2.104

5.  Large Neck and Strong Ostium Inflow as the Potential Causes for Delayed Occlusion of Unruptured Sidewall Intracranial Aneurysms Treated by Flow Diverter.

Authors:  T Su; P Reymond; O Brina; P Bouillot; P Machi; B M A Delattre; L Jin; K O Lövblad; M I Vargas
Journal:  AJNR Am J Neuroradiol       Date:  2020-02-13       Impact factor: 3.825

6.  Hemodynamics of Cerebral Aneurysms.

Authors:  Daniel M Sforza; Christopher M Putman; Juan Raul Cebral
Journal:  Annu Rev Fluid Mech       Date:  2009-01-01       Impact factor: 18.511

Review 7.  High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis.

Authors:  H Meng; V M Tutino; J Xiang; A Siddiqui
Journal:  AJNR Am J Neuroradiol       Date:  2013-04-18       Impact factor: 3.825

8.  Effects of Reynolds and Womersley Numbers on the Hemodynamics of Intracranial Aneurysms.

Authors:  Hafez Asgharzadeh; Iman Borazjani
Journal:  Comput Math Methods Med       Date:  2016-10-26       Impact factor: 2.238

Review 9.  Thrombosis in Cerebral Aneurysms and the Computational Modeling Thereof: A Review.

Authors:  Malebogo N Ngoepe; Alejandro F Frangi; James V Byrne; Yiannis Ventikos
Journal:  Front Physiol       Date:  2018-04-04       Impact factor: 4.566

10.  Sidewall Aneurysm Geometry as a Predictor of Rupture Risk Due to Associated Abnormal Hemodynamics.

Authors:  Hailin Wan; Liang Ge; Lei Huang; Yeqing Jiang; Xiaochang Leng; Xiaoyuan Feng; Jianping Xiang; Xiaolong Zhang
Journal:  Front Neurol       Date:  2019-08-14       Impact factor: 4.003

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  2 in total

1.  The effect of Dean, Reynolds and Womersley numbers on the flow in a spherical cavity on a curved round pipe. Part 2. The haemodynamics of intracranial aneurysms treated with flow-diverting stents.

Authors:  Michael C Barbour; Fanette Chassagne; Venkat K Chivukula; Nathanael Machicoane; Louis J Kim; Michael R Levitt; Alberto Aliseda
Journal:  J Fluid Mech       Date:  2021-03-31       Impact factor: 3.627

2.  On the Potential Self-Amplification of Aneurysms Due to Tissue Degradation and Blood Flow Revealed From FSI Simulations.

Authors:  Haifeng Wang; Daniel Balzani; Vijay Vedula; Klemens Uhlmann; Fathollah Varnik
Journal:  Front Physiol       Date:  2021-12-10       Impact factor: 4.566

  2 in total

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