Cristina Barnadas-Solé1,2, María Fernanda Zerón-Rugerio3,4, Álvaro Hernáez5,6, Javier Foncillas-Corvinos1,2, Trinitat Cambras7, Maria Izquierdo-Pulido8,9. 1. Clínica Sagrada Familia, Barcelona, Spain. 2. Hospital Universitari del Sagrat Cor de Barcelona, Barcelona, Spain. 3. Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain. 4. INSA-UB, Nutrition and Food Safety Research Institute, Barcelona, Spain. 5. August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, Spain. 6. Consorcio CIBER, M.P. Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. 7. Department of Biochemistry and Physiology, School of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain. 8. Department of Nutrition, Food Science and Gastronomy, School of Pharmacy and Food Science, University of Barcelona, Barcelona, Spain. maria_izquierdo@ub.edu. 9. INSA-UB, Nutrition and Food Safety Research Institute, Barcelona, Spain. maria_izquierdo@ub.edu.
Abstract
BACKGROUND: Previous research has shown that sleep can play a role in obesity and weight loss. However, the association of sleep with weight loss in patients with severe obesity after bariatric surgery remains unexplored. We aimed to evaluate the role of sleep in weight loss evolution in a cohort of patients who underwent sleeve gastrectomy. METHODS: A cohort of 252 patients with severe obesity (75.7% women; age [mean ± SD] 47.7 ± 10.8 years; BMI 44.2 ± 5.9 kg/m2) was followed for 1 year after surgery. Anthropometric, biochemical, physical activity, sleep (bedtime, wakeup time, and sleep duration) and dietary intake variables were collected pre- and post-surgery (1 year). Linear and non-linear regression models were used to examine the associations between sleep variables and weight loss. Participants were grouped into 'early' and 'late' sleepers according to a bedtime threshold (before or after 24:00 h), and the differences in weight loss, physical activity, meal timing, and dietary intake between groups were studied. RESULTS: 1-h increments in bedtime were linearly associated with less excess weight loss (EWL) [-2.23%; 95%CI: -3.37; -0.70; p = 0.005] 1 year after the sleeve gastrectomy. Late sleepers lost less weight (-5.64% of EWL [95%CI: -10.11; -1.17]; p = 0.014) when compared to early sleepers and showed a higher energy intake after 21:00 h (8.66% of total energy intake [95% CI: 4.87; 12.46]; p < 0.001). CONCLUSIONS: Late bedtime is associated with less success of weight loss 1 year after the sleeve gastrectomy. Late sleepers consumed more of their calories closer to bedtime. Our results highlight the relevance of considering recommendations on bedtime and meal timing for patients after bariatric surgery.
BACKGROUND: Previous research has shown that sleep can play a role in obesity and weight loss. However, the association of sleep with weight loss in patients with severe obesity after bariatric surgery remains unexplored. We aimed to evaluate the role of sleep in weight loss evolution in a cohort of patients who underwent sleeve gastrectomy. METHODS: A cohort of 252 patients with severe obesity (75.7% women; age [mean ± SD] 47.7 ± 10.8 years; BMI 44.2 ± 5.9 kg/m2) was followed for 1 year after surgery. Anthropometric, biochemical, physical activity, sleep (bedtime, wakeup time, and sleep duration) and dietary intake variables were collected pre- and post-surgery (1 year). Linear and non-linear regression models were used to examine the associations between sleep variables and weight loss. Participants were grouped into 'early' and 'late' sleepers according to a bedtime threshold (before or after 24:00 h), and the differences in weight loss, physical activity, meal timing, and dietary intake between groups were studied. RESULTS: 1-h increments in bedtime were linearly associated with less excess weight loss (EWL) [-2.23%; 95%CI: -3.37; -0.70; p = 0.005] 1 year after the sleeve gastrectomy. Late sleepers lost less weight (-5.64% of EWL [95%CI: -10.11; -1.17]; p = 0.014) when compared to early sleepers and showed a higher energy intake after 21:00 h (8.66% of total energy intake [95% CI: 4.87; 12.46]; p < 0.001). CONCLUSIONS: Late bedtime is associated with less success of weight loss 1 year after the sleeve gastrectomy. Late sleepers consumed more of their calories closer to bedtime. Our results highlight the relevance of considering recommendations on bedtime and meal timing for patients after bariatric surgery.
Authors: Anita P Courcoulas; Susan Z Yanovski; Denise Bonds; Thomas L Eggerman; Mary Horlick; Myrlene A Staten; David E Arterburn Journal: JAMA Surg Date: 2014-12 Impact factor: 14.766
Authors: Jeffrey I Mechanick; Adrienne Youdim; Daniel B Jones; W Timothy Garvey; Daniel L Hurley; M Molly McMahon; Leslie J Heinberg; Robert Kushner; Ted D Adams; Scott Shikora; John B Dixon; Stacy Brethauer Journal: Endocr Pract Date: 2013 Mar-Apr Impact factor: 3.443
Authors: T Ruiz-Lozano; J Vidal; A de Hollanda; F A J L Scheer; M Garaulet; M Izquierdo-Pulido Journal: Clin Nutr Date: 2016-02-16 Impact factor: 7.324
Authors: Athena H Robinson; Sarah Adler; Helen B Stevens; Alison M Darcy; John M Morton; Debra L Safer Journal: Surg Obes Relat Dis Date: 2014-02-07 Impact factor: 4.734