| Literature DB >> 34015209 |
Yoshio Yamamoto1, Mamoru Kawakami1,2, Masakazu Minetama1, Masafumi Nakagawa1, Masatoshi Teraguchi1, Ryohei Kagotani1, Yoshimasa Mera1, Tadashi Sumiya1, Sachika Matsuo1, Tomoko Kitano1, Yukihiro Nakagawa1.
Abstract
STUDYEntities:
Keywords: Anxiety; Catastrophization; Depression; Fear; Spinal stenosis
Year: 2021 PMID: 34015209 PMCID: PMC9066246 DOI: 10.31616/asj.2020.0402
Source DB: PubMed Journal: Asian Spine J ISSN: 1976-1902
Comparison of clinical characteristics between satisfied and dissatisfied groups at the baseline
| Characteristic | Satisfied group (n=128) | Dissatisfied group (n=29) | |
|---|---|---|---|
| Age (yr) | 69.7±8.1 | 70.2±10.2 | 0.79 |
| Sex | 0.53 | ||
| Female | 58 | 15 | |
| Male | 70 | 14 | |
| Body mass index (kg/m2) | 24.1±23.1 | 23.9±2.6 | 0.79 |
| Comorbidities (%) | |||
| Hypertension | 87 (68.0) | 21 (72.4) | 0.64 |
| Diabetes | 25 (19.5) | 9 (31.0) | 0.17 |
| Heart disease | 14 (10.9) | 3 (10.3) | 0.93 |
| Pulmonary disease | 6 (4.7) | 0 (0) | 0.23 |
| Smoker | 13 (10.2) | 5 (17.2) | 0.28 |
| Duration of symptoms (mo) | 7.7±8.0 | 9.8±11.6 | 0.12 |
| Moderate or severe stenotic levels (%) | 0.30 | ||
| 0 | 21 (16.4) | 4 (13.8) | |
| 1 | 50 (39.1) | 10 (34.5) | |
| 2 | 40 (31.3) | 7 (24.1) | |
| ≥3 | 17 (13.3) | 8 (27.6) | |
| No. of decompressions | 3.1±1.8 | 3.1±1.1 | 0.96 |
| Fusion surgery (%) | 80 (62.5) | 16 (55.2) | 0.47 |
| Invasiveness index | 9.5±6.1 | 9.2±5.8 | 0.93 |
| ZCQ | |||
| Symptom severity | 3.5±0.6 | 3.6±0.6 | 0.74 |
| Physical function | 2.6±0.6 | 2.8±0.5 | 0.17 |
| VAS | |||
| Back pain | 61.1±28.5 | 55.8±22.7 | 0.27 |
| Leg pain | 68.9±25.3 | 67.0±18.4 | 0.33 |
| Leg numbness | 62.3±28.8 | 66.2±25.0 | 0.66 |
| JOABPEQ | |||
| Pain-related disorders | 42.0±32.4 | 47.9±35.8 | 0.39 |
| Lumbar dysfunction | 57.4±28.7 | 55.1±23.9 | 0.50 |
| Gait disturbance | 31.6±24.0 | 28.7±22.3 | 0.61 |
| Social life dysfunction | 35.5±20.9 | 37.9±18.7 | 0.37 |
| Psychological disorders | 45.2±16.4 | 40.1±20.0 | 0.10 |
| SF-36 | |||
| Physical functioning | 44.8±22.9 | 44.1±21.1 | 0.84 |
| Bodily pain | 30.9±15.6 | 27.9±12.7 | 0.24 |
| Role physical | 40.6±25.4 | 39.1±26.2 | 0.92 |
| Role emotional | 49.0±30.8 | 37.2±24.0 | 0.08 |
| Mental health | 59.6±21.3 | 47.0±16.2 | 0.01 |
| Social functioning | 61.2±28.1 | 57.1±21.9 | 0.34 |
| Vitality | 49.1±22.0 | 40.6±19.4 | 0.06 |
| General health | 50.0±14.7 | 42.8±16.8 | 0.02 |
| HADS | |||
| Depression | 5.3±3.6 | 7.0±3.7 | 0.03 |
| Anxiety | 5.2±3.5 | 7.6±3.0 | 0.00 |
| PCS total | 31.0±10.9 | 34.3±11.5 | 0.08 |
| Rumination | 15.2±4.1 | 16.3±4.6 | 0.05 |
| Helplessness | 9.9±5.0 | 10.7±5.4 | 0.30 |
| Magnification | 5.9±3.1 | 7.3±2.8 | 0.01 |
| PASS-20 | 42.3±18.1 | 43.9±14.3 | 0.68 |
| Cognitive anxiety | 12.7±6.1 | 13.2±4.8 | 0.71 |
| Escape/avoidance | 11.9±4.7 | 12.3±4.1 | 0.74 |
| Fear | 11.7±6.1 | 12.2±4.8 | 0.70 |
| Physiological anxiety | 5.9±4.2 | 6.2±3.8 | 0.55 |
Values are presented as mean±standard deviation or number (%).
ZCQ, Zurich Claudication Questionnaire; VAS, Visual Analog Scale; JOABPEQ, Japanese Orthopaedic Association Back Pain Evaluation Questionnaire; SF-36, Medical Outcomes Study 36-Item Short-Form General Health Survey; HADS, Hospital Anxiety and Depression Scale; PCS, Pain Catastrophizing Scale; PASS-20, Pain Anxiety Symptoms Scale.
By Student t-test.
By Pearson’s chi-square test.
By Mann-Whitney U-test.
Number of patients with spinal stenosis at each spinal level
| Level | Satisfied group (n=128) | Dissatisfied group (n=29) | |||||||
|---|---|---|---|---|---|---|---|---|---|
|
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| Minor stenosis | Moderate stenosis | Severe stenosis | Extreme stenosis | Minor stenosis | Moderate stenosis | Severe stenosis | Extreme stenosis | ||
| L1–L2 | 115 | 12 | 1 | 0 | 24 | 3 | 2 | 0 | 0.21 |
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| L2–L3 | 100 | 17 | 10 | 1 | 17 | 9 | 3 | 0 | 0.12 |
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| L3–L4 | 61 | 42 | 23 | 2 | 14 | 6 | 6 | 3 | 0.25 |
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| L4–L5 | 52 | 22 | 47 | 7 | 13 | 4 | 10 | 2 | 0.82 |
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| L5–S1 | 120 | 6 | 2 | 0 | 28 | 1 | 0 | 0 | 0.36 |
Data were analyzed using Pearson’s chi-square test.
Comparison of clinical outcomes between satisfied and dissatisfied groups at 6 months postoperatively
| Variable | At 6 months | Mean change at 6 months | Difference between groups | |||
|---|---|---|---|---|---|---|
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| Satisfied group (n=128) | Dissatisfied group (n=29) | Satisfied group (n=128) | Dissatisfied group (n=29) | Satisfied minus dissatisfied group | ||
| ZCQ | ||||||
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| Symptom severity | 2.4±0.7 | 3.5±0.6 | 0.00 | −1.1 (−1.3 to −1.0) | −0.2 (−0.3 to 0) | −1.0 (−1.4 to −0.7) |
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| Physical function | 1.7±0.6 | 2.6±0.6 | 0.00 | −0.9 (−1.0 to −0.8) | −0.1 (−0.3 to 0) | −0.8 (−1.0 to −0.5) |
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| Satisfaction | 1.7±0.4 | 3.2±0.4 | 0.00 | |||
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| VAS | ||||||
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| Back pain | 32.0±28.2 | 52.6±24.4 | 0.00 | −28.8 (−35.1 to −22.4) | −3.3 (−16.4 to 9.9) | −25.5 (−40.3 to −10.7) |
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| Leg pain | 32.1±28.8 | 61.9±24.8 | 0.00 | −36.5 (−43.0 to −30.0) | −5.1 (−15.9 to 5.6) | −34.0 (−48.7 to −19.4) |
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| Leg numbness | 33.7±29.6 | 64.0±23.6 | 0.00 | −28.2 (−34.8 to −21.6) | −2.3 (−14.1 to 9.6) | −28.1 (−42.9 to −13.3) |
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| JOABPEQ-acquired points | ||||||
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| Pain-related disorders | 36.6 (30.5 to 42.7) | 2.4 (−11.5 to 16.2) | 33.9 (19.7 to 18.2) | |||
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| Lumbar dysfunction | 14.2 (8.6 to 19.9) | −16.3 (−29.5 to 3.1) | 30.0 (17.0 to 42.9) | |||
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| Gait disturbance | 41.9 (36.8 to 47.1) | 3.8 (−7.1 to 14.7) | 38.1 (26.1 to 50.1) | |||
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| Social life dysfunction | 26.1 (21.8 to 30.3) | −26.3 (−13.1 to 0.4) | 32.8 (23.3 to 42.2) | |||
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| Psychological disorders | 15.4 (12.5 to 18.3) | −2.9 (−9.7 to 3.8) | 18.7 (11.7 to 25.6) | |||
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| SF-36 | ||||||
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| Physical functioning | 69.0±22.2 | 42.8±20.3 | 0.00 | 24.0 (19.9 to 28.1) | −1.3 (−8.8 to 6.1) | 25.3 (16.1 to 34.6) |
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| Bodily pain | 62.3±21.5 | 33.0±14.6 | 0.00 | 31.3 (27.0 to 35.6) | 5.1 (−2.0 to 12.2) | 26.2 (16.6 to 35.9) |
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| Role physical | 61.2±27.3 | 33.1±24.1 | 0.00 | 20.5 (15.3 to 25.7) | −6.0 (−15.1 to 3.0) | 26.0 (14.0 to 38.0) |
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| Role emotional | 68.0±27.8 | 35.4±28.6 | 0.00 | 18.9 (12.9 to 24.9) | −1.8 (−13.4 to 9.8) | 20.5 (6.9 to 34.1) |
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| Mental health | 73.3±18.0 | 48.9±20.3 | 0.00 | 13.5 (10.0 to 16.9) | 2.0 (−5.4 to 9.3) | 11.5 (3.6 to 19.3) |
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| Social functioning | 77.9±23.8 | 50.9±26.1 | 0.00 | 16.6 (10.9 to 22.3) | −6.3 (−15.6 to 3.1) | 22.5 (14.0 to 38.0) |
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| Vitality | 64.3±18.6 | 37.7±19.6 | 0.00 | 15.3 (11.0 to 19.6) | −2.8 (−10.5 to 4.8) | 18.1 (8.4 to 27.9) |
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| General health | 58.0±16.9 | 44.4±13.5 | 0.00 | 8.0 (5.0 to 11.0) | 1.6 (−4.8 to 8.0) | 6.4 (−0.4 to 13.3) |
Values are presented as mean±standard deviation or odds ratio (95% confidence interval).
ZCQ, Zurich Claudication Questionnaire; VAS, Visual Analog Scale; JOABPEQ, Japanese Orthopaedic Association Back Pain Evaluation Questionnaire; SF-36, Medical Outcomes Study 36-Item Short-Form General Health Survey.
By Student t-test.
By Mann-Whitney U-test.
Logistic regression models of baseline factors that predicted patient dissatisfaction at 6 months postoperatively
| Baseline factor | Odds ratio (95% confidence interval) | |
|---|---|---|
| VAS low back pain ≥median (68.5) | 0.27 (0.10–0.74) | 0.01 |
| SF-36 mental health ≥median (55.0) | 0.26 (0.08–0.89) | 0.03 |
| HADS anxiety ≥median (5.0) | 3.95 (1.16–13.46) | 0.03 |
The independent variables entered into model were age, gender, body mass index, presence of comorbidities, smoking status, duration of symptoms, surgical procedure, predominance of back pain, Zurich Claudication Questionnaire, VAS, Japanese Orthopaedic Association Back Pain Evaluation Questionnaire, SF-36, HADS, Pain Catastrophizing Scale, and Pain Anxiety Symptoms Scale. Nagelkerke’s R=0.26. Hosmer–Lemeshow goodness-of-fit test=0.53.
VAS, Visual Analog Scale; SF-36, Medical Outcomes Study 36-Item Short-Form General Health Survey; HADS, Hospital Anxiety and Depression Scale.