Literature DB >> 34015087

Circulating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients.

Alana F Ogata1,2,3, Chi-An Cheng1,2,3, Michaël Desjardins3,4,5, Yasmeen Senussi1, Amy C Sherman3,4, Megan Powell4, Lewis Novack4, Salena Von4, Xiaofang Li6, Lindsey R Baden3,4,6, David R Walt1,2,3.   

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins were measured in longitudinal plasma samples collected from 13 participants who received two doses of mRNA-1273 vaccine. Eleven of 13 participants showed detectable levels of SARS-CoV-2 protein as early as day 1 after first vaccine injection. Clearance of detectable SARS-CoV-2 protein correlated with production of immunoglobulin G (IgG) and immunoglobulin A (IgA).
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  COVID-19; SARS-CoV-2 antigens; immune responses; mRNA vaccine; spike

Mesh：

Substances：

Year:  2022        PMID： 34015087      PMCID： PMC8241425          DOI： 10.1093/cid/ciab465

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  36 in total

1.  Establishing the Pharmacokinetics of Genetic Vaccines is Essential for Maximising their Safety and Efficacy.

Authors:  Imad Naasani
Journal:  Clin Pharmacokinet       Date:  2022-07-12       Impact factor: 5.577

2.  Activity of mRNA COVID-19 vaccines in patients with lymphoid malignancies.

Authors:  Jennifer L Crombie; Amy C Sherman; Chi-An Cheng; Christine E Ryan; Rebecca Zon; Michaël Desjardins; Peter Baker; Mikaela McDonough; Natalie Izaguirre; Bruce Bausk; Jonathan Krauss; Tal Gilboa; Yasmeen Senussi; David R Walt; Matthew S Davids; Jennifer R Brown; Philippe Armand; Lindsey R Baden; Nicolas Issa
Journal:  Blood Adv       Date:  2021-08-24

3.  The histologic and molecular correlates of COVID-19 vaccine-induced changes in the skin.

Authors:  Cynthia Magro; A Neil Crowson; Linda Franks; Panta Rouhani Schaffer; Patrick Whelan; Gerard Nuovo
Journal:  Clin Dermatol       Date:  2021-07-25       Impact factor: 3.541

4.  Metformin Suppresses Monocyte Immunometabolic Activation by SARS-CoV-2 Spike Protein Subunit 1.

Authors:  Theodore J Cory; Russell S Emmons; Johnathan R Yarbro; Kierstin L Davis; Brandt D Pence
Journal:  Front Immunol       Date:  2021-11-11       Impact factor: 7.561

Review 5.  Rapid testing for coronavirus disease 2019 (COVID-19).

Authors:  Alexander Biby; Xiaochuan Wang; Xinliang Liu; Olivia Roberson; Allya Henry; Xiaohu Xia
Journal:  MRS Commun       Date:  2022-01-20       Impact factor: 2.935

6.  Monitoring Serum Spike Protein with Disposable Photonic Biosensors Following SARS-CoV-2 Vaccination.

Authors:  John S Cognetti; Benjamin L Miller
Journal:  Sensors (Basel)       Date:  2021-08-31       Impact factor: 3.576

7.  Why are we vaccinating children against COVID-19?

Authors:  Ronald N Kostoff; Daniela Calina; Darja Kanduc; Michael B Briggs; Panayiotis Vlachoyiannopoulos; Andrey A Svistunov; Aristidis Tsatsakis
Journal:  Toxicol Rep       Date:  2021-09-14

8.  SARS-CoV-2 Spike triggers barrier dysfunction and vascular leak via integrins and TGF-β signaling.

Authors:  Scott B Biering; Francielle Tramontini Gomes de Sousa; Laurentia V Tjang; Felix Pahmeier; Richard Ruan; Sophie F Blanc; Trishna S Patel; Caroline M Worthington; Dustin R Glasner; Bryan Castillo-Rojas; Venice Servellita; Nicholas T N Lo; Marcus P Wong; Colin M Warnes; Daniel R Sandoval; Thomas Mandel Clausen; Yale A Santos; Victoria Ortega; Hector C Aguilar; Jeffrey D Esko; Charles Y Chui; John E Pak; P Robert Beatty; Eva Harris
Journal:  bioRxiv       Date:  2021-12-13

9.  Penetration of the SARS-CoV-2 Spike Protein across the Blood-Brain Barrier, as Revealed by a Combination of a Human Cell Culture Model System and Optical Biosensing.

Authors:  Dániel Petrovszki; Fruzsina R Walter; Judit P Vigh; Anna Kocsis; Sándor Valkai; Mária A Deli; András Dér
Journal:  Biomedicines       Date:  2022-01-17

Review 10.  How Does Severe Acute Respiratory Syndrome-Coronavirus-2 Affect the Brain and Its Implications for the Vaccines Currently in Use.

Authors:  Philip R Oldfield; Jennifer Hibberd; Byram W Bridle
Journal:  Vaccines (Basel)       Date:  2021-12-21
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